INCLUSION OF MAGNETIC NANOPARTICLES ОF MAGNETITE INTO PROTEIN PARTICLES OF CATALASE

2020 ◽  
pp. 83-84
Author(s):  
N. Balabushevich ◽  
K. Vlasova ◽  
D. Volodkin ◽  
Yu. Golovin ◽  
N. Klyachko
Keyword(s):  
Magnetic Field ◽  
Enzyme Activity ◽  
Magnetic Nanoparticles ◽  
Low Frequency ◽  
Alternating Magnetic Field ◽  
Precipitation Method ◽  
Immobilized Catalase ◽  
Protein Particles ◽  
Co Precipitation

In this work, vaterite microparticles with an immobilized catalase (enzyme) and magnetic nanoparticles (MNPs) of magnetite, obtained by the co-precipitation method, were used to study the enzyme activity under low frequency alternating magnetic field.

scholarly journals In Vivo Cancer Cells Elimination Guided by Aptamer-Functionalized Gold-Coated Magnetic Nanoparticles and Controlled with Low Frequency Alternating Magnetic Field

Theranostics ◽  
2017 ◽  
Vol 7 (13) ◽  
pp. 3326-3337 ◽  
Author(s):  
Irina V. Belyanina ◽  
Tatiana N. Zamay ◽  
Galina S. Zamay ◽  
Sergey S. Zamay ◽  
Olga S. Kolovskaya ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Cancer Cells ◽  
Low Frequency ◽  
Alternating Magnetic Field

scholarly journals Non-Heating Alternating Magnetic Field Nanomechanical Stimulation of Biomolecule Structures via Magnetic Nanoparticles as the Basis for Future Low-Toxic Biomedical Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2255
Author(s):  
Yuri I. Golovin ◽  
Dmitry Yu. Golovin ◽  
Ksenia Yu. Vlasova ◽  
Maxim M. Veselov ◽  
Azizbek D. Usvaliev ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Low Frequency ◽  
Alternating Magnetic Field ◽  
Cell Organelles ◽  
Transport Vesicles ◽  
Functionalized Magnetic Nanoparticles ◽  
Enzyme Molecules

The review discusses the theoretical, experimental and toxicological aspects of the prospective biomedical application of functionalized magnetic nanoparticles (MNPs) activated by a low frequency non-heating alternating magnetic field (AMF). In this approach, known as nano-magnetomechanical activation (NMMA), the MNPs are used as mediators that localize and apply force to such target biomolecular structures as enzyme molecules, transport vesicles, cell organelles, etc., without significant heating. It is shown that NMMA can become a biophysical platform for a family of therapy methods including the addressed delivery and controlled release of therapeutic agents from transport nanomodules, as well as selective molecular nanoscale localized drugless nanomechanical impacts. It is characterized by low system biochemical and electromagnetic toxicity. A technique of 3D scanning of the NMMA region with the size of several mm to several cm over object internals has been described.

scholarly journals Synthesis of Magnetic Ferrite Nanoparticles with High Hyperthermia Performance via a Controlled Co-Precipitation Method

Nanomaterials ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 1176 ◽  
Author(s):  
Darwish ◽  
Kim ◽  
Lee ◽  
Ryu ◽  
Lee ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Metal Content ◽  
Cobalt Ferrite ◽  
Ferrite Nanoparticles ◽  
Precipitation Method ◽  
Maximum Temperature ◽  
Cancer Treatments ◽  
Prepared Nanoparticles ◽  
Co Precipitation

Magnetic nanoparticles (MNPs) that exhibit high specific loss power (SLP) at lower metal content are highly desirable for hyperthermia applications. The conventional co-precipitation process has been widely employed for the synthesis of magnetic nanoparticles. However, their hyperthermia performance is often insufficient, which is considered as the main challenge to the development of practicable cancer treatments. In particular, ferrite MNPs have unique properties, such as a strong magnetocrystalline anisotropy, high coercivity, and moderate saturation magnetization, however their hyperthermia performance needs to be further improved. In this study, cobalt ferrite (CoFe2O4) and zinc cobalt ferrite nanoparticles (ZnCoFe2O4) were prepared to achieve high SLP values by modifying the conventional co-precipitation method. Our modified method, which allows for precursor material compositions (molar ratio of Fe+3:Fe+2:Co+2/Zn+2 of 3:2:1), is a simple, environmentally friendly, and low temperature process carried out in air at a maximum temperature of 60 °C, without the need for oxidizing or coating agents. The particles produced were characterized using multiple techniques, such as X-ray diffraction (XRD), dynamic light scattering (DLS), transmission electron microscopy (TEM), ultraviolet-visible spectroscopy (UV–Vis spectroscopy), and a vibrating sample magnetometer (VSM). SLP values of the prepared nanoparticles were carefully evaluated as a function of time, magnetic field strength (30, 40, and 50 kA m−1), and the viscosity of the medium (water and glycerol), and compared to commercial magnetic nanoparticle materials under the same conditions. The cytotoxicity of the prepared nanoparticles by in vitro culture with NIH-3T3 fibroblasts exhibited good cytocompatibility up to 0.5 mg/mL. The safety limit of magnetic field parameters for SLP was tested. It did not exceed the 5 × 109 Am−1 s−1 threshold. A saturation temperature of 45 °C could be achieved. These nanoparticles, with minimal metal content, can ideally be used for in vivo hyperthermia applications, such as cancer treatments.

scholarly journals Structure, Luminescence, and Magnetic Properties of Crystalline Manganese Tungstate Doped with Rare Earth Ion

Materials ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3717
Author(s):  
Jae-Young Jung ◽  
Soung-Soo Yi ◽  
Dong-Hyun Hwang ◽  
Chang-Sik Son
Keyword(s):  
Magnetic Field ◽  
Rare Earth ◽  
Sintering Temperature ◽  
Luminescent Properties ◽  
Concentration Quenching ◽  
Rare Earth Ions ◽  
Precipitation Method ◽  
Rare Earth Ion ◽  
Co Precipitation ◽  
Quenching Phenomenon

The precursor prepared by co-precipitation method was sintered at various temperatures to synthesize crystalline manganese tungstate (MnWO4). Sintered MnWO4 showed the best crystallinity at a sintering temperature of 800 °C. Rare earth ion (Dysprosium; Dy3+) was added when preparing the precursor to enhance the magnetic and luminescent properties of crystalline MnWO4 based on these sintering temperature conditions. As the amount of rare earth ions was changed, the magnetic and luminescent characteristics were enhanced; however, after 0.1 mol.%, the luminescent characteristics decreased due to the concentration quenching phenomenon. In addition, a composite was prepared by mixing MnWO4 powder, with enhanced magnetism and luminescence properties due to the addition of dysprosium, with epoxy. To one of the two prepared composites a magnetic field was applied to induce alignment of the MnWO4 particles. Aligned particles showed stronger luminescence than the composite sample prepared with unsorted particles. As a result of this, it was suggested that it can be used as phosphor and a photosensitizer by utilizing the magnetic and luminescent properties of the synthesized MnWO4 powder with the addition of rare earth ions.

Phase-change material filled hollow magnetic nanoparticles for cancer therapy and dual modal bioimaging

Nanoscale ◽  
2015 ◽  
Vol 7 (19) ◽  
pp. 9004-9012 ◽  
Author(s):  
Jinghua Li ◽  
Yan Hu ◽  
Yanhua Hou ◽  
Xinkun Shen ◽  
Gaoqiang Xu ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Cancer Therapy ◽  
Phase Change ◽  
Phase Change Material ◽  
Alternating Magnetic Field ◽  
Change Material

An alternating magnetic field triggered nanocarrier for drug delivery is fabricated for dual modal imaging-guided thermo-chemo cancer therapy.

Convenient synthesis of anisotropic Fe3O4 nanorods by reverse co-precipitation method with magnetic field-assisted

2011 ◽  
Vol 65 (12) ◽  
pp. 1973-1975 ◽  
Author(s):  
Wei Zhang ◽  
Shaoyi Jia ◽  
Qian Wu ◽  
Jingyu Ran ◽  
Songhai Wu ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Precipitation Method ◽  
Convenient Synthesis ◽  
Co Precipitation
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