In this article, we report a case of varicella in a pregnant woman and her newborn. The woman had moderate varicella infection at the 36th week of pregnancy. She delivered a full-term baby at 38th week, 13 days after first manifestations of varicella. Considering high risk of intrauterine infection, it was decided to prescribe acyclovir at a dose of 10 mg/kg per day divided into 3 portions given every 8 hours to prevent congenital varicella. We installed an umbilical catheter using aseptic technique for intravenous acyclovir infusions. Despite these measures, the newborn developed rash (rare erythematous elements up to 1 mm in diameter) on the chest and right shoulder on day 2. On days 3 and 4, the baby developed maculovesicular rash with a diameter of up to 2–3 mm. On day 5, the newborn demonstrated almost complete resolution of rash. Body temperature was normal. The baby was in good condition and active and was breast-fed. The baby received comprehensive therapy in addition to the causal treatment with acyclovir. This case demonstrates typical course of moderate varicella infection in a pregnant woman and intrauterine varicella in a newborn. The mother became ill shortly before giving birth and, therefore, produced specific antibodies that were transferred through the placenta, which ultimately mitigated varicella infection in the newborn. Key words: varicella, pregnant woman, newborn, acyclovir