scholarly journals Inhibition Kinetics of Acetylcholinesterase and Phosphatases by the Active Constituents of Terminalia arjuna and Tamarindus indica in the Cerebral Ganglion of Lymnaea acuminata

2017 ◽  
Vol 9 (2) ◽  
pp. 148-156 ◽  
Author(s):  
Neelam Soni ◽  
Dinesh Kumar Singh ◽  
Vinay Kumar Singh
2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Preetee Jaiswal ◽  
Pradeep Kumar ◽  
V. K. Singh ◽  
D. K. Singh

This study was designed to investigate the effects of molluscicidal components of Myristica fragrans Houtt. (Myristicaceae) on certain enzymes in the nervous tissue of freshwater snail Lymnaea acuminata Lamarck (Lymnaeidae). In vivo and in vitro treatments of trimyristin and myristicin (active molluscicidal components of Myristica fragrans Houtt.) significantly inhibited the acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. The inhibition kinetics of these enzymes indicates that both the trimyristin and myristicin caused competitive noncompetitive inhibition of AChE. Trimyristin caused uncompetitive and competitive/noncompetitive inhibitions of ACP and ALP, respectively whereas the myristicin caused competitive and uncompetitive inhibition of ACP and ALP, respectively. Thus results from the present study suggest that inhibition of AChE, ACP, and ALP by trimyristin and myristicin in the snail Lymnaea acuminata may be the cause of the molluscicidal activity of Myristica fragrans.


2011 ◽  
Vol 54 ◽  
pp. S312 ◽  
Author(s):  
H. Dahari ◽  
N. Barretto ◽  
B.J. Sainz ◽  
J. Guedj ◽  
A.S. Perelson ◽  
...  

2021 ◽  
Author(s):  
Ting He ◽  
lei zhao ◽  
Yan Chen ◽  
Xin Zhang ◽  
Zhuoyan Hu ◽  
...  

The effects of longan seed polyphenols (LSPs) on postprandial glycemic response in mice were investigated, enzyme inhibition kinetics of LSPs against α-amylase were studied using an inhibition assay in vitro,...


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