Cost-benefit evaluation of management strategies for an invasive amphibian with a stage-structured model

Management strategies for invasive populations should be designed to maximise efficacy and efficiency, i.e. to accomplish their goals while operating with the least resource consumption. This optimisation is often difficult to achieve in stage-structured populations, because costs, benefits and feasibility of removing individuals may vary with stage. We use a spatially-explicit stage-structured model to assess efficacy of past, present and alternative control strategies for invasive guttural toads, Sclerophrys gutturalis, in Cape Town. The strategies involve removal of variable proportions of individuals at different life-history stages and spatial scales. We also quantify the time necessary to implement each strategy as a proxy of financial resources and we correct strategy outcomes by implementation of time to estimate efficiency. We found that the strategy initially pursued in Cape Town, which did not target any specific stage, was less efficient than the present strategy, which prioritises adult removal. The initial strategy was particularly inefficient because it did not reduce the population size despite allocating consistent resources to remove eggs and tadpoles. We also found that such removal might be detrimental when applied at high levels. This counter-intuitive outcome is due to the ‘hydra effect’: an undesired increase in population size caused by removing individuals before overcompensatory density dependence. Strategies that exclusively remove adults ensure much greater management efficiency than those that also remove eggs and tadpoles. Available management resources should rather be allocated to increase the proportion of adult guttural toads that are removed or the spatial extent at which this removal is pursued.

Benefit Evaluation of Real Estate Industry Based on SBM Model

According to the situation of real estate industry in different provinces and cities, the benefit is different, and the benefit of real estate industry in some regions is low. Based on the statistical data of real estate industry in various regions, this paper selects nine indicators, such as the number of enterprises, the average number of employees, the land purchase area (10000 square meters) in this year, to evaluate and analyze the benefit of real estate industry in 31 regions of China by using two-stage super efficiency model. The results show that the input-output of the real estate industry in 17 regions is effective, and the remaining 14 regions are DEA ineffective. The reasons for the inefficiency of the input-output are analyzed, and some suggestions to improve the efficiency are given.

Paroxysmal Nocturnal Hemoglobinuria in the Context of a Myeloproliferative Neoplasm: A Case Report and Review of the Literature

Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by intravascular hemolytic anemia and thrombosis and is notoriously associated with aplastic anemia and myelodysplastic syndromes. Rarer associations include myeloproliferative neoplasms (MPNs), which are also burdened by increased thrombotic tendency. The therapeutic management of this rare combination has not been defined so far. Here, we describe a 62-year-old man who developed a highly hemolytic PNH more than 10 years after the diagnosis of MPN. The patient started eculizumab, obtaining good control of intravascular hemolysis but without amelioration of transfusion-dependent anemia. Moreover, we performed a review of the literature regarding the clinical and pathogenetic significance of the association of PNH and MPN. The prevalence of PNH clones in MPN patients is about 10%, mostly in association with JAK2V617F-positive myelofibrosis. Thrombotic events were a common clinical presentation (35% of subjects), sometimes refractory to combined treatment with cytoreductive agents, anticoagulants, and complement inhibitors. The latter showed only partial effectiveness in controlling hemolytic anemia and, due to the paucity of data, should be taken in consideration after a careful risk/benefit evaluation in this peculiar setting.

Benefit Evaluation Model of Prefabricated Buildings in Seasonally Frozen Regions

In order to effectively develop the benefit evaluation model of prefabricated houses in seasonal frozen soil areas, and improve the comprehensive benefits of prefabricated buildings, this paper proposes a life cycle benefit evaluation model for prefabricated buildings in seasonally frozen regions. According to the climatic characteristics of the area, the impact of the seasonally frozen regions is listed as an evaluation index in the construction stage for comprehensive analysis. The 16 indicators that affect the comprehensive benefits of prefabricated buildings are grouped by the nearest neighbor element analysis method. Fuzzy cluster analysis and analytic hierarchy process are used to filter out the most influential index group to calculate the index weight. Then the model proposed in this paper is compared with the existing model to test the validity of the model. The research results show that research and development costs weight is 0.23, design cost weight is 0.10, construction cost weight is 0.22, resource consumption weight is 0.25, building demolition cost weight is 0.04, and seasonal freezing effect weight is 0.16. The calculation result passed the consistency test and the expert scoring result conformed to the normal distribution, which proved the accuracy of the conclusion. It is proposed that the calculation result of the comprehensive benefit score of the model is 1.8% lower than the previous results, which proves the validity of the model. The model can speed up the efficiency of comprehensive benefit evaluation of prefabricated buildings thereby improving the development level of prefabricated buildings.