scholarly journals Profile of Blood Donor Deferrals in a Tertiary Care Centre-Our Institutional Experience

2021 ◽  
pp. 75-80
Author(s):  
D. Rajeswari Thivya ◽  
R. Vijayashree ◽  
K. Meghanath
Keyword(s):  
Blood Donor ◽  
Demographic Data ◽  
Tertiary Care ◽  
Blood Bank ◽  
Care Hospital ◽  
Blood Products ◽  
Tertiary Care Centre ◽  
Donor Pool ◽  
Common Cause ◽  
Donor Deferral

Background:  It is the prime duty of transfusion services to provide safe, adequate and timely need of blood and the blood products. Understanding the reasons for donor deferral can help in planning more efficient recruitment strategies and educate and motivate temporarily deferred donors in order to maintain a safe and adequate supply of blood products. Aims of the Study: To evaluate and analyze the blood donor deferral pattern in a tertiary care hospital blood bank and to review its influence on blood safety. Methodology: This retrospective study was conducted in the blood bank, CHRI from the year January 2015 to December 2018. Data like demographic data, clinical history, physical examination, haematological examination, stored in the blood bank was retrived. The donors will be deferred based on standard WHO guidelines. The collected deferral data was analyzed using SPSS software 2011version 20. Results: During the study period there were 7010 registered blood donors. The deferral rate was 5.19%. Among the donor deferrals, females were more commonly deferred ie 31.66%. The deferral rate among voluntary and replacement donors are 4.71% and 11.62% respectively. The rate of permanent deferral (17.86%) was less compared to temporary deferral (82.14%). Among temporary deferral anaemia is the most common cause (27.75%). Seropositive for Hepatitis B is the most common cause for permenant deferral (52.30%). Conclusion: In our study temporary deferral is higher this necessities the need of education, motivation of these donors for future donation to maintain a healthy and safe donor pool. 

scholarly journals Patterns of pre-donation deferral in voluntary blood donors with its impact on the donor pool- A study in a tertiary care hospital

2021 ◽  
Vol 7 (1) ◽  
pp. 55-59
Author(s):  
Dr. Reshma Anegundi ◽  
◽  
Dr. Divyashree B N ◽  
Keyword(s):  
Blood Transfusion ◽  
Blood Donation ◽  
Tertiary Care ◽  
Vital Signs ◽  
Blood Bank ◽  
Care Hospital ◽  
Donor Pool ◽  
Blood Transfusion Service ◽  
Donor Deferral ◽  
Blood Grouping

Background: The prime responsibility of a Blood Transfusion Service is to provide a very safe,sufficient and timely supply of blood and its components to those in need. In fulfilling thisresponsibility, the Blood Transfusion Service should ensure that the act of blood donation is safe andcauses no harm to the donor. Aims and objectives: To estimate the incidence of pre-donationdeferral in a tertiary care institute and to estimate various factors for donor deferral. Material andmethodology: A retrospective analysis of donors data was collected from January 2019 toDecember 2019 from the donor deferral registry maintained in the blood bank. In this study, thesubjects who visited our blood bank or arrived at a voluntary blood donation camp for purpose ofdonating blood were screened by donor questionnaire and basic physical examination done withrecording vital signs(temperature, blood pressure, pulse rate) followed by hemoglobin estimationand blood grouping. Results: In the present study, 456 donors were deferred from donation. Thedeferral rate was 13.6%. Deferral rate was high among males. The majority of deferrals, weretemporary deferrals, 380(83.33%) and 76(16.66%) were permanent deferrals. Anemia was themost common cause among temporary deferrals constituting 56.05% of temporary deferrals and46.71% of total deferrals. Conclusion: Attempts should be made to create awareness amongpotential donors by conducting health talks, distributing educational pamphlets, counselling donorsduring donation and encouraging them for future donations.

scholarly journals TO ANALYSE THE DEFERRAL INCIDENCE AND ITS PATTERN AMONG THE BLOOD DONORS IN A TERTIARY CARE CENTRE IN NORTH INDIA.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Dr. Surbhi Jain
Keyword(s):  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Selection Process ◽  
Tertiary Care ◽  
Clinical History ◽  
North India ◽  
Tertiary Care Centre ◽  
One Year ◽  
Donor Deferral

Background: Blood donor programme is vital to any transfusion service. This process of blood donation involves voluntary and non remunerated blood donors. The objective of donor screening is to minimize the chances of transmitting infectious agents to recipients. Material and Method: The study was conducted during one year duration from 2017-2018. A total of 700 donors are deferred against 9556 blood donors recruited on the basis of clinical history and brief medical examination in blood bank and voluntary blood donation camps. Donors were deferred temporarily or permanently. Result: Out of 700 deferred donors; 546 were voluntary and 154 were replacement blood donors. Male (601) outnumbered female (99). There were 682 temporary and 18 permanent deferral. Most common age group for deferral was 17-30 yrs (490). Common causes included anemia(142), on medication(108), underweight(83) and high blood pressure(72). Conclusion: Donor selection process is a most important preliminary step in blood banking and should follow stringent medical and regulatory rules. Studying and analysing the profile of blood donors will help to identify sections of the population which could be targeted to increase the pool of voluntary blood donors. Every attempt should be made to decrease the donor deferral keeping in view the safety of both donor and recipients. Keywords: Blood donor, Deferral, Voluntary, Temporary, Permanent.

scholarly journals Impact and outcome of cardiac diseases in pregnancy

2020 ◽  
Vol 10 (1) ◽  
pp. 102
Author(s):  
Gira Dabhi ◽  
Jignesh Chauhan ◽  
Munjal Pandya ◽  
Rahul Sinhar
Keyword(s):  
Heart Disease ◽  
Cardiac Disease ◽  
Nyha Class ◽  
Demographic Data ◽  
Tertiary Care ◽  
Mode Of Delivery ◽  
Close Monitoring ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
In Pregnancy

Background: Present study done to study incidence, effect of pregnancy on cardiac disease and vice-versa and feto-maternal outcome in patients with cardiac disease in pregnancy at tertiary care hospital.Methods: It’s a retrospective observational study conducted in Department of OBGY at tertiary care hospital between 01 June 2019 to 31 May 2020. 28 cases of cardiac disease out of 8659 patients registered included in the study. Demographic data like age, parity, etiological factors of cardiac disease, mode of delivery, neonatal outcome noted from case records.Results: In study, 32% were unregistered cases and 10.7% had never sought any medical care before. Majority (53.6%) cases belonged to 20-25 years. Heart disease noted to be more in primipara (35.7%). 71.4% belonged to NYHA class 1+2 and had a relatively uneventful peripartum period. Majority (53.6%) patients had rheumatic valvular disease. Cases of Congenital heart disease were17.8%, pulmonary artery hypertension was 25%, Maternal mortality were 2(7.2%). 46.5% women delivered with caesarean section. PIH (18%) and anemia (7.2%) were most commonly associated conditions. 85.6% women delivered live newborns and full term, pre-term deliveries and IUGR were 71.4%, 17.8% and 10.7% respectively.Conclusions: Rheumatic origin is the most common cardiac disease associated with pregnancy. The availability of early diagnostic techniques and reference to tertiary care centre, timely admission and close monitoring of patient and delivery with multidisciplinary approach include specialized cardiologic care, high risk obstetric support and neonatology expertise can minimize feto-maternal morbidity and mortality. Pre-conceptional counselling, regular antenatal check-ups and contraceptive advice must be included in counselling part.

A Retrospective Study of Pemphigus in a Tertiary Care Centre in South India

2021 ◽  
Vol 8 (31) ◽  
pp. 2913-2918
Author(s):  
Simon Sheena Ann
Keyword(s):  
Histopathological Examination ◽  
Demographic Data ◽  
Tertiary Care ◽  
Immunosuppressive Treatment ◽  
Care Hospital ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Medical Disorders ◽  
Autoimmune Bullous Diseases ◽  
Mucosal Involvement

BACKGROUND Pemphigus is a group of rare, life-threatening autoimmune bullous diseases of the skin and mucosa which result in intraepidermal blistering. Associated autoimmune conditions and the extensive mucocutaneous detachment impair the quality of life. Immunosuppressive treatment adds to the morbidity in patients. We wanted to assess the clinical presentation of pemphigus among the study subjects along with the outcome of pemphigus patients with the extent of the disease and results of pus culture. METHODS Retrospective analysis of case records of patients with pemphigus in a tertiary care hospital during a period of 3 years was done in 2015. Demographic data, clinical findings, underlying medical disorders, details of deaths, investigation reports and treatment details were recorded. RESULTS Common age group affected was 51-60 years (31.5 %) among a total of 54 pemphigus patients. There were 26 males and 28 (51. 9 %) females and in majority of the patients (44.4 %) duration was less than 6 months. Out of 47 patients, oral mucosal involvement was grade 1 in 20 (37 %) cases, grade 2 in 12 (22.2 %) and in 15 (27.8 %) patients it was grade 3.Histopathological examination showed suprabasal cleft in 82.1 %, subcorneal blister in 5.7 %, acantholytic cells in 48.6 % and row of tombstone appearance in 9.4 %. Out of 36 patients, DIF test reported intercellular IgG in 65 % and C3 in 50 % .Diabetes was found in 14 (25.9 %), candidiasis in 12 (22.2 %), thyroid disease in 6 (11.1 %) and hypertension in 3 patients. Three patients died. Among 10 patients with more than 30 % body surface area involvement, 1 (10 %) patient died. Two (13 %) deaths occurred among 15 patients in whom pus C&S was positive. CONCLUSIONS Pemphigus patients were of slightly higher (51 - 70 years) age group and the 3 patients died were females. Autoimmune disorders like diabetes and thyroid disorders were found among many patients and their family members. Infection could be an important cause of death, but no statistically significant association was found in the present study. KEYWORDS Pemphigus, Steroids, Comorbidity, Deaths

scholarly journals Seroprevalence of markers of transfusion transmissible infections among blood donors at a tertiary care hospital blood bank: a 5 year retrospective study

2019 ◽  
Vol 7 (8) ◽  
pp. 2976
Author(s):  
Irm Yasmeen ◽  
Supinder Kour ◽  
Imran Khurshid ◽  
Aasifa Malik
Keyword(s):  
Blood Donors ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Bank ◽  
Care Hospital ◽  
Serum Samples ◽  
Tertiary Care Centre ◽  
Healthy Donors ◽  
Hiv 1 ◽  
Apparently Healthy

 Background: Transfusion transmitted infections (TTIs) can be caused by various microorganisms present in the blood of apparently healthy donors. The recipient may get infected after being transfused with the unsafe blood. It is mandatory to screen the blood for HIV 1 and 2, HBV, HCV, Syphilis and Malaria. This study was undertaken to investigate the seroprevalance of Transfusion transmitted infections among blood donors at our tertiary care centre and to compare our study with other studies conducted at different hospitals of the country as well as outside.Methods: A retrospective review of blood donor records was made over a period of 5 years with effect from January 2014 to December 2018 at blood bank, department of Blood Transfusion and Immunohaematology, SKIMS, Soura, Srinagar. Both voluntary and replacement blood donors were selected after taking proper history and examination were included in the study. Serum samples were screened for HIV 1 & 2, HBV (HBsAg) and HCV using ELISA with 3rd generation kits.Results: A total of 56325 blood donors were screened. Out of total 55346 (98.2%) were males and 979 (1.73%) were females. Among them 38969 (69.1%) were replacement donors and 17356 (30.8%) were voluntary donors. The seroprevalance of HBV (HBsAg), HCV and HIV 1and 2 was 0.24%, 0.17% and 0.01% respectively and overall seroprevalance of TTIs was 0.43%.Conclusions: Continuous improvement and implementation of newer techniques like NAT and chemilumenescence for testing of blood for TTIs will reduce the risk of acquiring these infections.lance

scholarly journals CUT THROAT INJURY- A CRITICAL EMERGENCY: REVIEW OF 47 CASES IN A TERTIARY CARE CENTRE IN EASTERN INDIA

2020 ◽  
pp. 1-4
Author(s):  
Tithi Debnath ◽  
Jayanta Saha ◽  
Subhadeep Chowdhury
Keyword(s):  
Multidisciplinary Approach ◽  
Tertiary Care ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Rural People ◽  
Common Cause ◽  
Mortality And Morbidity ◽  
Injury Patient ◽  
Zone Ii

Objective: To determine causes behind cut throat injury, analyse the demographics, evaluate treatment, complications, and outcome of cut throat injuries. Methodology: This prospective observational type of study was conducted at a tertiary care hospital during June 2018 to December 2019. A total of 47 cases included in this study. The demographics were recorded, and evaluation of the patient was done as per ATLS protocol. Necessary investigations were performed, and management was done by a team comprised of anaesthetist, otolaryngologist, CTVS surgeon and psychiatrist. After discharge of the patients, follow up was done for 6 months. Results: In our study the M: F is 3.27:1 and 36-50 years age group were mostly affected. Most common cause of injury was suicidal (61.70%). Majority patient had zone II injury (76.6%). 68.09% patients discharged within 8-14 days. Alteration of voice was most common complications (14.9%).61.70% patients are living completely normal life without any morbidity. Mortality rate after admission was 8.51%. Conclusion: Cut throat injury is common in middle aged male and rural people. Suicidal injuries are most common cause behind it. Early planned interventions, multidisciplinary approach, and regular follow up can reduce the mortality and morbidity of the cut throat injury patient.

scholarly journals Frequency and Nature of Transfusion Related Adverse Reactions in Patients Admitted in A Tertiary Care Hospital

2021 ◽  
Vol 33 (1) ◽  
pp. 27-33
Author(s):  
Naylla Islam ◽  
- Amiruzzaman ◽  
Mohammad Ehasun Uddin Khan ◽  
Ashim Chakrabarty ◽  
Md Arifuzzaman ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Fresh Frozen Plasma ◽  
Care Hospital ◽  
Transfusion Reaction ◽  
Blood Products ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Duration Of Storage ◽  
Fresh Frozen ◽  
Transfusion Reactions

Background:Transfusion of blood and blood products if employed safely, with intensive care can save manyvaluable lives. But a number of transfusion reactions may develop that are sometimesmore serious and life threatening.So this study was done to find out the most frequent and life threatening reactions that develop during transfusion. Methods: A Cross sectional descriptive observational study was performed at a tertiary care centre. Patients of 18 years and older irrespective of sexes who received blood and blood products due to different reasons between April 2020 to September 2020 were included in this study. A total of 96 patients were included in the study. Results:In thisstudy 11(11.5%) out of 96 patients had transfusion reactions of different types .Febrile non haemolytic reaction was the highest with 8 patients (8.33%),followed by Allergic reaction in 2 patients(2.08%) and Acute haemolytic transfusion reaction in 1 patient (1.04%).Among them 7(63.6%) reactions occurred with whole blood , 2(18.2%) reactions occurred with red cell concentrate and 1 reaction occurred with Apheresis platelet (9.1%) and fresh frozen plasma(9.1%).Statistically significant association was found between duration of storage of blood and transfusion reaction. Conclusion: Febrile non haemolytic reaction was the commonest type of transfusion reaction found in this study and there was also statistically significant association between duration of storage of blood and transfusion reaction. Bangladesh J Medicine July 2022; 33(1) : 27-33

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