Effect of General Anesthesia on Intra-ocular Pressure during Ophthalmic Procedures in Our Population

2021 ◽  
Vol 15 (10) ◽  
pp. 2614-2615
Author(s):  
Tariq Pervaiz Khan ◽  
Fakhar Humayun ◽  
Qumber Abbas ◽  
Abaid Ur Rehman ◽  
Faiza Hameed ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
General Anesthesia ◽  
Posterior Segment ◽  
Ocular Motility ◽  
Inhalation Anesthetics ◽  
Intra Ocular Pressure ◽  
Anesthetic Agents ◽  
Department Of Ophthalmology ◽  
Ocular Pressure ◽  
The Mean

Aim: To determine changes in intraocular pressures (IOP) associated with drugs used for general anesthesia (GA) induction in eye surgery. Study design: Observational prospective study Place and duration of study: Department of Ophthalmology, CMH Rawalpindi from 1st March 2015 to 31st May 2016. Methodology: Eighty subjects that were advised to undergone various ophthalmic surgical procedures under GA were included in the study. Visual acuity, intraocular pressure (IOP), extra ocular motility, anterior and dilated posterior segment examination were carried out to determine the ophthalmic status. Mixed anesthetics were used in all patients. IOP was recorded at T1 (10 min before induction of anesthesia), T2 (10 min after intubation), and T3 (at the conclusion of surgery before extudation) using Perkins tonometers. Changes in IOP before induction of GA, after intubation, and just before extubation were recorded. Results: Mean pre-anesthesia IOP for patients of age was 42.3 years with a range of 9-70 years and mean IOP was 16.4 with a range of 10-23 mmHg. There was a significant decrease in the mean IOP at T2 (Perkins: 4-6 mmHg) and T3 (Perkins: 5-8mmHg) as compared to the IOP at T1 (10-18mmHg. The decreases in IOPs at T2 and T3 were similar in both anesthetic groups (T2: P=4-6mmHg; T3: P = 5-8 mmHg). Conclusion: Significant decrease in IOP after GA was observed with mixed anesthetic agents. For management decisions this aspect of general anaesthesia drugs on IOP as noted with currently used anesthetic agents has to be accounted for and decisions are taken accordingly. Keywords: General anesthesia, inhalation anesthetics, intraocular pressure, Perkins tonometers

scholarly journals Non-contact Tonometry Versus Pachymetry Corrected Intraocular Pressure: Any Difference? A Case for Pachymetry during Glaucoma Screening

2019 ◽  
pp. 1-7
Author(s):  
E. Awoyesuku ◽  
A. A. Onua
Keyword(s):  
Intraocular Pressure ◽  
Pressure Measurement ◽  
Corneal Thickness ◽  
Intra Ocular Pressure ◽  
Glaucoma Screening ◽  
Port Harcourt ◽  
Department Of Ophthalmology ◽  
Significant Difference ◽  
Ocular Pressure ◽  
The Mean

Objective: This study sets out to determine if there is any statistical difference in the results of measuring intraocular pressure (IOP) uncorrected for Central Corneal Thickness with Air Puff Tonometry and corrected with pachymetry for clients undergoing screening for glaucoma at the department of Ophthalmology, University of Port Harcourt Teaching Hospital (UPTH), Nigeria. Methods: One hundred and thirty-two (132) adults were screened for glaucoma during the 2019 World Glaucoma week in UPTH Port Harcourt, they had their IOPs measured with Air Puff (Non-contact) Tonometer (Pulsair intelliPuff Tonometer, Keeler), after which they underwent pachymetry (Sonomed Escalon PacScan Plus) to determine corneal thickness after which the corrected IOP was determined by using a correction factor for adjusting IOP based on corneal thickness [1].  The results were analyzed using SPSS version 20 to determine statistical differences. Results: There was a statistically significant difference between intraocular pressure (IOP) measurements when corrected with pachymetry than when it is uncorrected. In our study the mean uncorrected IOP RE and LE was 14.53 mmHg and14.75 mmHg respectively while Corrected IOP RE and LE was 16.37 mmHg and 16.72 mmHg respectively. Conclusion: Intra ocular pressure measurement adjusted with pachymetry for corneal thickness may be a better option for tonometry and we propose this be considered during intra ocular pressure measurement.

scholarly journals INTRA OCULAR PRESSURE

2018 ◽  
Vol 25 (12) ◽  
pp. 1833-1839
Author(s):  
Arsalan Ahmed Rajput ◽  
Azfar Ahmed Mirza ◽  
Ghazi Khan Maree ◽  
Adil Ali Shaikh
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
P Value ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
Intra Ocular Pressure ◽  
Department Of Ophthalmology ◽  
Ocular Pressure ◽  
The Mean

Introduction: The ideal optical properties of the eye requires support of state of the eye-ball which is normally regulated by the intraocular pressure (IOP). There is variation in the measurements of IOP with Goldmann applanation tonometry if the thickness of the central cornea is not uniform, the IOP is high when cornea is thicker and vice versa. Therefore, the central corneal thickness (CCT) is thought to affect the IOP readings, however, as shown, the evidence available remains controversial. The aim of the study was to determine correlation between CCT and IOP. Objectives: To determine the correlation between the Central Corneal Thickness (CCT) and Intra Ocular Pressure (IOP). Study Design: A cross-sectional study. Placeand Duration: Department of Ophthalmology, Aga Khan University Hospital, Karachi from July to December, 2014. Methodology: During the study period of six months total 431 participants were purposively sampled according to the set criteria. Variables included were age, gender, CCT, and IOP. Correlation between IOP and CCT was assessed by using Pearson correlation test, P value of < 0.05 was considered significant. Results: Out of 431 participants, 239 (55.5%) males and 192 (44.5%) females. The mean age was 34.9 ranging from 20 to 50 years. The mean central corneal thickness of right eye was 529 μm with SD ± 39.5 and range of 473-591 μm. The mean intraocular pressure of right eye was 14.7 μm, SD ± 3.1 with a range of 9-21 mmHg. The left eye mean central corneal thickness was 533, SD ± 29.6 with range of 481-589 μm. The mean intraocular pressure of left eye was 15.6, SD ± 3.1 with a range of 10-21 mmHg. Strong positive correlation was found (P-value < 0.001) between central corneal thickness andintra ocular pressure for both eyes. Conclusion: There is positive correlation between CCT and IOP. Therefore, along with the routine ophthalmic examination for intraocular pressure measurements pachymetry should also be considered for accurate interpretation of the results.

Early Post-Operative Effect of Phacoemulsification on Anterior Chamber Depth and Intraocular Pressure in Patients with Cataract

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Mashal Tayyab ◽  
Awaid Abid
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Pressure Change ◽  
P Value ◽  
Iol Implantation ◽  
Intra Ocular Pressure ◽  
Significant Difference ◽  
Ocular Pressure ◽  
The Mean

Purpose:  To determine the Anterior Chamber depth and Intraocular pressure change following uncomplicated phacoemulsification. Study Design:  Quasi experimental study. Place and Duration of Study:  Layyton Rehmatullah Benevolent Trust Free Eye and Cancer Hospital, Lahore from 16/12/2017 to 15/06/2018. Methods:  One hundred and thirty nine patients who came to Layyton Rehmatullah Benevolent Trust Free Eye for phacoemulsification and IOL implantation were included in the study. Anterior Chamber depth was measured with IOL Master and intraocular pressure was determined using Goldmann Applanation Tonometer one day before and one month after surgery. Data was recorded on a self-designed proforma. Comparison between pre- and post-operative data with respect to change was analyzed by chi-square test. P-value ≤ 0.05 was considered significant. Results:  The mean intra-ocular pressure dropped from 14.36 ± 4.19 mmHg to 12.14 ± 4.26 mmHg 1 month after surgery with a mean drop of 2.21 ± 0.65 mmHg while the mean anterior chamber depth increased from 2.31 ± 0.08 mm to 3.59 ± 0.37 mm with a mean increase of 1.29 ± 0.36 mm. There was no statistically significant difference in the mean change of intra-ocular pressure and anterior chamber depth across various subgroups based on patient’s age, gender and duration of cataract. Conclusion:  Phacoemulsification and IOL implantation not only improves the visual acuity by removing the cataract but also deepens the anterior chamber and decreases intra-ocular pressure, which can have a beneficial effect in glaucoma patients. Key Words:  Phacoemulsification, Cataract, Intraocular pressure, Lens, Anterior chamber depth.

scholarly journals Mean Change in Intra-Ocular Pressure in patients undergoing Trabeculectomy with Mitomycin C

2021 ◽  
Vol 15 (5) ◽  
pp. 1044-1046
Author(s):  
Munib Ur Rehman ◽  
Shahid Mahmood Dayal ◽  
Ali Zain Ul Abidin
Keyword(s):  
Intraocular Pressure ◽  
Mitomycin C ◽  
Congenital Glaucoma ◽  
P Value ◽  
Cross Sectional ◽  
Primary Congenital Glaucoma ◽  
Intra Ocular Pressure ◽  
Department Of Ophthalmology ◽  
Significant Difference ◽  
Ocular Pressure

Aim: To examine the outcomes of trabeculectomy followed by mitomycin C in term of mean change in intra-ocular pressure in patients presented with primary congenital glaucoma. Study design: Cross-sectional/observational Place and duration of study: Department of Ophthalmology, Khawaja Muhammad Safdar Medical College, Allama Iqbal Memorial Teaching Hospital, Sialkot from 7th July 2020 to 6thJanuary 2021. Methods: Fortypatients of both genders with ages up to 5 years presented with primary congenital glaucoma were enrolled in this study. Patients demographics were recorded after taking written consent from parents/guardians. All the patients were receivedtrabeculectomy with 0.4mg/ml Mitomycin C was applied below the flap for 2 to 3 minutes. Intraocular pressure was examined preoperatively and at 12th day after surgery. Results:Twenty-four (60%) were males while 16 (40%) were females. 30 (75%) patients were ages <2yearsand 10 (25%) patients had ages >2 years. A significant difference was observed regarding mean change in intra-ocular pressure (pre-operatively 30.48±3.62 versus post-operatively 16.35±2.86) with p-value <0.001. Conclusion: Trabeculectomy with Mitomycin C is very effective for reducing intraocular pressure. A significant decrease in intra-ocular pressure was observed post-operatively. Keywords: Primary congenital glaucoma, Intra-ocular pressure, Trabeculectomy, Mitomycin C

scholarly journals An observational comparative study of intraocular pressure changes in post-operative cataract patients treated with dexamethasone and difluprednate

2020 ◽  
Vol 9 (7) ◽  
pp. 1079
Author(s):  
Sadhana K. Hingorani ◽  
Anupama S. Desai ◽  
Manisha B. Shastri
Keyword(s):  
Intraocular Pressure ◽  
Adverse Effects ◽  
Topical Steroids ◽  
Intra Ocular Pressure ◽  
Ocular Pressure ◽  
The Mean ◽  
Group 2 ◽  
Pressure Changes ◽  
Cataract Patients ◽  
Group 1

Background: Cataract is the leading cause of blindness worldwide. Treatment of cataract is surgical. Topical corticosteroids are routinely used in the treatment of post-operative inflammation following cataract surgery. This study aims to compare the intraocular pressure changes caused by topical steroids (dexamethasone and difluprednate) and to detect adverse effects.Methods: All patients operated by phacoemulsification in ophthalmology Department of SMIMER Surat were taken as subjects. Depending on topical steroids prescribed after surgery, subjects were separated into 2 groups, group 1 - difluprednate and group 2 - dexamethasone. Changes in intra-ocular pressure (IOP) of patients were collected from the data available pre-operative, 1st ,2nd ,3rd ,4th week after surgery and were analyzed. Other parameters whose data were collected are-adverse effects and compliance of patients.Results: In group 1 preoperative mean IOP was 15.5. At the end of 1st week, the mean IOP was significantly increased to 15.8. There was equal rise in IOP during 3rd week and 4th week which means that after 3rd week IOP remains stable. In group 2 preoperative mean IOP was 15.4. At the end of 1st, 2nd, 3rd and 4th there was significant increase in IOP as compared to preoperative mean IOP. Adverse effects were reported more in group 2.Conclusions: In group 1 there was a rise in IOP up to three weeks but after 3rd week IOP remained stable. In group 2 rise in IOP was seen throughout 4 weeks of treatment. Adverse effects seen more in group 2. Compliance of patients was better in group 1.

scholarly journals Intraocular Pressure Reduction after Femtolaser Assisted Cataract Surgery and Its Association with the Use of Ultrasound

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 437
Author(s):  
Hana Abouzeid ◽  
Walter Ferrini ◽  
Murielle Bochud
Keyword(s):  
Intraocular Pressure ◽  
Linear Regression ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Multiple Linear Regression Model ◽  
Study Data ◽  
Department Of Ophthalmology ◽  
Duration Of Surgery ◽  
Ocular Pressure

Background and Objectives: To quantify the change in intraocular pressure (IOP) after phacoemulsification in patients having undergone femtolaser assisted cataract surgery (FLACS), and study the influence of the use of ultrasound on this change. Setting: Jules-Gonin Eye Hospital, University Department of Ophthalmology, Lausanne, Switzerland. Materials and Methods: Interventional study. Methods: All consecutive cases operated with FLACS and with complete data for the studied parameters were selected for inclusion in the study. Data had been prospectively collected and was analysed retrospectively. Linear regression was performed to explore the association of change in IOP with time of measure, ultrasound use, sex, age, and duration of surgery. Results: There was a mean decrease in intraocular pressure of 2.5 mmHg (CI 95% −3.6; −1.4, p < 0.001) postoperatively. No association between the change in intraocular pressure and ultrasound time or effective phaco time was observed when the data were analyzed one at a time or in a multiple linear regression model. There was no association with sex, age, nuclear density, presence of pseudoexfoliation, duration of surgery, and time of ocular pressure measurement. Eyes with preoperative IOP ≥ 21 mmHg had a more significant IOP reduction after surgery (p < 0.0001) as did eyes with an anterior chamber depth <2.5 mm (p = 0.01). Conclusion: There was a decrease in intraocular pressure six months after FLACS in our study similar to that in the published literature for standard phacoemulsification. The use of ultrasound may not influence the size of the decrease, whereas the preoperative IOP and anterior chamber depth do. FLACS may be as valuable as standard phacoemulsification for cases where IOP reduction is needed postoperatively.

scholarly journals Glaucoma characteristics evaluation in myopia – A clinical study

2021 ◽  
Vol 7 (2) ◽  
pp. 195-199
Author(s):  
Helen Rosita J ◽  
Gnanaselvan J ◽  
Amudhavadivu S ◽  
Anna Kurian Mullasseril
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
High Myopia ◽  
Intra Ocular Pressure ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
Ocular Pressure ◽  
The Mean ◽  
One Year ◽  
High Degree

Glaucoma is the leading cause of irreversible blindness, one of the risk factor recognised being high myopia. Intra ocular pressure may be normal in myopic patients, with optic nerve head glaucoma characteristics. Eye ball elongation and optic nerve head tilting may be present in patients with high myopia that will represent field defects mimicking glaucoma. Treating patients with myopia having suspected aspects of glaucoma may be a challenge but even more challenging is the diagnosis of glaucoma in myopic patients.: To evaluate the association of glaucoma features with myopia. To create the awareness regarding the long term follow up.: Patients in the age group of 15 to 45 years who had attended our institution over a period of one year who fulfilled the inclusion and exclusion criteria were subjected for this study. Fifty four patients who were diagnosed to have moderate or high degree myopia were selected for this analytical study. They were subjected to vision, ocular examination, tonometry and results obtained were analysed.: In our study moderate myopes constituted 55.5% and high myopes were 44.5%. The mean Intra ocular pressure and the mean corrected Intra ocular pressure in high myopes were observed to be higher than in moderate myopia. It was observed that higher prevalence of glaucoma was observed in high myopes.: There is a clinically as well as statistically significant difference between mean Intra ocular pressure and mean corrected Intra ocular pressure. So mean corrected Intra ocular pressure should be measured .From our study, there is a clear indication that there is increased prevalence of glaucoma in high myopes.

scholarly journals Referral parameters for diagnosis of glaucoma in general eye clinic at Tilganga Institute of Ophthalmology

2019 ◽  
Vol 11 (1) ◽  
pp. 33-39
Author(s):  
Pratibha Lama Joshi ◽  
Bhaskar Jha ◽  
Indira Paudyal ◽  
Suman Shamsher Thapa
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Normal Group ◽  
Intra Ocular Pressure ◽  
Glaucoma Diagnosis ◽  
Ocular Pressure ◽  
The Mean ◽  
Eye Clinic

Objective: To find out the most common referral parameter among the glaucoma suspects patients from general eye clinic and to establish glaucoma diagnosis. Methods: This study is a retrospective cohort hospital based study. Two hundred patients from January to February 2017 sent to glaucoma clinic as glaucoma suspects were re-evaluated meticulously by glaucoma specialist and were diagnosed as glaucoma, non glaucoma, suspects and ocular hypertension. Results: Out of the 200 patients referred to glaucoma clinic as glaucoma suspects only19% were diagnosed to have glaucoma. The mean age at which glaucoma diagnosed was 55.29(14.4) compared to 41.6(15.1) in normal group. One hundred and sixty five patients were referred on the basis of suspicious optic nerve head, among them 14.5% (24/165) had glaucoma. This study showed that, open angle glaucoma (OAG) 28.9% was the most common type of total glaucoma diagnosed. The mean vertical cup discratio in the OAG group was 0.69±0.1 (0.4 -0.9) compared to 0.56 ± 0.11((0.2-0.8)(p=0.00) normal. The mean intra ocular pressure (IOP) in OAG group was 19.73 ±4.95(11-32) mmHg compared to 16.74± 3.36(10-30) mmHg (p=0.00) in normal group. The mean central corneal thickness (CCT) in OAG group was 533.05 ± 31.24μm (467-606) compared to normal was 534.9±33.6 μm (432-696) (p=0.670). Conclusions: Suspicious optic nerve head is the most common referral parameter between the general ophthalmologist and residents, but this study shows only few of them were diagnosed with glaucoma. This gives us a clue that the ophthalmologists and residents are to be trained better to help them identify the signs of glaucoma on the optic nerve head beside its size, which will reduce unnecessary burden to the resources of patients and hospital.

scholarly journals Efficacy of latanoprost in management of chronic angle closure glaucoma

1970 ◽  
Vol 1 (1) ◽  
pp. 32-36 ◽  
Author(s):  
S Kumar ◽  
A Malik ◽  
M Singh ◽  
S Sood
Keyword(s):  
Intraocular Pressure ◽  
Posterior Segment ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Slit Lamp ◽  
Treatment Results ◽  
Once Daily ◽  
Significant Difference ◽  
The Mean ◽  
Baseline Examination

Background: Chronic angle closure glaucoma is often managed surgically. Aim: To study the effect of Latanoprost 0.005% on intraocular pressure in subjects diagnosed as having chronic angle closure glaucoma. Materials and methods: Forty patients participated in the study. Baseline examination included visual acuity, refraction, slit-lamp examination, intraocular pressure, anterior and posterior segment examination, gonioscopy and perimetry. Patients were treated with Latanoprost 0.005% once daily at bedtime. IOP was recorded at baseline, 2weeks, 4 weeks, 8 weeks and 12 weeks after starting the treatment. Results: The mean age of the study sample was 56.45 years (40-70 years). There were 18 males and 22 females in the study. Mean IOP at baseline was 24.55±3.63. Mean IOP decreased to 17.27±3.19 at 2 weeks, 15.27±3.07 at 4 weeks, 14.60±3.06 at 8 weeks and 14.47±2.66 at 12 weeks. There was a statistically significant reduction in mean IOP (41.03%) at 12 weeks as compared to those of the baseline IOP (p=0.000). There was no significant difference in IOP reduction in eyes with different degrees of angle closure by peripheral anterior synechiae. Conclusion: Latanoprost, a prostaglandin analogue, is effective in reducing IOP in chronic angle closure glaucoma patients and its efficacy is not affected by the degree of angle closure by peripheral anterior synechiae. Key words: latanoprost; chronic angle closure glaucoma; intraocular pressure; peripheral anterior synechiae DOI: 10.3126/nepjoph.v1i1.3671 Nep J Oph 2009;1(1):32-36

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