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scholarly journals Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

2022 ◽  
Author(s):  
Valeria Napolitano ◽  
Agnieszka Dabrowska ◽  
Kenji Schorpp ◽  
André Mourão ◽  
Emilia Barreto-Duran ◽  
...  

scholarly journals Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality

2022 ◽  
Author(s):  
Michael A. Lobritz ◽  
Ian W. Andrews ◽  
Dana Braff ◽  
Caroline B.M. Porter ◽  
Arnaud Gutierrez ◽  
...  
Keyword(s):  
Energy Demand ◽  
Lactam Antibiotic

An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance

2022 ◽  
Author(s):  
Maya Matsushita ◽  
Motoharu Awazawa ◽  
Naoki Kobayashi ◽  
Yoshiko Matsumoto Ikushima ◽  
Kotaro Soeda ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Hepatic Steatosis ◽  
Antisense Transcript

Chemoselective restoration of para-azido-phenylalanine at multiple sites in proteins

2021 ◽  
Author(s):  
Pol Arranz-Gibert ◽  
Koen Vanderschuren ◽  
Adrian Haimovich ◽  
Anushka Halder ◽  
Kallol Gupta ◽  
...  

3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis

2021 ◽  
Author(s):  
Chenwen Shao ◽  
Yani Liu ◽  
Zhangpeng Chen ◽  
Yajuan Qin ◽  
Xueao Wang ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Iron Homeostasis ◽  
Two Photon

Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production: A paradox resolved

2021 ◽  
Vol 28 (12) ◽  
pp. 1665-1668
Author(s):  
Christopher Hine ◽  
Derek A. Wainwright ◽  
Justin D. Lathia
Keyword(s):  
Dna Damage ◽  
Damage Detection ◽  
Cellular Autophagy ◽  
H2s Production

Identification of small molecules that strongly inhibit bacterial quorum sensing using a high-throughput lipid vesicle lysis assay

2021 ◽  
Author(s):  
Thomas J. Polaske ◽  
Curran G. Gahan ◽  
Kayleigh E. Nyffeler ◽  
David M. Lynn ◽  
Helen E. Blackwell
Keyword(s):  
Quorum Sensing ◽  
Small Molecules ◽  
High Throughput ◽  
Lipid Vesicle ◽  
Bacterial Quorum Sensing ◽  
Bacterial Quorum

scholarly journals Potent macrocycle inhibitors of the human SAGA deubiquitinating module

2021 ◽  
Author(s):  
Michael Morgan ◽  
Tatsuya Ikenoue ◽  
Hiroaki Suga ◽  
Cynthia Wolberger

Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds

2021 ◽  
Author(s):  
Mohammad Akbarzadeh ◽  
Ilka Deipenwisch ◽  
Beate Schoelermann ◽  
Axel Pahl ◽  
Sonja Sievers ◽  
...  

scholarly journals Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment

2021 ◽  
Vol 28 (12) ◽  
pp. 1807
Author(s):  
Victoria Sanchez-Martin ◽  
David A. Schneider ◽  
Matilde Ortiz-Gonzalez ◽  
Ana Soriano-Lerma ◽  
Angel Linde-Rodriguez ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Rna Polymerase ◽  
Cancer Treatment ◽  
Rna Polymerase I ◽  
Polymerase I ◽  
Naphthalene Diimides ◽  
Colorectal Cancer Treatment
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