Comprehensive literature review of the sources of infection and transmission routes of Coxiella burnetii, with particular regard to the criteria of “evidence-based medicine”

Author(s):  
Lisa Marie Koehler ◽  
Bärbel Kloppert ◽  
Hans-Peter Hamann ◽  
Amr El-Sayed ◽  
Michael Zschöck
Author(s):  
Ping Li ◽  
Lin Wu

This study sought to find out whether and how health sciences librarians’ roles have been changing to support the evidence-based medicine (EBM) practice. Both content analysis of job advertisements and literature review were employed. Results revealed that there exist some disconnects between what are expected of health sciences librarians in…Cette étude visait à déterminer si le rôle des bibliothécaires du domaine des sciences de la santé a évolué et de quelle manière ce rôle est en mesure de subvenir aux besoins de la médecine fondée sur les preuves (MFP). L’analyse de contenu des offres d’emploi et la revue de la littérature a été employée. Les résultats ont révélé qu’il existe un fossé entre ce que l’on attend des bibliothécaires des sciences de la santé en… 


Relevance. In today's world, the first cause of death is pathology of the cardiovascular system. Vascular disease is influenced by many factors: lack of sleep, physical inertia, poorly balanced diet, obesity, heart disease. The fast pace of life forces a person to be in permanent stress, so as not to miss anything and have time for all the goals. This is why there is a demand for excipients and substances that could improve the peak of human cognitive abilities, maintain psychological stability. Today, the pharmaceutical market offers drugs that, according to pharmaceutical marketers, have solutions to the problems outlined above. These substances are classified to group of nootropic drugs (racetams). Objective. Review of high quality research on the effectiveness of nootropic drugs. Materials and methods. The literature review was performed using such scientometric databases as: PubMed, Cochrane Library, Scopus, BMJ Evidence-Based Medicine, Ingecta, Web of Science, UpToDate. The review included studies of randomized trials, placebo-controlled randomized trials, meta-analyzes, and systematic reviews. Data meet criteria A and B of evidence-based medicine. In the absence of high quality studies, studies with a lower level of evidence were selected. The search was made by topics: improving of cognitive functions, improving ability to work, improving sleep, improving mood, treatment of mental and psychiatric pathologies (Alzheimer's disease, dementia with various etiologies, depression), application in pediatrics. Results. The literature review included more than 40 high quality studies, but no conclusive evidence was found on the effectiveness of any drug. Conclusions. Data on the undeniable efficacy in relation to the cognitive functions of any of these nootropic drugs were not found in any study. In the treatment of Alzheimer's disease, some (Cerebrolysin, Nicergoline) drugs show controversial results of efficacy and safety. They require continued clinical research and they need to be approved by the FDA.


2015 ◽  
Vol 129 (7) ◽  
pp. 622-626 ◽  
Author(s):  
N C Seymour

AbstractObjective:To review the literature on the outcomes of ENT operations in order to assess whether ENT operations are effective.Methods:The value of evidence-based medicine in relation to ENT was appraised, as was the perception of effectiveness. Literature on common ENT operations, including grommet insertion, tonsillectomy and adenoidectomy, and correction of the nasal septum, was evaluated.Results and conclusion:When evaluating the effectiveness of ENT operations, the patient's overall condition and improvements after surgery should be measured. Objective and subjective factors should both be considered as good evidence, especially with the increasing role that evidence-based medicine plays in decisions of whether to operate. The literature review provides evidence that ENT operations are effective.


2016 ◽  
Vol 16 (6) ◽  
pp. e35
Author(s):  
Nathan R. Stehouwer ◽  
Diana Yan ◽  
Elise Bream ◽  
Gina Posluszny ◽  
Ross Myers ◽  
...  

2014 ◽  
Vol 29 (1_suppl) ◽  
pp. 188-192 ◽  
Author(s):  
FS Catarinella ◽  
I Stavast ◽  
CHA Wittens

Introduction: Evidence based medicine is not the ideal way to assess and evaluate treatment success, failure and outcomes. Modern technology makes it possible to register a multitude of information. Advances in the venous field are fast and require a more efficient way to allow selection based on outcomes and quality. Registries are theoretically contain the data needed to investigate venous treatments and instruments. Materials and methods: A literature review was performed and twenty-five articles were selected for review. Results: Current registries fail to perform as needed and do not deliver the needed information. Separate frameworks and applications are available, but up until now no centralized and combined effort has been made to create a true all encompassing European venous registry. Conclusions: A European venous registry containing standardized variables regarding all aspects of venous disease is needed to truly investigate and improve our care. An intuitive and integrated EHR application can facilitate the gathering of data needed to create such a registry. A number of rules apply though.


Author(s):  
Jefferson Walter Daniel ◽  
José Carlos Esteves Veiga

Introduction: A measure of an epidemiological event occurrence contributes in institutional health planning, resource allocation, sickness trend prediction and a surgical divisions operating profile. Objective: Census in prevalence of spinal epidural metastases among spinal and spinal tissue neoplasms in the neurosurgical context is the encountered epidemiological literature gap and the proposed reason for this research. Methods: A surgically treated spinal neoplasms patient descriptive cross-sectional update census was performed between February 1997 and January 2018 in a single neurosurgical division. In addition, using the systematic research method for literature review, authors selected comparative descriptive studies in patients submitted to surgical procedures for spinal epidural metastases, epidural primary and intradural neoplasms. The methodological quality analysis was in accordance to the Oxford Centre for Evidence-Based Medicine. Results: The primary outcome obtained in the cross-sectional descriptive update study indicated that 128 neurologically symptomatic patients were submitted to surgical procedures for spinal metastases and represented 0.84% of the 15,061-neurosurgical procedures. As for the secondary outcome, literature review identified 3 comparative studies: 1 cross-sectional and 2 case-series. In a cohort of 866 (100%) patients submitted to surgical treatment, 191 (22.05%) patients were operated for spinal metastases, 83 (9.59%) for epidural primary neoplasms and 592 (68.36%) for intradural neoplasms. Clinical appraisals identified Grade C recommendation for the 3 included items. Conclusion: Spinal intradural neoplasms are prevalent when compared to spinal metastases and spinal metastases are the most common histologic tumor type group in patients submitted to surgical treatment.Keywords: Neoplasm metastasis; Epidemiology; Spine; Surgical procedures, operativeRESUMOIntrodução: À medida que ocorra um evento epidemiológico, o mesmo contribuirá no planejamento do atendimento à saúde numa Instituição no tocante à alocação de recursos, à previsão de tendências de doenças e a caracterização do perfil de procedimentos cirúrgicos de um departamento de cirurgia. Objetivo: Estabelecer censo na prevalência de metástases epidurais dentre as neoplasias da coluna vertebral e do tecido nervoso nela contido. No contexto neurocirúrgico é a lacuna epidemiológica encontrada na literatura e o motivo proposto desta pesquisa. Métodos: Foi realizado um censo de atualização descritiva transversal de pacientes submetidos a cirurgias espinhais no período entre fevereiro de 1997 e janeiro de 2018 em uma única divisão neurocirúrgica. Ademais, utilizando o método de pesquisa sistemática para revisão da literatura, os autores selecionaram estudos descritivos comparativos de pacientes com diagnóstico de neoplasias epidurais secundárias, epidurais primárias e intradurais submetidos a procedimentos cirúrgicos em coluna vertebral. A análise metodológica da qualidade dos estudos foi realizada de acordo com o Oxford Center for Evidence-Based Medicine. Resultados: O desfecho primário obtido no estudo de atualização descritiva transversal indicou que 128 pacientes neurologicamente sintomáticos foram submetidos a procedimentos cirúrgicos em metástases espinhais e representaram 0,84% do total de 15.061 procedimentos neurocirúrgicos em geral. Quanto ao desfecho secundário, a revisão de literatura identificou 3 estudos comparativos: 1 transversal e 2 séries de casos. Em uma coorte de 866 (100%) pacientes submetidos a tratamento cirúrgico, 191 (22,05%) foram operados para metástases espinhais, 83 (9,59%) para neoplasias primárias epidurais e 592 (68,36%) para neoplasias intradurais. A análise metodológica da qualidade dos estudos identificou recomendação Grau C para os 3 itens incluídos. Conclusão: As neoplasias intradurais da coluna vertebral são prevalentes quando  comparadas às metástases espinhais e estas últimas são o tipo histológico  mais comum em pacientes submetidos a tratamento cirúrgico em coluna vertebral.Descritores: metástase neoplásicas, Epidemiologia, Coluna vertebral, Procedimentos cirúrgicos operatórios


Author(s):  
Andrea L. Nicol ◽  
Usman Latif

This chapter reviews concepts underlying critical analysis of literature and evidence-based medicine because a thorough understanding of these topics is of utmost importance in the interpretation of medical literature and applicability of the results therein. Basic principles of valid clinical research and components of clinical trials are reviewed. The chapter explores specific topics pertaining to the designing, reporting, and interpreting of clinical studies about the treatment of pain. The effects of the analysis on the clinical applicability of study results are discussed. Finally, it identifies special features specific to the study of pain. A number of references are provided for further reading.


CJEM ◽  
1999 ◽  
Vol 1 (01) ◽  
pp. 37-38 ◽  
Author(s):  
Michael Bullard ◽  
David Rhine

Our CJEM Journal Club consists of two sections. The first, “Critically Appraised Topics,” is devoted to evidence-based reviews of specific EM-related questions. Questions will be answered by using a focused literature review and presenting the results in a CAT (Critically Appraised Topic) format. The aims of this section are to address clinical or administrative questions, to demonstrate the application of evidence-based medicine methods in answering such questions, and to accumulate a CAT database for emergency physicians.


Sign in / Sign up

Export Citation Format

Share Document