Desires, demand, perceptions, and knowledge of assisted reproductive technologies of HIV-positive women of reproductive age in ontario, Canada

Autoimmunity of the thyroid gland (TAI) or its dysfunction is quite common among women of reproductive age, and there are suggestions in the literature that they are associated with an unfavorable level of fertility and a negative outcome of pregnancy, as in the case of spontaneous conception or after assisted reproductive technologies (ART). This assumption makes it necessary to screen autoantibodies to thyrotropin (TSH) and thyroid peroxidase among infertile women who have made a number of attempts to become pregnant. Some authors have conducted a number of studies where they have examined the relationship between autoimmunity of the thyroid gland, thyroid function, and fertility. However, there is currently no consensus on the upper limit of the norm for TSH to determine thyroid dysfunction and the limits for intervention. Despite the recent update of the American thyroid Association (ATA) on guidelines for the diagnosis and treatment of thyroid diseases during pregnancy and the postpartum period, many issues remain unresolved in ART. The author came to the following conclusions: open thyroid dysfunction often leads to menstrual disorders, fertility problems, and pregnancy complications, and therefore should be treated accordingly. Currently, there is little evidence to recommend treatment with levothyroxine at TSH levels between 2.5 and 4.0 MMU / l, given the possible side effects of overtreatment, especially in patients with mild thyroid dysfunction. We suggest careful longitudinal monitoring, especially in the presence of thyroid antibodies in women undergoing ART. The 4 MMU / l limit for TSH appears as the intervention level for SCH treatment in women with and without transabdominal utrasound in ART.

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Fertility Desires and Intentions of HIV-Positive Women of Reproductive Age in Ontario, Canada: A Cross-Sectional Study

10.32920/14636388 ◽

2021 ◽

Author(s):

Mona Loutfy ◽

Trevor A. Hart ◽

Saira S. Mohammed ◽

DeSheng Su ◽

Edward D. Ralph ◽

...

Keyword(s):

Cross Sectional Study ◽

Fertility Intentions ◽

Reproductive Age ◽

Hiv Positive ◽

Sectional Study ◽

Women Of Reproductive Age ◽

Cross Sectional ◽

Pregnancy Planning ◽

Fertility Desires ◽

Hiv Positive Women

Background: Improvements in life expectancy and quality of life for HIV-positive women coupled with reduced vertical transmission will likely lead numerous HIV-positive women to consider becoming pregnant. In order to clarify the demand, and aid with appropriate health services planning for this population, our study aims to assess the fertility desires and intentions of HIV-positive women of reproductive age living in Ontario, Canada. Methodology/Principal Findings: A cross-sectional study with recruitment stratified to match the geographic distribution of HIV-positive women of reproductive age (18–52) living in Ontario was carried out. Women were recruited from 38 sites between October 2007 and April 2009 and invited to complete a 189-item self-administered survey entitled ‘‘The HIV Pregnancy Planning Questionnaire’’ designed to assess fertility desires, intentions and actions. Logistic regression models were fit to calculate unadjusted and adjusted odds ratios of significant predictors of fertility intentions. The median age of the 490 participating HIV-positive women was 38 (IQR, 32–43) and 61%, 52%, 47% and 74% were born outside of Canada, living in Toronto, of African ethnicity and currently on antiretroviral therapy, respectively. Of total respondents, 69% (95% CI, 64%–73%) desired to give birth and 57% (95% CI, 53%–62%) intended to give birth in the future. In the multivariable model, the significant predictors of fertility intentions were: younger age (age,40) (p,0.0001), African ethnicity (p,0.0001), living in Toronto (p = 0.002), and a lower number of lifetime births (p = 0.02). Conclusions/Significance: The proportions of HIV-positive women of reproductive age living in Ontario desiring and intending pregnancy were higher than reported in earlier North American studies. Proportions were more similar to those reported from African populations. Healthcare providers and policy makers need to consider increasing services and support for pregnancy planning for HIV-positive women. This may be particularly significant in jurisdictions with high levels of African immigration.

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Our experience of appying Plasmolifting technology (Plasmoliftingtm) in treatment of infertility in women

HEALTH OF WOMAN ◽

10.15574/hw.2016.115.152 ◽

2016 ◽

pp. 152-154

Author(s):

Yu.P. Bogoslav ◽

◽

I.D. Gulmamedova ◽

R.R. Ahmerov ◽

A.M. Yakovets ◽

...

Keyword(s):

Key Words ◽

Assisted Reproductive Technologies ◽

Endometrial Thickness ◽

Reproductive Technologies ◽

Infertility Treatment ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Autologous Plasma ◽

Treatment Methods ◽

Infertile Patients

The objective: to improve the efficiency of infertility treatment methods with the help of assisted reproductive technologies by supplementing a set of preparatory measures with autoplasma treatment via the PlasmoliftingTM technology. Patients and methods. The study involved 93 women of reproductive age (63 infertile patients prepared for IVF, and 30 healthy women). Results. The use of autologous plasma in compliance with the developed technology allowed to increase significantly the number of oocytes and endometrial thickness in IVF cycle, resulting in increased procedure efficiency by 10%. Conclusions. We recommend the use of autologous plasma under the developed technology in women while preparing for the IVF cycle. Key words: female infertility, IVF, autoplasma, Plasmolifting.

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