In order to realize robot-assisted spinal laminectomy surgery and meet the clinical needs of the robot workspace, including accuracy in human–robot collaboration, an asymmetrical 3-DOF spatial translational robot is proposed, which can realize spinal laminectomy in a fixed posture. First, based on the screw theory, the constraint screw system of the robot was established, and the degree of freedom was derived to verify the spatial translational ability of the robot. Then, a kinematic model of the robot was established, and a static force model of the robot was derived based on the kinematic model. The mathematical relationship between the external force and the joint force/torque was obtained, with the quality of all links considered in the model. Finally, we modeled the robot and imported it into ADAMS to obtain the static force simulation results of the 3D model. The force error was approximately 0.001 N and the torque error was approximately 0.0001 N∙m compared with the simulation results of the mathematical model, accounting for 1% of the joint force/torque, which is acceptable. The result also showed the correctness of the mathematical models, and provides a theoretical basis for motion control and human–robot collaboration.