scholarly journals Correction to: Fertility Intentions Within a 3-Year Time Frame: a Comparison Between Migrant and Native Italian Women

Author(s):  
Eleonora Mussino ◽  
Giuseppe Gabrielli ◽  
Livia Elisa Ortensi ◽  
Salvatore Strozza

A Correction to this paper has been published: 10.1007/s12134-020-00800-2

Author(s):  
Marco Novelli ◽  
Alberto Cazzola ◽  
Aurora Angeli ◽  
Lucia Pasquini

AbstractThis study analyses the socio-economic determinants of the short-term fertility plans of Italian women and men living as couples, before and shortly after the onset of the 2007/2008 Great Recession, which may have affected their reproductive plans through a climate of rising economic uncertainty. Using multilevel models, we investigate how fertility intentions are related to the individual characteristics of the respondents and their partners as well as to changes in the economic context. The findings confirm that the Great Recession modified the determinants of short-term fertility intentions differently for women and men. Among the most relevant issues, we outline the importance of couples’ working conditions and the contextual labour market indicators.


Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Silvia Molino ◽  
Andrea Pisarevsky ◽  
Fabiana Lopez Mingorance ◽  
Patricia Vega ◽  
Juan Pablo Stefanolo ◽  
...  

Abstract Objectives This research aims to study the efficacy of tannins co-supplementation on disease duration, severity and clinical symptoms, microbiota composition and inflammatory mediators in SARS-CoV2 patients. Trial design This is a prospective, double-blind, randomized, placebo-controlled, parallel-group trial to evaluate the efficacy of the administration of the dietary supplement ARBOX, a molecular blend of quebracho and chestnut tannins extract and Vit B12, in patients affected by COVID-19. Participants 18 years of age or older, admitted to Hospital de Clinicas Jose de San Martin, Buenos Aires University (Argentina), meeting the definition of "COVID-19 confirmed case" (https://www.argentina.gob.ar/salud/coronavirus-COVID-19/definicion-de-caso). Inclusion Criteria Participants are eligible to be included in the study if the following criteria apply: Any gender ≥18 years old Informed consent for participation in the study Virological diagnosis of SARS-CoV-2 infection (real-time PCR) Exclusion Criteria Participants are excluded from the study if any of the following criteria apply: Pregnant and lactating patients Patients who cannot take oral therapy (with severe cognitive decline, assisted ventilation, or impaired consciousness) Hypersensitivity to polyphenols Patients already in ICU or requiring mechanical ventilation Patients already enrolled in other clinical trials Decline of consent Intervention and comparator Experimental: TREATED ARM Participants will receive a supply of 28 -- 390 mg ARBOX capsules for 14 days. Patients will be supplemented with 2 capsules of ARBOX per day. Placebo Comparator: CONTROL ARM Participants will receive placebo supply for 14 days. The placebo will be administered with the identical dose as described for the test product. All trial participants will receive standard therapy, which includes: Antipyretics or Lopinavir / Ritonavir, Azithromycin and Hydroxychloroquine, as appropriate (treatment currently recommended by the department of Infectious Diseases of the Hospital de Clínicas that could undergo to modifications). In addition, if necessary: supplemental O2, non-invasive ventilation, antibiotic therapy. Main outcomes Primary Outcome Measures: Time to hospital discharge, defined as the time from first dose of ARBOX to hospital discharge [ Time Frame: Throughout the Study (Day 0 to Day 28) ] Secondary Outcome Measures: 28-day all-cause mortality [ Time Frame: Throughout the Study (Day 0 to Day 28) ]-proportion Invasive ventilation on day 28 [ Time Frame: Throughout the Study (Day 0 to Day 28) ]-proportion Level of inflammation parameters and cytokines [ Time Frame: day 1-14 ] -mean difference Difference in fecal intestinal microbiota composition and intestinal permeability [ Time Frame: day 1-14 ] Negativization of COVID-PCR at day 14 [ Time Frame: day 14 ]-proportion Randomization Potential study participants were screened for eligibility 24 hours prior to study randomization. Patients were randomly assigned via computer-generated random numbering (1:1) to receive standard treatment coupled with tannin or standard treatment plus placebo (control group). Blinding (masking) Study personnel and participants are blinded to the treatment allocation, as both ARBOX and placebo were packed in identical containers. Thus, all the used capsules had identical appearance. Numbers to be randomized (sample size) Considering an alpha error of 5%, a power of 80% a sample size of 70 patients per branch was estimated. 140 patients in total. Trial Status The protocol version is number V2, dated May 23, 2020. The first patient, first visit was on June 12, 2020; the recruitment end date was October 6, 2020. The protocol was not submitted earlier because the enrollment of some patients took place after the closure of the recruitment on the clinicaltrials platform. In fact, due to the epidemiological conditions, due to the decrease of the cases in Argentina during the summer period, the recruitment stopped t before reaching the number of 140 patients (as indicated in the webpage). However, since there was a new increase in cases, the enrolment was resumed in order to reach the number of patients initially planned in the protocol. The final participant was recruited on February 14, 2021. Trial registration ClinicalTrials.gov, number: NCT04403646, registered on May 27th, 2020. Full protocol The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.


2013 ◽  
Vol 32 (3) ◽  
pp. 373-413 ◽  
Author(s):  
Francesca Fiori ◽  
Francesca Rinesi ◽  
Antonella Pinnelli ◽  
Sabrina Prati

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e023833 ◽  
Author(s):  
Erwan L’her ◽  
Samir Jaber ◽  
Daniel Verzilli ◽  
Christophe Jacob ◽  
Brigitte Huiban ◽  
...  

IntroductionHypoxemia and hyperoxia may occur after surgery with potential related complications. The FreeO2PostOp trial is a prospective, multicentre, randomised controlled trial that evaluates the clinical impact of automated O2administration versus conventional O2therapy after major abdominal or thoracic surgeries. The study is powered to demonstrate benefits of automated oxygen titration and weaning in term of oxygenation, which is an important surrogate for complications after such interventions.Methods and analysisAfter extubation, patients are randomly assigned to theStandard(manual O2administration) orFreeO2group (automated closed-loop O2administration). Stratification is performed for the study centre and a medical history of chronic obstructive pulmonary disease (COPD). Primary outcome is the percentage of time spent in the target zone of oxygen saturation, during a 3-day time frame. In both groups, patients will benefit from continuous oximetry recordings. The target zone of oxygen saturation is SpO2=88%–92% for patients with COPD and 92%–96% for patients without COPD. Secondary outcomes are the nursing workload assessed by the number of manual O2flow adjustments, the time spent with severe desaturation (SpO2<85%) and hyperoxia area (SpO2>98%), the time spent in a hyperoxia area (SpO2>98%), the VO2, the duration of oxygen administration during hospitalisation, the frequency of use of mechanical ventilation (invasive or non-invasive), the duration of the postrecovery room stay, the hospitalisation length of stay and the survival rate.Ethics and disseminationThe FreeO2PostOp study is conducted in accordance with the declaration of Helsinki and was registered on 11 September 2015 (http://www.clinicaltrials.gov). First patient inclusion was performed on 14 January 2016. The results of the study will be presented at academic conferences and submitted to peer-reviewed journals.Trial registration numberNCT02546830.


2015 ◽  
Vol 20 (3) ◽  
Keyword(s):  

Abstract Download the CE Questions PDF from the toolbar, above. Use the questions to guide your Perspectives reading. When you're ready, purchase the activity from the ASHA Store and follow the instructions to take the exam in ASHA's Learning Center. Available until August 13, 2018.


2012 ◽  
Vol 22 (2) ◽  
Author(s):  
Kathryn Taylor ◽  
Emily White ◽  
Rachael Kaplan ◽  
Colleen M. O'Rourke
Keyword(s):  

Sorry, this activity is no longer available for CEUs. Visit the SIG 11 page on the ASHA Store to see available CE activities. Use the CE questions PDF here as study questions to guide your Perspectives reading.


Keyword(s):  

Sorry, this activity is no longer available for CEUs. Visit the SIG 14 page on the ASHA Store to see available CE activities. Use the CE questions PDF here as study questions to guide your Perspectives reading.


Author(s):  
Celeste Domsch
Keyword(s):  

Sorry, this activity is no longer available for CEUs. Visit the SIG 17 page on the ASHA Store to see available CE activities. Use the CE questions PDF here as study questions to guide your Perspectives reading.


2012 ◽  
Vol 21 (4) ◽  
pp. 1-6 ◽  
Author(s):  
Cathy Binger ◽  
Jennifer Kent-Walsh
Keyword(s):  

Sorry, this activity is no longer available for CEUs. Visit the SIG 12 page on the ASHA Store to see available CE activities. Use the CE questions PDF here as study questions to guide your Perspectives reading.


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