Glembotskaya G.T., Eremin S.Yu. Scientific and practical approach to optimizing costs on development and promotion of drugs

2019 ◽  
Vol 2019 (3) ◽  
pp. 47-53
Author(s):  
Галина Глембоцкая ◽  
Galina Glembockaya ◽  
Станислав Еремин ◽  
Stanislav Eremin

In order to identify promising strategic development possibilities for the pharmaceutical industry in the Russian Federation, a pilot study was conducted, which has analyzed the main trends in the development of innovative medicines. As a result of the content analysis of available sources of scientific literature, the characteristics of options used in the world practice for increasing the innovative activity of individual subjects and the pharmaceutical market as a whole are presented. Possible reserves for the further development of the innovative component of the pharmaceutical market within the framework of the concept of personalized medicine according to the P4 principle (predictive - personalized - preventive - participatory) are identified and structured. The results of use by individual pharmaceutical companies of scientifically and practically justified approaches to optimizing the costs of development and promoting drugs are presented. The advantages and real prospects of a generally accepted method to reduce the cost of development by «expanding the pharmacological effect» (label expansion) of already existing drugs with a known safety profile in the world practice are shown. A scientific generalization and structuring of the goals and results of the post-registration phase of clinical trials to expand the pharmacological action of a number of drugs already existed at the market have been carried out.

2021 ◽  
Vol 2142 (1) ◽  
pp. 012010
Author(s):  
V A Kostesha ◽  
D A Shapovalov ◽  
I K Kolesnikova ◽  
D A Biryukov ◽  
A A Chetverikova

Abstract This article reveals the topic of the implementation of information modeling in the legislation of the Russian Federation. The world experience of creating information models of capital construction and the main features of control and standardization of BIM formation are considered. The analysis of the existing legal framework is carried out in relation to the responsibilities of organizations for the formation and maintenance of information models. The scheme of the life cycle of the model was developed. The article is related to the field of highways property complex management. The main features of the formation of BIM roads, their systematization, storage and regular updating were identified. As a result of the study, a geoportal of highways was developed for the modernization of the land and property complex management of highways. It serves as the basis for geoinformation support for information modeling, cadastral, urban planning, inventory and other works on highways. Conclusions and recommendations for the further development of this area in the territory of the Russian Federation are presented.


2019 ◽  
Vol 97 ◽  
pp. 06025
Author(s):  
Alexandra Yakshina ◽  
Galina Vasilovskaya ◽  
Maria Berseneva ◽  
Elena Danilovich ◽  
Oksana Hoffman

In this article we discuss about the main trends by using BIM-technologies in construction in the Russian Federation, possibilities of applying them in construction quality management and in staff training. Weoutlinethenecessity to improve the system of preparation and implementation of BIM-technologies in the new civil engineers educational process within the strategic development of the construction industry because it’s very important for the further development of construction, architecture and other engineering areas. Here we analyze the possibilities of using BIM-technology in education programs for students of various specialties in the absence of real skills to create drawings on the example of the University of Architecture and Civil Engineering.


2017 ◽  
Vol 8 (1) ◽  
pp. 42-49 ◽  
Author(s):  
Nina Bucalo ◽  
Borut Jereb

Abstract The pharmaceutical industry is one of the most competitive businesses in the world. Supply chain in this industry has been directed towards the production of large batches to avoid lack of supplies, and the achievement of regulatory requirements, at the cost of high level of inventory, higher costs and inventory write-off due to expiration or other reasons. In recent years this industry is facing major changes and challenges such as intense globalization processes, increased competition and innovations in technologies, which has broadened and deepened risks in supply chain. The paper reports the results of the study of the risk in distribution processes of Slovenian pharmaceutical companies, which was conducted among five companies and aims to draw attention to risks that arise in supply chain, to emphasize the importance of their management and to present a model for an effective assessment of risk in companies, developed at the Faculty of Logistics.


2017 ◽  
Vol 64 (3) ◽  
pp. 379-394
Author(s):  
Rimantas Stašys ◽  
Ligita Šimanskienė ◽  
Jurgita Paužuolienė

Abstract As a consequence of globalisation, people’s mobility has been increasing, which brought cultural diversity to a number of countries of the world, therefore intercultural competences became a particularly important research object in organisation management. Scientific literature is rich in publications on the topic, however, the latter problem and its specificity has been insufficiently studied in health care organisations whose performance is especially important for each patient and the cost of errors, possibly caused also by insufficient intercultural competences, may be very great. The conducted research justifies the meaning and significance of intercultural competences in health care organisations and identifies the principal problems in organisations faced when communicating in an intercultural environment. The development of intercultural competences was not sufficiently promoted in health care organisations, leaving that to the staff’s responsibility. Quite a few of health care services providers had a poor knowledge of etiquette and did not know much about the customs and traditions of other countries.


2017 ◽  
pp. 17-19
Author(s):  
A. A. Kuzmenko

Currently, tourism is characterized as relevant and popular phenomenon. Around the world, people travel year-round, and every year according to the WTO the number of tourists increases. It is a recognized fact that integrated tourism development in a particular area leads to its socio-economic development. Currently, Russia has considerable natural-recreational potential, is on the way of development of internal tourism, through specific measures.


2020 ◽  
pp. 57-64
Author(s):  
E. A. Bykova

The definitions the concepts of “innovations” and “innovation process” have been adduced, general assessment of the position of the Russian Federation in the world in terms of investment in scientific and technical research and developments (R & D) has been given, the most investment areas in terms of the volume of expenditures on scientific and technical research and development (R & D) have been highlighted . Key arguments that justify the need for innovative development of the pharmaceutical industry in Russia have been presented. The state and structure of the pharmaceutical market in Russia have been considered, the factors of transition of the pharmaceutical industry to an innovative course of development have been specified. Clear results of the implementation of the strategy for the development of the pharmaceutical industry until 2020 have been emphasized. Examples of implementation of the innovation management mechanism at the level of a separate domestic company Biocad have been given.


2018 ◽  
Vol 1 (12) ◽  
pp. 202-206
Author(s):  
Anna Berezina ◽  
Yuriy Katul'skiy

This article provides an overview of legislation in the field of regulation of emissions on the world stage, presents the data of the car Park of the Russian Federation. The analysis of the further development of the automotive industry.


Author(s):  
A S Fedorenko ◽  
A T Burbello ◽  
M V Pokladova ◽  
M A Ivanova

The article presents possible approaches to assessing the financial costs of medicines. The results of the ABC/VEN and ATC DDD analyzes recommended by the Ministry of Health of the Russian Federation and the World Health Organization (WHO) in assessing the financial costs of medicines in a large multidisciplinary hospital are described. The evaluation of ABC/VEN and ATC/DDD analyzes, their advantages and disadvantages is given. It is shown that the ABC/VEN analysis gives only a general idea of planning financial expenditures and ATC/DDD about real drug consumption in the treatment of one patient. The financial costs of treating one patient vary significantly and depend on many factors: disease nosology, severity, division profile, etc. It was determined which factors should be taken into account both in estimating the cost of medicines and in planning financial expenditures for the next year. (For citation: Fedorenko AS, Burbello AT, Pokladova MV, Ivanova MA. What factors need to be considered when assessing the financial costs of medicines. Herald of North-Western State Medical University named after I.I. Mechnikov. 2018;10(2):64-72. doi: 10.17816/mechnikov201810264-72).


2021 ◽  
Vol 106 ◽  
pp. 01013
Author(s):  
Maryam Orzkhanova ◽  
Sakhadin Hubolov ◽  
Esma Polyakova

The article examines the problems and prospects for the development of the digital economy of the Russian Federation in the context of global transformation. It is obvious that the use of digital technologies in the economic sphere is one of the key indicators of the development of a modern state. The processes of introducing digital technologies are accompanied by technological, economic and legal problems, the solution of which requires government intervention. These circumstances determine the relevance of this study. The purpose of the study is to analyze the problems and assess the prospects for the development of digitalization of the Russian economy, as well as develop recommendations for increasing the efficiency of digitalization of the Russian economy and accelerating the pace of implementation of digital technologies, which will contribute to increasing the competitiveness of the Russian Federation in the world community. The process of digitalization of the economy depends on many factors, the analysis of which will determine the prospects for further development.


Author(s):  
N.A. Sidelnikova ◽  
◽  
N.A. Maslovskaya ◽  

The article reveals the current state of the fat and oil sub-sector of the Russian Federation. In the course of the research, the range of problems faced by manufacturers is established. The article reflects the prospects for further development of the fat and oil sub-sector in order to maintain a competitive position in the world market.


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