Fractional derivatives have been proven to showcase a spectrum of solutions that is useful in the fields of engineering, medical, and manufacturing sciences. Studies on the application of fractional derivatives on fluid flow are relatively new, especially in analytical studies. Thus, geometrical representations for fractional derivatives in the mechanics of fluid flows are yet to be discovered. Nonetheless, theoretical studies will be useful in facilitating future experimental studies. Therefore, the aim of this study is to showcase an analytical solution on the impact of the Caputo-Fabrizio fractional derivative for a magnethohydrodynamic (MHD) Casson fluid flow with thermal radiation and chemical reaction. Analytical solutions are obtained via Laplace transform through compound functions. The obtained solutions are first verified, then analysed. It is observed from the study that variations in the fractional derivative parameter, α, exhibits a transitional behaviour of fluid between unsteady state and steady state. Numerical analyses on skin friction, Nusselt number, and Sherwood number were also analysed. Behaviour of these three properties were in agreement of that from past literature.