acute meningitis
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2022 ◽  
Vol 25 (1) ◽  
pp. 13-21
Author(s):  
Sameh Abdel Monem ◽  
Aya Al Amely ◽  
Ahmed Sharaf ◽  
Naglaa Khalifa ◽  
Omima Taha

2021 ◽  
Vol 12 (3) ◽  
pp. 550-555
Author(s):  
Isam Eldin HA Magid ◽  
Ibrahim Ali Adlan ◽  
Omer Saeed Magzoub ◽  
Omer Ahmed Mohamed Adlan

Bacterial meningitis in infants and children is a serious clinical entity with signs and symptoms that commonly do not allow distinguishing the diagnosis and the causative agents. The only method to determine if meningitis is the cause of these symptoms is a lumbar puncture. Lumbar puncture is the gold standard for the diagnosis and should be done in all suspected cases of meningitis unless contraindicated. Objectives: The purpose of this study is to identify the importance of the microbiological study of cerebrospinal fluid (CSF) in patients suspected to have acute meningitis. Despite the availability of all other investigations and Imaging for diagnosis of meningitis but CSF analysis remains the most available, accurate, and cheaper for diagnosis of meningitis in children. Methodology and result: This is a prospective study. 71 patients were included. All patients were clinically suspected to have acute meningitis. A lumbar puncture for CSF analysis was done for all patients. The data was collected and analysed. CSF culture was done. The culture was negative In 58 patients (81.7%) and positive in 13 patients (18.3%). Streptococcus was found in 3 patients (4.2 %), staphylococcus epidermidis in 2 patients (2.8%), E Coli in 2 patients (2.8%), klebsiella in 2 patients (2.8%), pneumococci in 2 patient (2.8%), salmonella in 1 patient (1,4%) and Bacilli in 1 patient (1.4 %). Recommendation: Lumbar Puncture (LP) remains the easiest, cheapest and accurate investigation for diagnosis of meningitis in children mainly in rural areas in Sudan and other developing countries. It’s mandatory to offer training for doctors and medical staff for doing lumber punctures safely and accurately and to offer well-equipped laboratories for such essential investigations. It’s not only the role of doctors and medical staff but is a governmental obligation as well. This can save a lot of sick children and prevent mortality and morbidity of acute meningitis in children.


2021 ◽  
Vol 66 (2) ◽  
pp. 65
Author(s):  
Devakanthan Balachandran ◽  
Veranja Liyanapathirana ◽  
Nilanthi Dissanayake ◽  
Palitha Harasgama ◽  
Jeewaka Punchihewa

2021 ◽  
Vol 15 (11) ◽  
pp. 554-562
Author(s):  
M. Abdel Monem Sameh ◽  
A. Shora Hassan ◽  
M. Al Amely Aya ◽  
A. Khalifa Naglaa ◽  
L. Sharaf Ahmed

2021 ◽  
Vol 0 (0) ◽  
pp. 13-21
Author(s):  
Sameh Abdel Monem ◽  
aya Al Amely ◽  
naglaa Khalifa ◽  
omima taha ◽  
ahmed sharaf

Author(s):  
Minoosh Shabani ◽  
Shervin Shokouhi ◽  
farnoosh masbough ◽  
Maryam Taleb Shoushtari ◽  
Atousa Hakamifard

We present a case of acute meningitis due to extended-spectrum beta-lactamase-producing E. coli in a patient with immune thrombocytopenic purpura and diabetes mellitus. This challenging entity is uncommon but has a high mortality rate. The exact mechanism for the pathogenesis is not obvious and needs further studies


Viruses ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1438
Author(s):  
Sara Sanbonmatsu-Gámez ◽  
Irene Pedrosa-Corral ◽  
José María Navarro-Marí ◽  
Mercedes Pérez-Ruiz

The sandfly fever Toscana virus (TOSV, genus Phlebovirus, family Phenuiviridae) is endemic in Mediterranean countries. In Spain, phylogenetic studies of TOSV strains demonstrated that a genotype, different from the Italian, was circulating. This update reports 107 cases of TOSV neurological infection detected in Andalusia from 1988 to 2020, by viral culture, serology and/or RT-PCR. Most cases were located in Granada province, a hyperendemic region. TOSV neurological infection may be underdiagnosed since few laboratories include this virus in their portfolio. This work presents a reliable automated method, validated for the detection of the main viruses involved in acute meningitis and encephalitis, including the arboviruses TOSV and West Nile virus. This assay solves the need for multiple molecular platforms for different viruses and thus, improves the time to results for these syndromes, which require a rapid and efficient diagnostic approach.


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