Future ethical implications and potential health consequences of nanotechnology research in Jordan: A scientometric analysis

Purpose: To evaluate the implanted legislation and regulations in Jordan, in order to minimize nanotechnology research-related health concerns. Methods: In the first part, all nanotechnology published research in Scopus database and the Jordanian National Database for Researchers were mined. The growth in nanotechnology research was analyzed by calculating the relative growth rate (RGR), doubling time (DT), and compound annual growth rate (CAGR). Thereafter, the results were compared to global preferences. Furthermore, this research explored all possible factors that may influence decision-makers and health policies in Jordan. Results: Data analysis showed that the quantity of nanotechnology research in Jordan is exponentially increasing with RGR (1.96), DT (0.37), and CAGR (33 %) very close to the figures obtained worldwide. The trend line analysis (R2 = 0.9638) expected that more than 65 % of nanotechnology research will be produced within the next 5 years. Moreover, no legislation has been adapted in Jordan to regulate nanotechnology research and industry. Conclusions: Adopting nanotechnology without having any corresponding legislation constitutes a violation of the ethical codes of research, and ignorance of public safety. Moreover, the research suggests a set of steps to organize the crafting of nanotechnology and research in Jordan, and other similar contexts in developing countries.

Towards responsible science and technology: How nanotechnology research and development is shaping risk governance practices in Australia

Incorporating perspectives of multiple stakeholders concerning the appropriate balance of risks and benefits of new and potentially disruptive technologies is thought to be a way of enhancing the societal relevance and positive impacts of those technologies. A risk governance approach can be instrumental in achieving balance among diverse stakeholders, as it enables decision-making processes informed by multiple dimensions of risk. This paper applies a risk governance approach to retrospectively examine the development of nanotechnology research and development (R&D) in Australia to identify how risk governance is reflected in the practices of a range of stakeholders. We identify ten risk-related challenges specific to nanotechnology R&D based on a review of the international literature, which provided the foundation for documenting how those working in the Australian nanotechnology sector responded to these global risk-related challenges. This case study research draws on a range of sources including literature review, semi-structured interviews, and a combination of qualitative and quantitative approaches for data analysis to identify key themes and generate visualisations of the interconnections that exist between risk governance practices. The ability to visualise these interconnections from the qualitative data is a key contribution of this research. Our findings show how the qualitative insights and professional experiences of nanotechnologists provide evidence of how risk governance approaches have been operationalised in the Australian nanotechnology R&D sector. The findings generate three important insights. First, the risk research undertaken by Australian nanotechnologists is interdisciplinary and involves multiple stakeholders from various disciplines and sectors. Unlike traditional risk governance approaches, our findings document efforts to assess, not only physical risks, but also social and ethical risks. Second, nanotechnology risk governance is a non-linear process and practices undertaken to address specific challenges occurred concurrently with and contributed to addressing other challenges. Third, our findings indicate that applying a risk governance approach enables greater intersection and collaboration, potentially bridging any disconnect between scientists, policymakers, and the public to realise transdisciplinary outcomes. This research highlights opportunities for developing systematic methodologies to enable more robust risk governance of other new and emerging technologies.

New progress in international nanotechnology research in the past ten years – visual analysis based on CitesSpace

With the continuous development of high-tech industry, Moore’s law is close to the limit. People urgently need nano science and technology to trigger a new scientific and technological revolution to meet the needs of life, military and so on. Nanotechnology covers almost all industries and has made achievements in the industries such as medical, materials, manufacturing, and information technology. It has changed the production and life of human beings and subverted many industries. In recent years, more and more people have conducted data mining on nanotechnology research. By combing the literature, this paper summarizes the core authors, keyword changes, important authors and emergent words of the existing literature. Contributing to analyzing the research status of this field and revealing research hotspots in this field. It is of great significance for scholars to sort out the development process of nano field and predict the future development trend. Using CitesSpace bibliometric analysis software, 44002 pieces of literature about nanotechnology in SCI and SSCI journals in the core collection of the Web of Science database were analyzed in this paper. The results indicated that countries such as the United States, Germany, China, and Japan have issued more articles; However, the centrality of articles published in European countries such as the UK, Germany, and France was relatively strong; High-yield units mainly included Chinese Acad Sci and Russian Acad Sci; The main research scholars were Wei Wang, Peixuan Guo, Thomas J Webster, Hao Yan; Research emergent words primarily included polymer, particle, dynamics, mechanical properties and silver nanoparticle. On this basis, countermeasure suggestions and prospects are proposed.

Global Trends in Cancer Nanotechnology: A Qualitative Scientific Mapping Using Content-Based and Bibliometric Features for Machine Learning Text Classification

This study presents a new way to investigate comprehensive trends in cancer nanotechnology research in different countries, institutions, and journals providing critical insights to prevention, diagnosis, and therapy. This paper applied the qualitative method of bibliometric analysis on cancer nanotechnology using the PubMed database during the years 2000–2021. Inspired by hybrid medical models and content-based and bibliometric features for machine learning models, our results show cancer nanotechnology studies have expanded exponentially since 2010. The highest production of articles in cancer nanotechnology is mainly from US institutions, with several countries, notably the USA, China, the UK, India, and Iran as concentrated focal points as centers of cancer nanotechnology research, especially in the last five years. The analysis shows the greatest overlap between nanotechnology and DNA, RNA, iron oxide or mesoporous silica, breast cancer, and cancer diagnosis and cancer treatment. Moreover, more than 50% of the information related to the keywords, authors, institutions, journals, and countries are considerably investigated in the form of publications from the top 100 journals. This study has the potential to provide past and current lines of research that can unmask comprehensive trends in cancer nanotechnology, key research topics, or the most productive countries and authors in the field.

Near-Infrared-Triggered Upconverting Nanoparticles for Biomedicine Applications

Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under near-infrared (NIR) light, the last decade has shown a sharp progress in their biomedicine applications. Advances in the techniques for polymer, dye, and bio-molecule conjugation on the surface of the nanoparticles has further expanded their dynamic opportunities for optogenetics, oncotherapy and bioimaging. In this account, considering the primary benefits such as the absence of photobleaching, photoblinking, and autofluorescence of UCNPs not only facilitate the construction of accurate, sensitive and multifunctional nanoprobes, but also improve therapeutic and diagnostic results. We introduce, with the basic knowledge of upconversion, unique properties of UCNPs and the mechanisms involved in photon upconversion and discuss how UCNPs can be implemented in biological practices. In this focused review, we categorize the applications of UCNP-based various strategies into the following domains: neuromodulation, immunotherapy, drug delivery, photodynamic and photothermal therapy, bioimaging and biosensing. Herein, we also discuss the current emerging bioapplications with cutting edge nano-/biointerfacing of UCNPs. Finally, this review provides concluding remarks on future opportunities and challenges on clinical translation of UCNPs-based nanotechnology research.