A Novel Approach That May Explain the Role of Staphylococcus aureus, Polycations, Neutrophils Pro-Inflammatory Agonists and the Bacteriolysis and Auto Immune Phenomena as Possible Major Events in the Pathogenesis of Atopic Dermatitis: A Working Hypothesis

2019 ◽  
Vol 10 (5) ◽  
Author(s):  
Isaac Ginsburg ◽  
Erez Koren
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Working Hypothesis ◽  
Novel Approach ◽  
Immune Phenomena

The Role of Staphylococcus Aureus Superantigens in Pediatric Atopic Dermatitis

2018 ◽  
Vol 27 (2) ◽  
pp. 107-112
Author(s):  
Amal A. Wafy ◽  
Wageih S. Elnaghy ◽  
Nashwa El-Far ◽  
Sara A. Hamam ◽  
Mohammed El-Gamasy
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis

scholarly journals Exploring the Role of Staphylococcus Aureus Toxins in Atopic Dermatitis

Toxins ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 321 ◽  
Author(s):  
Fabio Seiti Yamada Yoshikawa ◽  
Josenilson Feitosa de Lima ◽  
Maria Notomi Sato ◽  
Yasmin Álefe Leuzzi Ramos ◽  
Valeria Aoki ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Complex Disease ◽  
Skin Barrier ◽  
Inflammatory Skin Disease ◽  
Innate And Adaptive Immunity ◽  
Concise Review ◽  
Intense Pruritus ◽  
Immunological Factors

Atopic dermatitis (AD) is a chronic and inflammatory skin disease with intense pruritus and xerosis. AD pathogenesis is multifactorial, involving genetic, environmental, and immunological factors, including the participation of Staphylococcus aureus. This bacterium colonizes up to 30–100% of AD skin and its virulence factors are responsible for its pathogenicity and antimicrobial survival. This is a concise review of S. aureus superantigen-activated signaling pathways, highlighting their involvement in AD pathogenesis, with an emphasis on skin barrier disruption, innate and adaptive immunity dysfunction, and microbiome alterations. A better understanding of the combined mechanisms of AD pathogenesis may enhance the development of future targeted therapies for this complex disease.

scholarly journals Role of Staphylococcus aureus Nasal Colonization in Atopic Dermatitis in Infants

2009 ◽  
Vol 163 (8) ◽  
Author(s):  
Ankie Lebon ◽  
Joost A. M. Labout ◽  
Henri A. Verbrugh ◽  
Vincent W. V. Jaddoe ◽  
Albert Hofman ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Nasal Colonization

What is the role of Staphylococcus aureus and herpes virus infections in the pathogenesis of atopic dermatitis?

2017 ◽  
Vol 12 (14) ◽  
pp. 1327-1334 ◽  
Author(s):  
Simone Saintive ◽  
Eliane Abad ◽  
Dennis de C Ferreira ◽  
Mayra Stambovsky ◽  
Fernanda S Cavalcante ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Herpes Virus ◽  
Virus Infections ◽  
Herpes Virus Infections ◽  
Herpès Virus

scholarly journals Colonization With Staphylococcus aureus in Atopic Dermatitis Patients: Attempts to Reveal the Unknown

2021 ◽  
Vol 11 ◽  
Author(s):  
Patrycja Ogonowska ◽  
Yolanda Gilaberte ◽  
Wioletta Barańska-Rybak ◽  
Joanna Nakonieczna
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Virulence Factors ◽  
Special Interest ◽  
Genetic Background ◽  
Skin Infection ◽  
Healthy Population ◽  
Drug Resistant ◽  
Lesional Skin

Atopic dermatitis (AD) patients are massively colonized with Staphylococcus aureus (S. aureus) in lesional and non-lesional skin. A skin infection may become systemic if left untreated. Of interest, the incidence of multi-drug resistant S. aureus (MRSA) in AD patients is higher as compared to a healthy population, which makes treatment even more challenging. Information on the specific genetic background of S. aureus accompanying and/or causing AD flares would be of great importance in terms of possible treatment option development. In this review, we summarized the data on the prevalence of S. aureus in general in AD skin, and the prevalence of specific clones that might be associated with flares of eczema. We put our special interest in the presence and role of staphylococcal enterotoxins as important virulence factors in the epidemiology of AD-derived S. aureus. Also, we summarize the present and potentially useful future anti-staphylococcal treatment.

scholarly journals The role of Staphylococcus aureus in atopic dermatitis: microbiological and immunological implications

2019 ◽  
Vol 36 (4) ◽  
pp. 485-491 ◽  
Author(s):  
Hanna Tomczak ◽  
Joanna Wróbel ◽  
Dorota Jenerowicz ◽  
Anna Sadowska-Przytocka ◽  
Magda Wachal ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis

scholarly journals An Important Role of α-Hemolysin in Extracellular Vesicles on the Development of Atopic Dermatitis Induced by Staphylococcus aureus

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e100499 ◽  
Author(s):  
Sung-Wook Hong ◽  
Eun-Byul Choi ◽  
Taek-Ki Min ◽  
Ji-Hyun Kim ◽  
Min-Hye Kim ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Extracellular Vesicles
Sign in / Sign up

Export Citation Format

Share Document