CARDIOVASCULAR DISORDERS IN NEWBORNS WITH INTRAUTERINE GROWTH RETARDATION IN THE EARLY NEONATAL PERIOD

Author(s):  
Margaryta GONCHAR
2003 ◽  
Vol 52 (4) ◽  
pp. 28-32
Author(s):  
D. S. Dodkhoev ◽  
I. I. Evsyukova ◽  
Z. N. Tumasova ◽  
А. V. Harutyunyan

The CK-BB activity in neonates with intrauterine growth retardation (IUGR) was investi-gated and the results were compared to their clinical condition in early neonatal period. The re-sults of the study have shown that the CK-BB activity was increased in neonates with symmetric IUGR and in the presence of chronic placental insufficiency of infectious genesis.


2022 ◽  
pp. 80-84
Author(s):  
E. V. Antsiferova ◽  
T. E. Taranushenko ◽  
N. G. Kiseleva ◽  
E. A. Belyaeva ◽  
T. I. Donskaya

Objective: The analysis of clinical-laboratory peculiarities and the dynamics of glycemia clarifying the terms of blood glucose stabilization during the early neonatal period in children having risk factors of the development of such state.Methods: Open, retrospective , continuous, single-center study was conducted. It was aimed at getting preliminary data that is important for planning further tactics of examining newborns having risk factors on hypoglycemia development (kids having large body weight at birth, children whose mothers have diabetes, newborns having intrauterine growth retardation).The target group of the survey included 522 newborns of both genders in the early neonatal period (from 0 to 7 days of life).Results: There is data on the frequency of first indicated hypoglycemia in newborns having risk factors of the development of such state, clinicallaboratory peculiarities, the dynamics of glycemia during early neonatal period, and also the period of blood glucose stabilization (the age of reaching normoglycemia). Neonatal hypoglycemia was detected in 40.2% of examined children. Laboratory manifestation during the first day of life was noticed 62.9% of cases with the further normalization of glucose level in blood in 24 hours in 73.3% of newborns. Significant reduction of blood glucose was observed in 54.8% of cases requiring hypoglycemia therapy with parenteral prescription of 10% glucose solution. Hypoglycemia jugulated against oral correction of 5% glucoses solution in 40.5 % of cases. 4.8% of children got the level of glucose stabilized after introduction of supplementary feeding.Conclusion: The results of the newborns having risk factors on hypoglycemia development (kids having large body weight at birth, children whose mothers have diabetes, newborns having intrauterine growth retardation) examinations are presented. The peculiarities of neonatal hypoglycemia are: the absence of a typical clinical symptoms among 89% of children. Asymptomatic course of hypoglycemia confirms the importance and necessity of glycemia monitoring in the early neonatal period in order to conduct timely and adequate therapy.


2017 ◽  
Vol 98 (1) ◽  
pp. 44-52 ◽  
Author(s):  
V V Derevtsov

Aim. To evaluate some health aspects of children born with different types of intrauterine growth restriction during the early neonatal period.Methods. Clinical and anamnestic, physical, laboratory, electrophysiological, ultrasound and statistical methods were used. Children’s past medical history, development during early neonatal period, physical development, functioning of autonomic nervous system and cardiovascular system were assessed.Results. It was revealed that development of different types of intrauterine growth restriction is related to father and mother’s age at the time of pregnancy, women’s body mass before pregnancy, and time of pregnancy complication development (abortion risk, pre-eclampsia, arterial hypertension, Rh-immunization, edema). Fetuses with asymmetric type of intrauterine growth retardation had survived hypoxia more often (by 4.87 times). Children with symmetrical type of intrauterine growth retardation were more often born by C-section (by 2.66 times), with smaller anthropometric measurements, with more frequent and severe hypotrophy, moderate and severe cerebral ischemia and mild intracranial hemorrhage, cryptorchidism, kidney diseases, atrial septal defects, muscular ventricular septal defects, open arterial duct, and depleted reserves. Children with asymmetric type of intrauterine growth retardation more often had hypoglycemia, jaundice, polycythemia, restricted adaptation reserves, myocardial metabolic disorders, anterior mitral valve leaflet prolapse, posthypoxic changes similar to hypertrophic cardiopathy.Conclusion. Revealed features of past medical history, development during early neonatal period of life, physical development, functioning of autonomic nervous system and cardiovascular system in different types of children’s intrauterine growth restriction can promote formulation of criteria for early diagnosis of adaptive and reserve disorders and identification of dispensary groups.


2019 ◽  
Vol 36 (4) ◽  
pp. 21-26
Author(s):  
Anton D. Yuditskiy ◽  
Tatyana V. Kovalenko ◽  
Irina N. Petrova

Aim. To study the perinatal features and sickness rate of newborns of different gestation age with intrauterine growth retardation (IUGR). Materials and methods. Group 1 (n = 82) included newborns with gestation age boarders 3236 weeks, group 2 (n = 120) full-term newborns with gestation age 3740 weeks. Characteristic features of anamnesis, gestation period and labor were evaluated; clinical and laboratory-instrumental investigations were performed. Results. Early hypoglycemia during the first hours of life was registered in 46.3% of premature newborns with IUGR and in 26.7 % of full-term newborns (p 0.01), transitory hypocalcaemia in 13.4 and 20.0 %, respectively. In patients of group 1 chronic intrauterine fetal hypoxia (25.7 %) (p 0.05), intranatal asphyxia (40.2 %) (p 0.05), respiratory distress-syndrome at early neonatal period (34.1 %) (p 0.01) were registered more often. During the neonatal period, no differences in frequency and character of perinatal nervous system lesions were detected in the examined groups. Conclusions. Thus, there were obtained the proofs of significant influence of gestation age on the course of perinatal period, character and severity of pathological states in newborns with IUGR.


2016 ◽  
pp. 43-47
Author(s):  
O.V. Basystyi ◽  

The data of domestic and foreign literature on etiology, pathogenesis and intrauterine growth retardation diagnosis are presented in the paper. It highlights pathogenetic role of nitric oxide deficiency in case of obstetric complications and intrauterine growth retardation. Key words: intrauterine growth retardation (IUGR), system L-arginin–NO, obstetric complications.


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