UV SPECTROPHOTOMETRY IN THE ANALYSIS OF A COMBINED MEDICINAL PRODUCT BASED ON DRY LICORICE ROOT EXTRACT

Работа посвящена разработке методики количественного определения глицирризина и аскорбиновой кислоты при их совместном присутствии в комбинированном лекарственном препарате в виде саше методом УФ-спектрофотометрии. This paper represents a developed technique for the quantitative determination of a new medicinal composition based on dry licorice extract and ascorbic acid for the prevention and treatment of immunode ciency in viral infections by UV spectrophotometry

PROSPECTS FOR THE CREATION OF MEDICINES BASED ON A NATURAL ADAPTOGEN IN THE COMPLEX THERAPY OF VIRAL INFECTIONS

В статье описано современное состояние распространения, переработки и использования солодки в Казахстане. Представлены литературные данные использования компонентов корня солодки в создании лекарственных средств для профилактики и лечения иммунодефицитного состояния при вирусных инфекциях. Обобщены литературные данные о комбинированных препаратах, содержащих экстракт корня солодки, глицирризиновую кислоту. The article describes the current state of distribution, processing and use of licorice in Kazakhstan. The literature data on the use of licorice root components in the creation of medicines for the prevention and treatment of immunodeficiency in viral infections are presented. The literature data on combined preparations containing licorice root extract and glycyrrhizic acid are summarized.

Effect of Spraying With Benzyl Adenine and Licorice Root Extract on Some Vegetative Growth Characteristics and Chemical Content of Strawberry (Fragaria Ananassa Duch) CV. Rubygem

This study was conducted inside the plastic house of the Agricultural Research and Experiment Station of the Agriculture College - University of Kirkuk/Iraq, during the growing season 2020/2021. To study the effect of spraying the growth regulator of benzyl adenine in three concentrations (0, 30, 60) mg.L−1 and licorice root extract in three concentrations (0, 3000, 6000) mg.L−1 on some growth characteristics and chemical content of strawberry plants of Rubygem type. The obtained results were summarized that spraying with a concentration of 60 mg.L−1 of the growth regulator benzyl adenine BA led to a significant superiority in most growth characteristics and chemical content of strawberry plants (leaf area, leaves number, leaves area, dry matter in plant, leaf content of chlorophyll and nitrogen total) where reached (95.81 cm2, 15.78 leaf. plant−1, 1513.93 cm2, 38.68 %, 28.66 %, 3.24 %) respectively. While spraying with concentrations (30 and 60 mg.L−1)of benzyl adenine was significantly superior to the control treatment in the phosphorous and carbohydrates content of leaves. Spraying with a concentration of 6000 mg.L−1 of licorice extract significantly increased in most of the study traits (dry matter in plant, leaf content of chlorophyll, nitrogen, phosphorous and carbohydrates total) where reached (39.06 %, 25.69 mg.g−1, 3.09 %, 0.334 %, 3.38 %) respectively. Spraying with a concentration of 3000 mg.L−1 of licorice was significantly superior in the characteristics of leaf area and Leaves area, which reached (85.08, 1303.18) cm2 respectively.

Licorice Root Ethanol Extract Induces Cell Proliferation in Human Osteoblast Cells

Licorice, also known as the root of Glycyrrhiza glabra, has been used for many years in traditional medicine to treat various diseases. Licorice root has remarkable pharmacological properties and these biological effects are predominantly attributed to its content of polyphenols and flavonoids. The aim of this study was to determine the proliferative effect of licorice root extract on human osteoblast cells. The study groups were exposed to various concentrations of licorice root extract on 31.25, 62.5, 250, 500, 1000 μg/mL for 24, and 48 h. The proliferative effect of the extract on human osteoblast cells was assessed using the MTT assay. After 24 and 48 h, cell proliferation of groups treated were increased statistically significant compared to the control cells, and also all concentrations showing no cytotoxic effects on osteoblast cells. Phytomedical applications of licorice root may represent a promising approach in the treatment of periodontal regeneration and osteoporosis.