Intensity noise characteristics of intracavity contacted VCSELs with rhomboidal oxide current aperture for the magnetometric sensor with Cs133 vapor cell used in magnetoencephalography

We demonstrate noise characterization of novel 894.4 nm vertical-cavity surface emitting lasers with intracavity contacts and a rhomboidal oxide current aperture (IC-VCSELs), dedicated to 133Cs D1 line compact optically pumped atomic magnetometers (OPM). The laser relative intensity noise, measured to be -139 dB/Hz at 10 kHz frequency in 1 Hz bandwidth for a laser optical power of 0.8 mW, is decreased with optical power growth. The IC-VCSELs polarization-resolved relative intensity noise is 143 dB/Hz at 10 kHz frequency in 1 Hz bandwidth for 0.8 mW. The emission linewidth of the VCSEL is about 55 MHz. The IC-VCSEL parameters are determined, such as emission linewidth ~ 50-60 MHz, optical power ~ 0.5-1.0 mW, at which the polarization-resolved RIN becomes close to the RIN, which makes it possible to use these lasers in various OPM Mz and Mx schemes. The ultimate sensitivity of OPM was estimated by the ratio of the magnetic resonance to the signal to noise level. It is shown that a OPM based on the IC-VCSELs, assuming magnetic resonance FWHM ~ 1 kHz, can achieve a shot noise-limited sensitivity around 20 fT in 1 Hz bandwidth without any polarization improvements by polarizer or polarization beam splitter cube (PBC). Developed IC-VCSELs is acceptable for use in compact OPM for magnetoencephalography.

Estimation of second harmonic generation intensity-noise in random periodically poled lithium niobate

Periodically poled lithium niobate (PPLN) predominantly has a random duty-cycle error (RDE), latent in them by virtue of poling mechanism. This error needs to be quantitatively predicted to abstain from parasitic harmonic generation. In this paper, we have calculated the influence of the RDEs degenerate noise in second-harmonic generation (SHG) consisting of PPLN. Here, we propose a method for calculating the random domain-wall distribution statistics by the SHG. We explored the equivalence between the statistics of random domain distribution by SHG and far-field diffraction pattern method.

Disruption of Glutamate Release and Uptake-Related Protein Expression After Noise-Induced Synaptopathy in the Cochlea

High-intensity noise can cause permanent hearing loss; however, short-duration medium-intensity noise only induces a temporary threshold shift (TTS) and damages synapses formed by inner hair cells (IHCs) and spiral ganglion nerves. Synaptopathy is generally thought to be caused by glutamate excitotoxicity. In this study, we investigated the expression levels of vesicle transporter protein 3 (Vglut3), responsible for the release of glutamate; glutamate/aspartate transporter protein (GLAST), responsible for the uptake of glutamate; and Na+/K+-ATPase α1 coupled with GLAST, in the process of synaptopathy in the cochlea. The results of the auditory brainstem response (ABR) and CtBP2 immunofluorescence revealed that synaptopathy was induced on day 30 after 100 dB SPL noise exposure in C57BL/6J mice. We found that GLAST and Na+/K+-ATPase α1 were co-localized in the cochlea, mainly in the stria vascularis, spiral ligament, and spiral ganglion cells. Furthermore, Vglut3, GLAST, and Na+/K+-ATPase α1 expression were disrupted after noise exposure. These results indicate that disruption of glutamate release and uptake-related protein expression may exacerbate the occurrence of synaptopathy.