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2022 ◽  
pp. 1468795X2110674
Author(s):  
Sam Whimster

In May 1904 Max Weber published a short article in the Frankfurter Zeitung. It has gone unnoticed in the extensive Weber literature and it appears here in English translation for the first time. It is an important statement of Weber’s political views after his withdrawal from his active political engagement in the 1890s. He defends the Reich Constitution from attack and a possible coup d’état. He demands that the German Parliament (Reichstag) stand up to autocratic plans, closely linked to Emperor William II, to suppress democracy and voting rights. A constitutional conflict would require not a great statesman but an ‘unscrupulous idiot or a political adventurer’ who would undermine ‘all our institutions and the security of law for many generations’. The article marks the start (earlier than previously assumed in the literature) of Weber’s consistent championing of Parliament and democratic institutions.


Author(s):  
Shirish Ravan ◽  
Tom De Groeve ◽  
Lara Mani ◽  
Einar Bjorgo ◽  
Richard Moissl ◽  
...  

Abstract Near-Earth object (NEO) impact is one of the examples of high impact and low probability (HILP) event, same as the Covid-19 pandemic the world faces since the beginning of 2020. The 7th Planetary Defense Conference held by the International Academy of Astronautics (IAA) in April 2021 included an exercise on a hypothetical NEO impact event, allowing the planetary defense community to discuss potential responses. Over the span of the 4-day conference this exercise connected disaster response and management professionals to participate in a series of panels, providing feedback and perspective on the unfolding crisis scenario. The hypothetical but realistic asteroid threat scenario illustrated how such a short-warning threat might evolve. The scenario utilized during the conference indicates a need to prepare now for what might come in the future, because even with advance notice, preparation time might be minimal. This scenario chose Europe for the impact, which may likely cope with such a disaster, through the Union Civil Protection Mechanism (UCPM) and other solidarity and support mechanisms within the European Union (EU), as well as with potential support from international partners. This short article raises concern about other areas in the world on how they may access NEO impact information and cope with such disasters. It also provides an idea on vast scale of such disaster vis-à-vis the current capacity of response systems to cope with a larger event in Europe or elsewhere. This scenario showed that planetary defense is a global endeavor. Constant engagement of the planetary defense and disaster response communities is essential in order to keep the world safe from potential disasters caused by NEO impacts.


2021 ◽  
Vol 9 (4) ◽  
pp. 236-245
Author(s):  
Mohammad Ali Heidari-Shahreza

This research note brings readers’ attention to an extensive, ongoing research project named Humour-Integrated Language Learning (HILL). The project investigates HILL as an innovative approach to language education and humour literacy. Within the limits of this short article, HILL is initially conceptualised, and then, an outline of the project is provided. Then, I describe ongoing lines of the research, giving a snapshot of the preliminary results. Finally, future directions of the HILL project are elaborated on.


Author(s):  
Craig Heller

The words “regulation” and “control” have different meanings. A rich literature exists on the control mechanisms of sleep—the genomic, molecular, cellular, and circuit processes responsible for arousal state changes and characteristics. The regulation of sleep refers to functions and homeostatic maintenance of those functions. Much less is known about sleep regulation than sleep control, largely because functions of sleep are still unknown. Regulation requires information about the regulated variable that can be used as feedback information to achieve optimal levels. The circadian timing of sleep is regulated, and the feedback information is entraining stimuli such as the light–dark cycle. Sleep itself is homeostatically regulated, as evidenced by sleep deprivation experiments. Eletroenceophalography (EEG) slow-wave activity (SWA) is regulated, and it appears that adenosine is the major source of feedback information, and that fact indicates an energetic function for sleep. The last aspect of sleep regulation discussed in this short article is the non-rapid eye movement (NREM) and rapid eye movement (REM) sleep cycling. Evidence is discussed that supports the argument that NREM sleep is in a homeostatic relationship with wake, and REM sleep is in a homeostatic relationship with NREM sleep.


Pathogens ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1641
Author(s):  
Ming Tan

Noroviruses are the major viral pathogens causing epidemic and endemic acute gastroenteritis with significant morbidity and mortality. While vaccines against norovirus diseases have been shown to be of high significance, the development of a broadly effective norovirus vaccine remains difficult, owing to the wide genetic and antigenic diversity of noroviruses with multiple co-circulated variants of various genotypes. In addition, the absence of a robust cell culture system, an efficient animal model, and reliable immune markers of norovirus protection for vaccine evaluation further hinders the developmental process. Among the vaccine candidates that are currently under clinical studies, recombinant VP1-based virus-like particles (VLPs) that mimic major antigenic features of noroviruses are the common ones, with proven safety, immunogenicity, and protective efficacy, supporting a high success likelihood of a useful norovirus vaccine. This short article reviews the recent progress in norovirus vaccine development, focusing on those from recent clinical studies, as well as summarizes the barriers that are being encountered in this developmental process and discusses issues of future perspective.


Author(s):  
John Dickson ◽  
Uta Eberlein ◽  
Michael Lassmann

Abstract Aim Recent advancements in PET technology have brought with it significant improvements in PET performance and image quality. In particular, the extension of the axial field of view of PET systems, and the introduction of semiconductor technology into the PET detector, initially for PET/MR, and more recently available long-field-of-view PET/CT systems (≥ 25 cm) have brought a step change improvement in the sensitivity of PET scanners. Given the requirement to limit paediatric doses, this increase in sensitivity is extremely welcome for the imaging of children and young people. This is even more relevant with PET/MR, where the lack of CT exposures brings further dose reduction benefits to this population. In this short article, we give some details around the benefits around new PET technology including PET/MR and its implications on the EANM paediatric dosage card. Material and methods  Reflecting on EANM adult guidance on injected activities, and making reference to bed overlap and the concept of MBq.min bed−1 kg−1, we use published data on image quality from PET/MR systems to update the paediatric dosage card for PET/MR and extended axial field of view (≥ 25 cm) PET/CT systems. However, this communication does not cover the expansion of paediatric dosing for the half-body and total-body scanners that have recently come to market. Results In analogy to the existing EANM dosage card, new parameters for the EANM paediatric dosage card were developed (class B, baseline value: 10.7 MBq, minimum recommended activity 10 MBq). The recommended administered activities for the systems considered in this communication range from 11 MBq [18F]FDG for a child with a weight of 3 kg to 149 MBq [18F]FDG for a paediatric patient weight of 68 kg, assuming a scan of 3 min per bed position. The mean effective dose over all ages (1 year and older) is 2.85 mSv. Conclusion With this, recommendations for paediatric dosing are given for systems that have not been considered previously.


2021 ◽  
Vol 152 (A2) ◽  
Author(s):  
D Andrews

As part of writing a short article entitled “Ship Design – From Art to Science?” [1] for the Institution’s 150th anniversary celebratory volume [2], the author consulted the Institution’s centenary book by K C Barnaby [3] to get a feel for the formative first hundred years of ship design recorded in the learned papers presented to the Institution. This consultation was motivated by consideration of the papers in the first volume of the Transactions of 1860, which, surprisingly, contained no papers directly on ship design, either on ship design in general or through describing the design intent behind a specific new ship. Rather, like the very first paper by Reverend J Woolley, the remaining 1860 papers concerned themselves with what could be called the application of science (and mathematics) to the practice of naval architecture as an engineering discipline. However this initial focus broadened out in subsequent volumes of the Transactions so that both technical descriptions of significant new ship designs and, more recently, papers on the general practice of ship design have also figured, alongside the presentation of progress in the science of naval architecture. Given that the vast bulk of ships built over this period have been designed like most buildings to a set pattern, or as we naval architects would say based on a (previous) “type ship”, those designs presented in the Institution’s Transactions, and the few other collections of learned societies’ papers, are largely on designs that have been seen to be of particular merit in their novelty and importance. Therefore this review looks at the developments in ship design by drawing on those articles in the Transactions that are design related. In doing so the papers have been conveniently broken down into the three, quite momentous, half centuries over which the Institution has existed. From this historical survey, it is then appropriate to consider how the practice of ship design may develop in the foreseeable future.


2021 ◽  
Vol 46 (2) ◽  
pp. 20-25
Author(s):  
Christopher Peace ◽  
Pippi Priestley-King

Occupational health and safety (OHS) practitioners need to understand prosecutions that have been before the District Court if they are to provide informed guidance about compliance with the New Zealand (NZ) Health and Safety at Work Act (HSWA) to “persons having control of a business or undertaking” (PCBUs). However, if they cannot access academic databases, they may need to rely on individual reports of a few cases but may not have the time or resources to develop their own database. Those who are studying for a tertiary level qualification may also lack the time to find and catalogue more than a few cases. This short article reports on the first stage of the development and analysis of a dataset of prosecutions under NZ OHS legislation. We describe our data sources and a high-level analysis of the dataset and issues to be resolved before proceeding with further data analysis. This work also forms part of research into “grey literature” and its use in practice by OHS practitioners and professionals. We conclude by showing the disparity between prosecutions and deaths due to occupational disease and trauma (leading to an area for further research) and loop back to one of the origins for this research: the meaning of a safe system of work.


2021 ◽  
Vol 34 (4) ◽  
pp. 515-516
Author(s):  
Borros Arneth

The purpose of this short article is the question if or not we are moving through space with a gamma factor of 1 or if we already have a different gamma factor. For this question, the experimental masses of the electron and proton are compared with the theoretically derived values. For the calculation of the particle masses, the newly derived resonance formula is used.


2021 ◽  
Vol 20 (1) ◽  
pp. 149-153
Author(s):  
Ruxandra Vişan

Abstract Placed at the interface between metalexicography and gender studies, this short article discusses issues concerning gender representations in present-day dictionaries. Evoking recent controversies regarding the representation of gender-related terms such as “cisgender” or “woman” in The Oxford English Dictionary, the essay goes on to discuss the prescriptive/descriptive opposition concerning lexicographical representations, taking its cue from previous approaches, which suggest re-envisaging the prescriptive/descriptive dyad as a continuum (Straaijer, 2009; Wilton 2014), or replacing this traditional binary model with a nonbinary approach (Nossem, 2018; Turton, 2020).


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