MSC-Net: Multitask Learning Network for Retinal Vessel Segmentation and Centerline Extraction

Automatic segmentation and centerline extraction of blood vessels from retinal fundus images is an essential step to measure the state of retinal blood vessels and achieve the goal of auxiliary diagnosis. Combining the information of blood vessel segments and centerline can help improve the continuity of results and performance. However, previous studies have usually treated these two tasks as separate research topics. Therefore, we propose a novel multitask learning network (MSC-Net) for retinal vessel segmentation and centerline extraction. The network uses a multibranch design to combine information between two tasks. Channel and atrous spatial fusion block (CAS-FB) is designed to fuse and correct the features of different branches and different scales. The clDice loss function is also used to constrain the topological continuity of blood vessel segments and centerline. Experimental results on different fundus blood vessel datasets (DRIVE, STARE, and CHASE) show that our method can obtain better segmentation and centerline extraction results at different scales and has better topological continuity than state-of-the-art methods.

An Intestinal Centerline Extraction Algorithm Based on Federated Framework

The intestine is an important organ of the human body, and its internal structure always needs to be observed in clinical applications so as to provide a basis for accurate diagnosis. However, due to the limited intestinal data obtained by a single institution, deep learning cannot effectively train the intestines, and the effect is not satisfied. For this reason, we propose a distributed training method to carry out federated learning to alleviate the situation of patient sample data shortage, not shared and uneven data distribution. And the blockchain is introduced to enhance the interaction between networks, to solve the problem of a single point of failure of the federated learning server. Fully excavate the multiscale features of samples, to construct a fusion enhancement model and intestinal segmentation module for accurate positioning. At the local end, the centerline extraction algorithm is optimized, with the edge as the main and the source as the auxiliary to realize centerline extraction.

Algorithm of Pulmonary Vascular Segment and Centerline Extraction

Because pulmonary vascular lesions are harmful to the human body and difficult to detect, computer-assisted diagnosis of pulmonary blood vessels has become the focus and difficulty of the current research. An algorithm of pulmonary vascular segment and centerline extraction which is consistent with the physician’s diagnosis process is proposed for the first time. We construct the projection of maximum density, restore the vascular space information, and correct random walk algorithm to satisfy automatic and accurate segmentation of blood vessels. Construct a local 3D model to restrain Hessian matrix when extracting centerline. In order to assist the physician to make a correct diagnosis and verify the effectiveness of the algorithm, we proposed a visual expansion model. According to the 420 high-resolution CT data of lung blood vessels labeled by physicians, the accuracy of segmentation algorithm AOM reached 93%, and the processing speed was 0.05 s/frame, which achieved the clinical application standards.

Detection of 3D Arterial Centerline Extraction in Spiral CT Coronary Angiography

This paper presents an in-depth study and analysis of the 3D arterial centerline in spiral CT coronary angiography, and constructs its detection and extraction technique. The first time, the distance transform is used to complete the boundary search of the original figure; the second time, the distance transform is used to calculate the value of the distance transform of all voxels, and according to the value of the distance transform, unnecessary voxels are deleted, to complete the initial contraction of the vascular region and reduce the computational consumption in the next process; then, the nonwitnessed voxels are used to construct the maximum inner joint sphere model and find the skeletal voxels that can reflect the shape of the original figure. Finally, the skeletal lines were optimized on these initially extracted skeletal voxels using a dichotomous-like principle to obtain the final coronary artery centerline. Through the evaluation of the experimental results, the algorithm can extract the coronary centerline more accurately. In this paper, the segmentation method is evaluated on the test set data by two kinds of indexes: one is the index of segmentation result evaluation, including dice coefficient, accuracy, specificity, and sensitivity; the other is the index of clinical diagnosis result evaluation, which is to refine the segmentation result for vessel diameter detection. The results obtained in this paper were compared with the physicians’ labeling results. In terms of network performance, the Dice coefficient obtained in this paper was 0.89, the accuracy was 98.36%, the sensitivity was 93.36%, and the specificity was 98.76%, which reflected certain advantages in comparison with the advanced methods proposed by previous authors. In terms of clinical evaluation indexes, by performing skeleton line extraction and diameter calculation on the results obtained by the segmentation method proposed in this paper, the absolute error obtained after comparing with the diameter of the labeled image was 0.382 and the relative error was 0.112, which indicates that the segmentation method in this paper can recover the vessel contour more accurately. Then, the results of coronary artery centerline extraction with and without fine branch elimination were evaluated, which proved that the coronary artery centerline has higher accuracy after fine branch elimination. The algorithm is also used to extract the centerline of the complete coronary artery tree, and the results prove that the algorithm has better results for the centerline extraction of the complete coronary vascular tree.