scholarly journals Reviewing Chitin/Chitosan Nanofibers and Associated Nanocomposites and Their Attained Medical Milestones

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2330
Author(s):  
Iyyakkannu Sivanesan ◽  
Judy Gopal ◽  
Manikandan Muthu ◽  
Juhyun Shin ◽  
Jae-Wook Oh

Chitin/chitosan research is an expanding field with wide scope within polymer research. This topic is highly inviting as chitin/chitosan’s are natural biopolymers that can be recovered from food waste and hold high potentials for medical applications. This review gives a brief overview of the chitin/chitosan based nanomaterials, their preparation methods and their biomedical applications. Chitin nanofibers and Chitosan nanofibers have been reviewed, their fabrication methods presented and their biomedical applications summarized. The chitin/chitosan based nanocomposites have also been discussed. Chitin and chitosan nanofibers and their binary and ternary composites are represented by scattered superficial reports. Delving deep into synergistic approaches, bringing up novel chitin/chitosan nanocomposites, could help diligently deliver medical expectations. This review highlights such lacunae and further lapses in chitin related inputs towards medical applications. The grey areas and future outlook for aligning chitin/chitosan nanofiber research are outlined as research directions for the future.

2020 ◽  
Vol 27 (28) ◽  
pp. 4622-4646 ◽  
Author(s):  
Huayu Liu ◽  
Kun Liu ◽  
Xiao Han ◽  
Hongxiang Xie ◽  
Chuanling Si ◽  
...  

Background: Cellulose Nanofibrils (CNFs) are natural nanomaterials with nanometer dimensions. Compared with ordinary cellulose, CNFs own good mechanical properties, large specific surface areas, high Young's modulus, strong hydrophilicity and other distinguishing characteristics, which make them widely used in many fields. This review aims to introduce the preparation of CNFs-based hydrogels and their recent biomedical application advances. Methods: By searching the recent literatures, we have summarized the preparation methods of CNFs, including mechanical methods and chemical mechanical methods, and also introduced the fabrication methods of CNFs-based hydrogels, including CNFs cross-linked with metal ion and with polymers. In addition, we have summarized the biomedical applications of CNFs-based hydrogels, including scaffold materials and wound dressings. Results: CNFs-based hydrogels are new types of materials that are non-toxic and display a certain mechanical strength. In the tissue scaffold application, they can provide a micro-environment for the damaged tissue to repair and regenerate it. In wound dressing applications, it can fit the wound surface and protect the wound from the external environment, thereby effectively promoting the healing of skin tissue. Conclusion: By summarizing the preparation and application of CNFs-based hydrogels, we have analyzed and forecasted their development trends. At present, the research of CNFs-based hydrogels is still in the laboratory stage. It needs further exploration to be applied in practice. The development of medical hydrogels with high mechanical properties and biocompatibility still poses significant challenges.


2020 ◽  
Vol 26 (40) ◽  
pp. 5188-5204
Author(s):  
Uzair Nagra ◽  
Maryam Shabbir ◽  
Muhammad Zaman ◽  
Asif Mahmood ◽  
Kashif Barkat

Nanosized particles, with a size of less than 100 nm, have a wide variety of applications in various fields of nanotechnology and biotechnology, especially in the pharmaceutical industry. Metal nanoparticles [MNPs] have been synthesized by different chemical and physical procedures. Still, the biological approach or green synthesis [phytosynthesis] is considered as a preferred method due to eco-friendliness, nontoxicity, and cost-effective production. Various plants and plant extracts have been used for the green synthesis of MNPs, including biofabrication of noble metals, metal oxides, and bimetallic combinations. Biomolecules and metabolites present in plant extracts cause the reduction of metal ions into nanosized particles by one-step preparation methods. MNPs have remarkable attractiveness in biomedical applications for their use as potential antioxidant, anticancer and antibacterial agents. The present review offers a comprehensive aspect of MNPs production via top-to-bottom and bottom-to-top approach with considerable emphasis on green technology and their possible biomedical applications. The critical parameters governing the MNPs formation by plant-based synthesis are also highlighted in this review.


Filomat ◽  
2016 ◽  
Vol 30 (4) ◽  
pp. 937-943 ◽  
Author(s):  
Buket Simsek ◽  
Ahmet Yardimci

In this paper we survey the 3D reconstruction of an object from its 2D cross-sections has many applications in different fields of sciences such as medical physics and biomedical applications. The aim of this paper is to give not only the Bezier curves in medical applications, but also by using generating functions for the Bernstein basis functions and their identities, some combinatorial sums involving binomial coefficients are deriven. Finally, we give some comments related to the above areas.


Author(s):  
Makoto Anraku ◽  
Shinsuke Ifuku ◽  
Daisuke Iohara ◽  
Fumitoshi Hirayama ◽  
Masaki Otagiri ◽  
...  

2018 ◽  
Vol 400 (1) ◽  
pp. 39-62 ◽  
Author(s):  
Nagendra Kumar Kaushik ◽  
Bhagirath Ghimire ◽  
Ying Li ◽  
Manish Adhikari ◽  
Mayura Veerana ◽  
...  

Abstract Non-thermal atmospheric pressure plasma has been proposed as a new tool for various biological and medical applications. Plasma in close proximity to cell culture media or water creates reactive oxygen and nitrogen species containing solutions known as plasma-activated media (PAM) or plasma-activated water (PAW) – the latter even displays acidification. These plasma-treated solutions remain stable for several days with respect to the storage temperature. Recently, PAM and PAW have been widely studied for many biomedical applications. Here, we reviewed promising reports demonstrating plasma-liquid interaction chemistry and the application of PAM or PAW as an anti-cancer, anti-metastatic, antimicrobial, regenerative medicine for blood coagulation and even as a dental treatment agent. We also discuss the role of PAM on cancer initiation cells (spheroids or cancer stem cells), on the epithelial mesenchymal transition (EMT), and when used for metastasis inhibition considering its anticancer effects. The roles of PAW in controlling plant disease, seed decontamination, seed germination and plant growth are also considered in this review. Finally, we emphasize the future prospects of PAM, PAW or plasma-activated solutions in biomedical applications with a discussion of the mechanisms and the stability and safety issues in relation to humans.


2020 ◽  
Vol 8 (26) ◽  
pp. 5578-5596
Author(s):  
Yuzhen Li ◽  
Yingying Gan ◽  
Chengnan Li ◽  
Yi Yan Yang ◽  
Peiyan Yuan ◽  
...  

An overview of various cell membrane-engineered hybrid soft nanocomposites for medical applications.


Nanoscale ◽  
2014 ◽  
Vol 6 (16) ◽  
pp. 9477-9493 ◽  
Author(s):  
Fuyuan Ding ◽  
Hongbing Deng ◽  
Yumin Du ◽  
Xiaowen Shi ◽  
Qun Wang

This review highlights the recent advancements in the preparation and application of chitin and chitosan originated nanofibrous materials in biomedicine.


2020 ◽  
Vol 8 (36) ◽  
pp. 8219-8231
Author(s):  
Wumaier Yasen ◽  
Ruijiao Dong ◽  
Aliya Aini ◽  
Xinyuan Zhu

Supramolecular block copolymers with a dynamically reversible nature and hierarchical microphase-separated structures can greatly enrich the library of pharmaceutical carriers and outline future research directions for biological applications.


2010 ◽  
Vol 28 (1) ◽  
pp. 142-150 ◽  
Author(s):  
R. Jayakumar ◽  
M. Prabaharan ◽  
S.V. Nair ◽  
H. Tamura

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