scholarly journals 333. Non-Invasive In Vivo Imaging of Somatostatin Receptor 2 Gene Transfer with Positron Emission Tomography

2009 ◽  
Vol 17 ◽  
pp. S129
Keyword(s):  
Positron Emission Tomography ◽  
Gene Transfer ◽  
In Vivo Imaging ◽  
Somatostatin Receptor ◽  
Emission Tomography ◽  
Non Invasive ◽  
Positron Emission

scholarly journals Correction to: In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Johannes Notni ◽  
Florian T. Gassert ◽  
Katja Steiger ◽  
Peter Sommer ◽  
Wilko Weichert ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Positron Emission Tomography ◽  
In Vivo Imaging ◽  
Emission Tomography ◽  
Early Stages ◽  
Positron Emission ◽  
Α5β1 Integrin

Following publication of the original article [1], the authors have reported an error in the ‘Histopathology’ (under ‘Materials and methods’) section of the article that compromises the reproducibility of the paper.

scholarly journals In Vivo Imaging of Insulin Receptors in Monkeys Using 18F-Labeled Insulin and Positron Emission Tomography

Diabetes ◽  
1992 ◽  
Vol 41 (7) ◽  
pp. 855-860 ◽  
Author(s):  
R. C. Eastman ◽  
R. E. Carson ◽  
K. A. Jacobson ◽  
Y. Shai ◽  
M. A. Channing ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
In Vivo Imaging ◽  
Insulin Receptors ◽  
Emission Tomography ◽  
Positron Emission

scholarly journals Cre/lox-assisted non-invasive in vivo tracking of specific cell populations by positron emission tomography

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Martin Thunemann ◽  
Barbara F. Schörg ◽  
Susanne Feil ◽  
Yun Lin ◽  
Jakob Voelkl ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Cell Populations ◽  
Specific Cell ◽  
Non Invasive ◽  
Positron Emission

scholarly journals In vivo imaging of therapy response to a novel Pan-HER antibody mixture using FDG and FLT positron emission tomography

Oncotarget ◽  
2015 ◽  
Vol 6 (35) ◽  
pp. 37486-37499 ◽  
Author(s):  
Carsten H. Nielsen ◽  
Mette M. Jensen ◽  
Lotte K. Kristensen ◽  
Anna Dahlman ◽  
Camilla Fröhlich ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
In Vivo Imaging ◽  
Therapy Response ◽  
Emission Tomography ◽  
Positron Emission ◽  
Antibody Mixture

Abstract 460: 64 Cu-DOTATATE for in vivo Positron Emission Tomography Imaging of Somatostatin Receptor 2 Expressing Macrophages in a Göttingen Minipig Model of Atherosclerosis

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Sune Folke Pedersen ◽  
Trine Pagh Ludvigsen ◽  
Andreas Vegge ◽  
Camilla Schumacher-Petersen ◽  
Rasmus Sejersten Ripa ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Abdominal Aorta ◽  
Right Atrium ◽  
Plasma Lipids ◽  
Somatostatin Receptor ◽  
Emission Tomography ◽  
Activated Macrophages ◽  
Lean Control ◽  
Positron Emission

Background: Somatostatin receptor subtype 2 (SSTR 2 ) is expressed by activated macrophages which are important effector cells in atherogenesis and a major constituent of atherosclerotic plaques. SSTR 2 can be targeted non-invasively in vivo using the tracer 64 Cu-DOTATATE and positron emission tomography (PET). Methods: Male castrated Göttingen minipigs were treated according to two diet regimes for 43 weeks: chow (lean control; n=1) or high-fat/high-cholesterol diet (HFHC, obese group; n=2). Plasma lipids: total cholesterol (TC) and triglycerides (TG) were measured and SSTR 2 expression was assessed using hybrid positron emission tomography/magnetic resonance (PET/MR) imaging of the abdominal aorta, one hour (range: 60-63 minutes) post injection with 200 MBq (range 202-214 MBq) of 64 Cu-DOTATATE. Consectutive regions of interest (ROIs) were drawn guided by MR to include vessel wall and lumen of the abdominal aorta to calculate standardized uptake values (SUVs). Target-to-background (TBR) ratios were calculated using right atrium SUVs for blood pool correction (SUV vessel /SUV right atrium = TBR) and reported as mean and maximal values (TBR mean ; TBR max ). Results: Three minipigs (age 17 months) were included and PET/MR was completed in all animals. Mean uptake of 64 Cu-DOTATATE was lowest for the abdominal aorta in the lean control: TBR mean = 0.44 and TBR max = 0.73 (range: TBR mean = 0.29 - 0.62; TBR max = 0.49 - 1.10) and highest in the HFHC group: TBR mean = 0.66 and TBR max = 1.28 (range: TBR mean = 0.26 - 1.38; TBR max = 0.39 - 3.19). Plasma lipids: lean control: TC = 1.34 mmol/L; TG = 0.38 mmol/L; HFHC group (mean values): TC = 18.7mmol/L (range: 11.6 - 25.8mmol/L); TG = 0.6 mmol/L (range: 0.37 - 0.83mmol/L). Conclusion: Non-invasive 64 Cu-DOTATATE PET/MR is feasible for assessment of SSTR 2 expression in a Göttingen minipig model of diet-induced atherosclerosis. Additional studies are needed including assessment of histology findings and gene expression to confirm the presence of activated macrophages in order to validate the use of 64 Cu-DOTATATE PET/MR in this model.

scholarly journals In vivo imaging of synaptic loss in Alzheimer’s disease with [18F]UCB-H positron emission tomography

2019 ◽  
Vol 47 (2) ◽  
pp. 390-402 ◽  
Author(s):  
Christine Bastin ◽  
Mohamed Ali Bahri ◽  
François Meyer ◽  
Marine Manard ◽  
Emma Delhaye ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Positron Emission Tomography ◽  
In Vivo Imaging ◽  
Emission Tomography ◽  
Synaptic Loss ◽  
Positron Emission

Design, Radiosynthesis, and Biodistribution of a New Potent and Selective Ligand for in Vivo Imaging of the Adenosine A2AReceptor System Using Positron Emission Tomography

2000 ◽  
Vol 43 (23) ◽  
pp. 4359-4362 ◽  
Author(s):  
Sergio Todde ◽  
Rosa Maria Moresco ◽  
Pasquale Simonelli ◽  
Pier Giovanni Baraldi ◽  
Barbara Cacciari ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
In Vivo Imaging ◽  
Emission Tomography ◽  
Positron Emission ◽  
Selective Ligand

In vivo imaging of adenovirus-mediated over-expression of dopamine D2 receptors in rat striatum by positron emission tomography

Neuroreport ◽  
2000 ◽  
Vol 11 (4) ◽  
pp. 743-748 ◽  
Author(s):  
Osamu Ogawa ◽  
Hiroyuki Umegaki ◽  
Kiichi Ishiwata ◽  
Yukako Asai ◽  
Hiroyuki Ikari ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
In Vivo Imaging ◽  
D2 Receptors ◽  
Dopamine D2 Receptors ◽  
Emission Tomography ◽  
Rat Striatum ◽  
Over Expression ◽  
Dopamine D2 ◽  
Positron Emission
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