Supine sleep patterns as a part of phenotyping patients with sleep apnea—a pilot study

Purpose Polysomnography (PSG) is considered the best objective study to diagnose and quantify sleep disorders. However, PSG involves multiple electrodes and is usually performed in a sleep laboratory that in itself may change the physiology of sleep. One of the parameters that can change during PSG is the sleep position, leading to more supine sleep. The aim of this study was to quantify the amount of supine sleep during PSG and compare it to consecutive nights of a home sleep apnea test (HSAT) in the same patients. Methods This prospective study evaluated 22 consecutive patients undergoing PSG followed by HSAT. Sleep position was analyzed during PSG and subsequently on 2 to 6 nights (mean 3.7 nights) at home, and the amount of supine sleep was recorded during each night. Results Of 22 patients, there were 12 men (55%). The median age was 60.0 years for women and 45.5 years for men. Median proportion of supine sleep during PSG and HSAT was 61% and 26% (p < 0.001), respectively. Four “phenotypes” were identified according to their sleep position during PSG and HSAT, with 5 patients sleeping mainly supine during all nights, 7 patients sleeping mainly non-supine during all nights, 3 patients sleeping in different positions during each night, and 7 patients sleeping supine during PSG but non-supine at home, during HSAT. Conclusions There is a higher proportion of supine sleep during PSG compared to home sleep. We identified a subgroup of patients who slept mainly supine during PSG and mainly non-supine during HSAT. PSG may overestimate OSA severity in a specific phenotype of patients.

Financial Technology Regulation in Malaysia and Indonesia: A Comparative Study

Introduction to The Problem: The era of innovation in information technology has emerged to ease daily commercial transactions. The innovation in financial technology has created numerous new business model to cater the customers’ need. This development needs a regulation and supervision to avoid chaos in the financial system. Particularly in Indonesia and Malaysia, which both countries were recorded by CCAF to be among the top countries in the ASEAN region by the number of fintech firms.Purpose/Objective Study: This study is aimed to analyze the financial technology regulation and supervision in Indonesia and Malaysia.Design/Methodology/Approach: The comparative study is conducted to compare the regulatory environment related to Digital payment, Equity Crowdfunding, P2P lending, Crypto Asset, Consumer protection, cybersecurity law and Islamic fintech in both countriesFindings: The study found that compared to Malaysia, Indonesia has lack of jurisdiction that protecting the customer from the cyber-attack which highly threatening the fintech industry. Both countries also treat ICO differently. Malaysia treats it under RMO guidelines, while Indonesia banned it as the method of payment but still allows the trading of ICO as a commodity under Commodity Futures Regulatory Agency.

Married Dostoevsky? The History of Relations between V.V. Rozanov and A.P. Suslova

The article examines in detail the history of the relationship between A.P. Suslova and V.V. Rozanov in connection with the notion existing in the historical and literary science that Rozanovs marriage to Suslova was based on his deep interest in the work of F.M. Dostoevsky and his desire in such an unusual way to penetrate deeper into the secrets of the life and work of the author of The Idiot and The Brothers Karamazov. However, an appeal to various documentary evidence shows that Rozanovs marriage motives came from the warehouse of his nature and constituted a complex of rather complex reasons, among which the human, and not literary, research principle still dominates. The desire for a benevolently objective study of the life history of A.P. Suslova makes it possible to clarify at the modern scientific level the important facts of the biography of F.M. Dostoevsky and V.V. Rozanov, to free them from the stratifications of legends and myths.

A STUDY OF CORRELATION OF PRAGMATIC RISK SCORE WITH MORTALITY IN PATIENTS ADMITTED TO RLJH AND RC ICU WITH CORONAVIRUS DISEASE 2019 (COVID-19)

Background : In many people the disease is mild and self-limiting, but in a considerable portion of patients the disease is severe and fatal. Determining which patients are at high risk of severe illness or mortality is an essential part of understanding this illness Aims and Objective : Study of correlation of prognostic risk score with mortality in patients admitted to RLJH and RC ICU with coronavirus disease 2019 (COVID-19) . Methodology : This was a Retrospective observational study in the patients tested RT-PCR positive for COVID 19 and admitted at SRI DEVARAJ URS MEDICAL COLLEGE Tamaka, Kolar during the two month duration i.e. June 2021 to July 2021 in the 50 patients .The statistical analysis was done by Graph pad prism 6 version from that we have calculated correlation co-efcient and Survival graph Result : In our study we have seen that The majority of the patients were in the age group of 61-70 were 28% , followed by 51-60 were 24%, 71-80 were 22%, 41-50 were 14% , 30-40 & >80 were 6%. The majority of the patients were Male i.e. 68% and Female were 32%. There was strong correlation between Prognostic score and mortality of the patients which was statistically highly signicant i.e. Spearman r= 0.8450, P value (two-tailed) was < 0.0001*** . survival rate for the Score 0, 2 was almost 100% and as the score increases i.e. 3,4,5,6 there survival percentage also decrease approximately to 25 %, 5% and 0%,0% respectively. Conclusion :It can be concluded from our study that there was signicantly higher coreltaion between the Prognostic score and mortality of the patients hence this score could be reliable tool for the assessment of the severe patients and prompt and aggressive treatment for the better outcome

Dermatovenerological service of Ukraine in the context of ongoing reform

The problems of preserving the dermatovenerological health of the population are extremely relevant for Ukraine, where diseases of the skin and subcutaneous tissue occupy the 5th place in the structure of morbidity. Objective — study of the structure of the dermatovenerological service in the context of reforming the healthcare system at this stage (end of 2021) and its characteristics. Materials and methods. The results of the analysis of the state of resources of medical institutions of communal ownership of dermatovenerological profile in Ukraine are presented. Results and discussion. Today, in Ukraine, the number of hospital beds for 24-hour hospitals for adults is 188 in the regions (Zaporizhzhia, Rivne, Kharkiv, Cherkasy) and 220 beds in Kyiv city, which is extremely insufficient. There are 24 beds for the pediatric patients in the regions (Luhansk, Rivne, Cherkasy) and in the city of Kyiv — 60. The number of day hospital beds for adults has significantly decreased — to 248 in the regions (Dnipropetrovs’k, Zaporizhzhia, Kyiv, Lviv, Poltava, Kherson, Cherkasy, Chernivtsi and Kramatorsk city), for pediatric patients — 61 (Dnipropetrovs’k, Kropyvnytskyi, Mykolaiv, Poltava regions). In 2021, 11 dermatovenerologic dispensaries were liquidated. Instead of them, dermatovenero­logic centers and subdivisions subordinate to regional hospitals were formed. Thus, there is an unfavorable restructuring of the bed fund of institutions providing dermatovenerological care. Conclusions. A decrease in the number of state and municipal institutions providing free dermatovenerological care will lead to the worsening of the epidemic situation, the spread of sexually transmitted infections and reduction of the availability of specialized dermatovenerological care for the population in a difficult economic and social situation.

Relevant issues of the technosphere safety in the process of using construction equipment

Objective: Study of the technosphere safety issues relating to the use of construction equipment. Analysis of regulatory framework in this field. Methods: Study of the main causes of accidents in construction has been carried out. Results: Ways to minimize risks and examples of accidents that threaten the technosphere safety when using construction equipment are given. Practical im-portance: It has been established that it is necessary to reduce the risk of accidents due to human error. This can be done in a variety of ways. For example, in order to avoid accumulated fatigue, one should provide a rational work and rest pattern, carry out professional selection when hiring, conduct tests, in particular for reality awareness, for personal qualities (level of responsibility, punc-tuality, etc.), and conduct professional retraining or qualification upgrade. Regular employee health checks are necessary. It is important to learn how to predict the possible consequences to pro-vide security of the decisions made.

About the development of bone tissue in goiter

In May 1921, a patient with a significant goiter came to the Faculty Surgical Clinic of Kazan University for an outpatient appointment with a request for an operation. The patient was admitted to the clinic, and in view of the rare and extremely interesting features that the goiter presented in her during its objective study, this case was kindly provided to me by the then temporarily in charge of the clinic, prof. VN Larin for research and description.

Improvement of personnel policy in the state civil service in the office of the State Duma of the Federal Assembly of the Russian Federation

The problems caused by the need to improve the quality of the personnel of the state civil service are analysed. The article is prepared on the basis of a study in the form of a sociological survey conducted in the Apparatus of the State Duma of the Federal Assembly of the Russian Federation with the aim of the most detailed and objective study of the effectiveness of personnel policy in the office of legislative bodies of state power, in particular in the Apparatus of the State Duma, and subsequent development of recommendations for improving personnel policy. The main emphasis is made on the development of personnel policy based on modern mechanisms for the formation of personnel. A number of recommendations and measures are formulated to perfect the motivation and improve the professional level of state civil servants of the State Duma Apparatus.

Creativity of teachers-choreographers of the Terebovlyan Cultural Education School of Anatolii and Oleksandra Polishchuk

The purpose of the article is to identify the main aspects of the work of choreographers of the Terebovlya Cultural Education School Anatolii and Oleksandra Polishchuk. Methodology. The use of a set of general and special methods, such as analysis and synthesis, culturological approach, consideration of events in chronological order, art analysis to identify stylistic features of choreographic productions by A. Polishchuk, etc., contributed to the objective study. Scientific novelty. For the first time, a special study is devoted to the works of Anatolii and Oleksandra Polishchuk, their role in the development of the choreographic culture of the Ternopil region is clarified, stylistic features of A. Polishchuk’s choreographic performances are revealed. Conclusions. The powerful artistic impulse received by Anatolii and Oleksandra Polishchuk, future teachers of the Terebovlya Cultural Education School, at the O. E. Korniychuk Kyiv State Institute of Culture made it possible to reach the highest levels of artistic and pedagogical skill in the Ternopil region. They resumed the work of the dance ensemble at the school, created a folk dance ensemble "Chervona kalyna" in Ternopil. A. Polishchuk's choreography combined artistic rethinking of Nadzbruchany choreographic folklore, interpretation of dances that became symbols of Ukrainian folk choreography ("Kozachok", "Hopak", etc.) with author's choreographic compositions, the figurative structure of which is closely related to the rich folk culture, in particular, the symbolism of household items and psychoemotional characteristics as a sign of ethnic mentality ("Chervona kalyna", "Loburyaki").