Synergistic effects of sinapic acid and ellagic acid ameliorate streptozotocin-induced diabetic nephropathy by inhibiting apoptosis, DNA damage, and structural deterioration in rats

Introduction Diabetic nephropathy (DN), a global problem that threatens human health, is an important reason for chronic kidney disease and kidney failure. In our study, it was aimed to investigate the individual and combined effects of SA and EA in streptozotocin (STZ)-induced rats. Methods The groups are as follows: Control, untreated diabetic, diabetic treated with Sinapic acid (SA), diabetic treated with Ellagic acid (EA), diabetic treated with SA and EA, treated with SA, treated with EA, and treated with SA and EA. Total kidney volume, total glomerulus volume, total filtration space volume, caspase-3, and 8-OHdG immunoreactivity, Malondialdehyde (MDA), Glutathione (GSH), Catalase (CAT), serum urea, and creatinine levels were evaluated by stereological, immunohistochemical, and biochemical methods. Results The findings of the study showed that total kidney volume, total glomerulus volume, total filtration gap volume, caspase-3, and 8-OHdG immunoreactivity, MDA, serum urea, and creatinine levels significantly increased in the untreated diabetic group compared to the control group. Also, severe mesangial and glomerular enlargement, extracellular matrix accumulation, and glomerular and tubular basal membrane thickness were observed in the tubulointerstitial and glomerular of the diabetic rats. However, individual and combined treatments of SA and EA ameliorated these histological changes. Additionally, decreased GSH and CAT in the untreated diabetic group increased by SA and EA treatment. Conclusions The findings suggest that treatment of SA and EA prevent apoptosis and DNA damage and structural changes in STZ-induced DN. However, the combined treatment of SA and EA were more effective than their individual treatments in all parameters except serum urea and creatinine.

Effect of vibration on the efficiency of ultrafiltration

Nowadays, several environmental challenges are present to cope with. One with outstanding importance is the protection of our water supplies, therefore examination of wastewater treatment technology is a priority, especially in the European Union. In this work, the effect of membrane module vibration amplitude on the efficiency of ultrafiltration (UF) was investigated in a vibratory shear enhanced membrane filtration system. Based on the results of model dairy effluent UF and statistical analysis, the maximum vibration level available resulted in the most efficient filtration process, due to the most significant reduction of membrane fouling. From our results it was observed that the permeate fluxes more than doubled, specific energy demand was roughly halved, with almost identical retentions for organic matter, and total filtration resistance was reduced to less than half. Results also showed that setting the optimal operating parameters, an advantageous, efficiency focused, and sustainable wastewater treatment technology can be established.

Determination of Entrance Surface Dose of Digital Radiography for Adults at Public Medical Imaging Centers, Erbil

Introduction: Diagnostic X-ray is one of the ionizing radiations, the level of radiation dose received by the patient during medical examination is essential to prevent cancer risks. The aim of this study is to calculate entrance surface dose (ESD) and effective dose (ED) were estimated during chest, and lumber spine for adult patients in three hospitals in Erbil, using NOMEX MULTIMETER and PCXMC software. Material and Methods: The study was conducted in three public hospitals, in Erbil on (250) adult patients, whose ages between (18-70) years, based on the results study, ESD and ED were calculated for chest (PA, lateral), and lumbar spine (AP, lateral) examinations. NOMEX MULTIMETER (PTW, Freiburg), used in measurement of tube voltage, dose, dose rate, time product current, and total filtration automatically during examination. ED was calculated by using PCXMC software (version 2.5). Results: The results of this work are compared with published international literatures. The mean entrance skin dose for examinations of chest (PA, Lat), and lumber spine (AP, Lat) 1.02, 1.06, 2.61 and 3.92 mGy respectively. ED value was from 0.08, 0.19, 0.32, and 0.33 mSv, for chest (PA, Lat), and lumber spine (AP, Lat), respectively. Conclusion: The ESD, and ED were calculated in this work were found to be agreement with the published reference values for chest, and lumber spine set by international levels. ALARA principle should be considered by radiographer, to reduce absorbed dose of adults’ patient undergoing imaging radiography.

Predictive assessment of the fluid loss properties of thin-layer reservoirs of Vikulovskaya series based on the results of core and well logs

The aim of the work is to predict the filtration capacity of reservoirs based on core and well logs data at the stage of petrophysical study of rocks before the start of active development of the object. All the results were obtained from the data of porometric characteristics of rocks on the example of the vikulovskaya series’s deposits of the Krasnoleninsky arch. The patterns of changes in pore sizes and their contribution to the total filtration depending on the lithophysical type of the rock were established on the core plug. A classification of rocks by pore radii is proposed, and a method for assessing the filtration capacity of reservoirs based on well logs data is developed, with the calculation of the share of each layer in the planned perforation interval

Fouling Analysis and the Recovery of Phytosterols from Orange Juice Using Regenerated Cellulose Ultrafiltration Membranes

This study describes the use of regenerated cellulose (RCA) membranes with molecular weight cut-off (MWCO) values of 10, 30, and 100 kDa, respectively, to separate phytosterols from orange juice for possible nutraceutical production. A desirable membrane separation rejects protein whilst transmitting phytosterols and other low molecular mass compounds such as sugars. The ultrafiltration was performed in a cross-flow membrane system with a total filtration area of 336 cm2. Total phytosterol analysis was carried out by using a Liebermann-Buchard-based method. Protein concentration was quantified by the Bradford method. The effects of three different membranes upon the rejection of total phytosterol content, proteins, sugar, and antioxidant activity were studied. Of the membranes tested, the 10-kDa membrane displayed the highest concentration of phytosterols in the permeate. The 30-kDa and 100-kDa membranes gave comparatively higher phytosterol rejection. The membrane surface roughness and corresponding pure water flux values varied as a function of MWCO such that RCA30 > RCA100 > RCA10. Membranes with rougher surfaces displayed higher fouling than those with smoother surfaces. Hydrophobicity and surface roughness both influenced filtration performance, by controlling the development of the protein-based foulant which modified membrane selectivity.

Effect of soy protein-based flocculant on flocculation and filtration of diatomite and kaolin suspensions

The effect of ethylated soy protein-based bioflocculant (EtSP) as a filter aid reagent was investigated. The efficiency of EtSP as a filter aid was evaluated in terms of the specific cake resistance, α, and was compared with chitosan and polyaluminum chloride (PAC). Diatomite and kaolin were used as model particles. Total filtration resistance, R, decreased with increasing flocculant dosage (wt.%, flocculant/particle) and was almost constant in the range of 1 wt.% or more for both particles. The α value was significantly decreased from 1.01 × 1011 to 9.01 × 1010 m/kg for diatomite and from 5.11 × 1010 to 5.20 × 109 m/kg for kaolin by the addition of EtSP in the case of 1.0 wt.%. The α value for cakes formed by EtSP was much smaller than that formed by chitosan and PAC. In the case of diatomite, in the dose range of 0.5–1.0 wt.%, the α value for cakes formed by EtSP and chitosan was almost the same. However, at the excess dose of 2.0 wt.% over, the α value formed by chitosan abruptly increased. In the case of kaolin, in the dose range of 1.0–2.0 wt.%, the α values of chitosan and PAC were mostly the same, however, these values were larger by ca. nine times than that of EtSP.

A change in oil viscosity during field development influences the Muskat — Leverett model solutions

It has been repeatedly noted in the literature that the physic-chemical properties of oil extracted at different stages of exploitation can vary significantly. We have investigated a modification of the Buckley — Leverett model (BL model) in our previous works to study the influence of oil viscosity change on the solutions of twophase filtration problems. In this model the change in oil viscosity was modeled using the dependence of the viscosity ratio on dynamic water saturation. The solutions to the linear displacement problem at a given total filtration rate were analyzed. This article considers a modification of the two-phase isothermal Muskat — Leverett model (ML model), which takes into account capillary forces. The influence of oil viscosity change in the process of oil production on the structure of the solution is studied numerically a case study of the problem of radial displacement with a given pressure drop.

Advantages of TiO2/carbon nanotube modified photocatalytic membranes in the purification of oil-in-water emulsions

For the effective purification of emulsified oil contaminated waters advanced treatment methods have to be applied, such as membrane filtration, which is able to eliminate macro-, and even nanoscale oil droplets, however, membrane fouling is still a major problem, which prevents economic utilization. Therefore, fouling mitigation is one of the most important aspects in the field of membrane separation developments. In the present study, solely TiO2 and TiO2/carbon nanotubes (CNT) composite modified PVDF membranes were prepared and used to purify oil-in-water emulsions. Achievable fluxes, reversible and irreversible filtration resistances, fouling models, filtration efficiencies and photocatalytic activities were compared in case of different nanomaterial covered and unmodified PVDF membranes. Applying either solely TiO2 or solely CNT coating resulted in the significant reduction of total filtration resistance in both cases, but the combination of the two components (TiO2 with 1 wt% CNT) resulted in by far the highest flux and lowest resistance, meanwhile, the enhanced photocatalytic efficiency of the composite was also achieved. To the best of our knowledge, this study demonstrates the beneficial effects of the combination of TiO2 and CNT nanomaterials for the first time in the field of membrane separation of oil-in-water emulsions.

Using one filter stage of unsaturated/saturated vertical flow filters for nitrogen removal and footprint reduction of constructed wetlands

French vertical flow constructed wetlands (VFCW) treating raw wastewater have been developed successfully over the last 30 years. Nevertheless, the two-stage VFCWs require a total filtration area of 2–2.5 m2/P.E. Therefore, implementing a one-stage system in which treatment performances reach standard requirements is of interest. Biho-Filter® is one of the solutions developed in France by Epur Nature. Biho-Filter® is a vertical flow system with an unsaturated layer at the top and a saturated layer at the bottom. The aim of this study was to assess this new configuration and to optimize its design and operating conditions. The hydraulic functioning and pollutant removal efficiency of three different Biho-Filter® plants commissioned between 2011 and 2012 were studied. Outlet concentrations of the most efficient Biho-Filter® configuration are 70 mg/L, 15 mg/L, 15 mg/L and 25 mg/L for chemical oxygen demand (COD), 5-day biological oxygen demand (BOD5), total suspended solids (TSS) and total Kjeldahl nitrogen (TKN), respectively. Up to 60% of total nitrogen is removed. Nitrification efficiency is mainly influenced by the height of the unsaturated zone and the recirculation rate. The optimum recirculation rate was found to be 100%. Denitrification in the saturated zone works at best with an influent COD/NO3-N ratio at the inflet of this zone larger than 2 and a hydraulic retention time longer than 0.75 days.