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2022 ◽  
Vol 7 (5) ◽  
pp. 8-15
Author(s):  
R. R. Alimova ◽  
V. V. Yakovleva

In the article, a metaphor as a universal category of thinking, a special cognitive analogy-based operation, and a method of modeling reality, is investigated on journalistic materials of modern Spanish media discourse, the online version of the Spanish newspaper EL MUNDO in particular from the discursive point of view. The use of various types of metaphors by Spanish politicians, which are part of the national-linguistic picture of the world, is examined on the example of media materials concerning the most significant events in the internal life of Spain and international community. Based on the classification by A.P. Chudinov, a semantic and quantitative analysis of metaphorical models in Spanish media discourse is carried out. It is concluded that at the time being Spanish political discourse abounds predominantly in anthropomorphic and sociomorphic metaphors. It was also found that the most frequent is the use of morbial metaphors, which reflect the crisis the Spanish society is undergoing in the pandemic period and its economic, political and social impact on the life of modern Spanish society.


2022 ◽  
Vol 0 (45) ◽  
pp. 248-286
Author(s):  
Qasem Mohammed Helal Saleem ◽  

The present study discusses the significant role of the historical memory in all the Spanish society aspects of life. When a novelist takes the role and puts on the mask of one of the novel’s protagonists or hidden characters, his memory of the events becomes the keywords of accessing the close-knit fabric of society and sheds lights on deteriorating social conceptions in a backwards social reality that rejects all new progressive ideas and modernity. Through concentrating on the society flawing aspects and employing everything of his stored memory, the author uses sarcasm to criticize and change such old deteriorating reality conceptions. Through reminding his community of the glories of their ancestors’ bright legacy, Cela’s work could be considered a wakeup call to bring life to, to revive the remains of the past and to save his country from the horror and miseries of the wars. Hence, the present study stresses all the author’s teachings and constant lessons reflecting and filling the novel with symbols of the Spanish patriotism. Resumen En esta investigación discutimos el gran e importante papel de la memoria histórica en todos los aspectos de la vida de la sociedad española, ya que el propio autor encarnaba a uno de los protagonistas de la novela a través de su memoria o llevaba la máscara de uno de los personajes de la novela. Personajes ocultos, pues su memoria de los hechos representó la clave para acceder a ese tejido social entrelazado, arrojó luz sobre muchos conceptos atrasados ​​a la luz de una realidad social en deterioro, que vive lejos de la cultura y el conocimiento, y carece de lógica en su comportamiento, e incluso no quiere conocer ni siquiera tratar nuevas ideas que pidan desarrollo o lo que se llama modernidad. El autor empleó todo lo que almacenaba su memoria en criticar esa realidad, con el fin de cambiar algunos de los conceptos a los que estaba acostumbrado durante largas épocas, presentando las situaciones e imágenes miserables y vergonzosas de esa sociedad, además de utilizar frases mezcladas con ironía. El trabajo de Cela fue como un grito para despertar a la comunidad, ya que presentamos sus muchos intentos de revivir los restos del pasado que podrían beneficiar a su sociedad, y brindarles respuestas y consejos para salir de esa realidad deterioro, además de salvar a su país de los horrores y miserias de la guerra, recordándole las grandes actitudes y elevados valores que narran las glorias de sus antepasados ​​y su gran herencia. Por tanto, nuestro foco en esta investigación estuvo en aquellas lecciones y sermones que fueron repetidos por el autor en fórmulas que sugieren y portan simbólicos que reflejan los significados de pertenencia y la identidad nacional española que llenaron las páginas de la novela.


2021 ◽  
Vol 15 (3) ◽  
pp. 191-192
Author(s):  
Ramón Viladot-Pericé ◽  
Antonio Viladot Voegeli

Hallux rigidus (HR) represents one of the most frequent forefoot disorders, together with hallux valgus and lateral toe deformities, being the most frequent degenerative process in the foot and ankle.This publication is the result of the collaboration of colleagues of the Spanish Society of Medicine and Foot and Ankle Surgery (Sociedad Española de Medicina y Cirugía del Pie y Tobillo, SEMCPT) and the Argentinean Society of Medicine and Foot and Leg Surgery (Sociedad Argentina de Medicina y Cirugía de Pie y Pierna, SAMCPP). It is an honor for us to have this work edited in the Journal of the Foot & Ankle, a journal with a marked Latin identity. We really thank Alexandre Leme Godoy-Santos, Chairman of the Editorial Board, for his help and contribution. This update topic has been coordinated by R. Viladot Pericé and A. Viladot Voegeli, together with M. Herrera and M. Núñez-Samper.Considering the interest and the extent of this topic and, according to the coordinators, we have divided the publication into two parts. The first one describes general aspects (definition, etiology, classification, treatment algorithm, etc.) and the conservative treatment of HR, whereas the second one addresses the different surgical techniques described to treat this disease.The aim of this work is to review our knowledge on HR and to perform an update on the innovations that have emerged during the last years.


Author(s):  
Vanessa Roger-Monzó ◽  
Yolanda Cabrera-García-Ochoa ◽  
Carolina Moreno-Castro

The essential elements of the Spanish press’s discourse on nutrition guidelines during the Covid-19 health crisis are identified. To do this, the evolution of media representation is examined, with a semantic analysis of the news appearing in the national media in Spanish regarding nutrition and Covid-19. The analyzed period is from 31 January 2020 to 31 January 2021. The content search carried out using the Factiva database identified 117 records, which were analysed using T-LAB software. The results reveal that the press warned of hoaxes regarding nutrition during the study period. Four semantic groups are identified, informing about the most appropriate eating patterns according to the different circumstances during the pandemic. The results show that the press plays a role as an educator of Spanish society on nutrition-related topics. Resumen Se identifican los elementos esenciales sobre el discurso que la prensa española llevó a cabo sobre las pautas de nutrición durante la crisis sanitaria de la Covid-19. Se examina la evolución de la representación mediática y se efectúa un análisis semántico de las noticias aparecidas en los medios nacionales y en lengua española referidas a la nutrición y la Covid-19. El período analizado se inició el 31 de enero de 2020 y finalizó el 31 de enero de 2021. La búsqueda de contenidos se realizó mediante la base de datos Factiva. Se obtuvieron 117 registros que se analizaron mediante el software T-LAB. Los resultados revelan que la prensa alerta de los bulos sobre nutrición que se han producido durante el período analizado. Se identifican cuatro grupos semánticos orientados a informar sobre las pautas de alimentación más adecuadas según las diferentes circunstancias en la pandemia. Se constata que la prensa desempeña su papel como agente educador en la sociedad en materia de nutrición.


2021 ◽  
pp. 127-138
Author(s):  
Pilar BLANCO MIGUEL ◽  
Yolanda BORREGO ALÉS

Although in recent years a whole series of measures and programmes have been carried out with the aim of having an impact on the situations of discrimination and racism in which the Romani population is immersed, the results obtained allow us to surmise that, although there has been some progress, the situation has not entirely changed. A stereotyped view of the Romani population still exists in some parts of Spanish society, meaning that this community continues to be immersed in a profound process of social exclusion. Objectives of research are to demonstrate whether there are situations of discrimination in the Huelva Roma population, as well as to know the areas in which these acts of discrimination are carried out. A qualitative method was chosen. The technique used was an in-depth interview, to allow us to understand the perspective of the professionals who work with this group. In general, we have seen how situations of discrimination against the Romani population persist. These situations extend to different spheres of life, and whose factors respond to a multiplicity of causes. There is a need for significant, long-lasting change. This means it is necessary both to change the processes of social intervention and to involve the Romani community itself, as without their collaboration and legitimacy any intervention will lack future perspective.


2021 ◽  
Vol 32 (23-24) ◽  
pp. 1425-1426
Author(s):  
Gloria González Aseguinolaza ◽  
Ander Izeta ◽  
Francisco Martin Molina

Pharmaceutics ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2036
Author(s):  
Paula Soria-Chacartegui ◽  
Gonzalo Villapalos-García ◽  
Luis A. López-Fernández ◽  
Marcos Navares-Gómez ◽  
Gina Mejía-Abril ◽  
...  

Among cancer patients treated with fluoropyrimidines, 10–40% develop severe toxicity. Polymorphism of the dihydropyrimidine dehydrogenase (DPYD) gene may reduce DPD function, the main enzyme responsible for the metabolism of fluoropyrimidines. This leads to drug accumulation and to an increased risk of toxicity. Routine genotyping of this gene, which usually includes DPYD *HapB3, *2A, *13 and c.2846A > T (D949V) variants, helps predict approximately 20–30% of toxicity cases. For DPD intermediate (IM) or poor (PM) metabolizers, a dose adjustment or drug switch is warranted to avoid toxicity, respectively. Societies such as the Spanish Society of Pharmacogenetics and Pharmacogenomics (SEFF), the Dutch Pharmacogenetics Working Group (DPWG) or the Clinical Pharmacogenetics Implementation Consortium (CPIC) and regulatory agencies (e.g., the Spanish Medicines Agency, AEMPS) already recommend DPYD routine genotyping. However, the predictive capacity of genotyping is currently still limited. This can be explained by the presence of unknown polymorphisms affecting the function of the enzyme. In this case-control work, 11 cases of severe fluoropyrimidine toxicity in patients who did not carry any of the four variants mentioned above were matched with 22 controls, who did not develop toxicity and did not carry any variant. The DPYD exome was sequenced (Sanger) in search of potentially pathogenic mutations. DPYD rs367619008 (c.187 A > G, p.Lys63Glu), rs200643089 (c.2324 T > G, p.Leu775Trp) and rs76387818 (c.1084G > A, p.Val362Ile) increased the percentage of explained toxicities to 38–48%. Moreover, there was an intronic variant considered potentially pathogenic: rs944174134 (c.322-63G > A). Further studies are needed to confirm its clinical relevance. The remaining variants were considered non-pathogenic.


2021 ◽  
Vol 10 (23) ◽  
pp. 5566
Author(s):  
Emilio Bouza ◽  
Arístides de Alarcón ◽  
María Carmen Fariñas ◽  
Juan Gálvez ◽  
Miguel Ángel Goenaga ◽  
...  

This is a consensus document of the Spanish Society of Cardiovascular Infections (SEICAV), the Spanish Society of Thoracic and Cardiovascular Surgery (SECTCV) and the Biomedical Research Centre Network for Respiratory Diseases (CIBERES). These three entities have brought together a multidisciplinary group of experts that includes anaesthesiologists, cardiac and cardiothoracic surgeons, clinical microbiologists, infectious diseases and intensive care specialists, internal medicine doctors and radiologists. Despite the clinical and economic consequences of sternal wound infections, to date, there are no specific guidelines for the prevention, diagnosis and management of mediastinitis based on a multidisciplinary consensus. The purpose of the present document is to provide evidence-based guidance on the most effective diagnosis and management of patients who have experienced or are at risk of developing a post-surgical mediastinitis infection in order to optimise patient outcomes and the process of care. The intended users of the document are health care providers who help patients make decisions regarding their treatment, aiming to optimise the benefits and minimise any harm as well as the workload.


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