In quantum mechanics, entangled states are not exotic or rare. Rather, entanglement is the norm and so the metaphysical consequences of entanglement are a central issue for anyone wishing to provide an ontological interpretation of the various formulations of quantum mechanics. This chapter presents the argument for wave function realism from quantum entanglement, which says that wave function realism is necessary if one wants an ontological interpretation that does not conflate distinct quantum states. It explains quantum entanglement and how postulating a wave function in higher dimensions can help to metaphysically ground the phenomenon. The chapter ultimately concludes that the argument from quantum entanglement fails as there are several rival positions that can also explain quantum entanglement and recover the distinctions between different entangled states. These include the primitive ontology approach, various other holisms, ontic structural realism, spacetime state realism, and the multi-field approach.