Systemic lupus erythematosus or SLE is a chronic autoimmune disorder of multiple systems that affects blood vessels and connective tissues. Children with SLE generally have a more severe and aggressive disease course than patients with adult-onset disease.
Assess the hematological manifestations of systemic lupus erythematosus (SLE), amely leucopenia, thrombocytopenia, anaemia-with special reference to autoimmune haemolytic naemia (AIHA). Co-relation among different antibodies and clinical and hematological findings
In-patients and Out-patients Department (OPD) of Paediatric Medicine, and out-patient Department (OPD) of Dept. of Rheumatology IPGME&R and SSKM Hospital, Kolkata 700020, a tertiary care center in West Bengal. Period of study-1.5 years (February 2018-July 2019). Inpatient Department and Out patient Department(OPD) of Department of Paediatric Medicine, IPGMER& SSKM Hospital. Depending upon the previous records, available patients eligible for the study , 30 patients were taken as study population. Definition of population- Children upto 12 years of age, attending the Department of Paediatric Medicine of IPGME&R and SSKM Hospital, who were diagnosed cases of Systemic Lupus Erythematosus satisfying inclusion and exclusion criteria for this study.
Lupus nephritis was seen in more than half of the pediatric SLE cases. Larger number of study population needed to find statistically significant association between different parameters in this study