Given the mutual information of finite-alphabet inputs cannot be calculated concisely and accurately over fading channels, this paper proposes a new method to calculate the mutual information. First, the applicability of the saddle point method is studied, and then the mutual information is estimated by the saddle point approximation method with known channel state information. Furthermore, we induce the expectation of mutual information over doubly correlated multiple-input multiple-output (MIMO) Rayleigh fading channels. The validity of the saddle point approximation method is verified by comparing the numerical results of the Monte Carlo method and the saddle point approximation method under different doubly correlated MIMO fading channel scenarios.