144Ce in Tissues of Beagle Dogs After Inhalation of CeCl3 with Special Emphasis on Endocrine Glands and Reproductive Organs

1976 ◽  
Vol 30 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Richard G. Cuddihy ◽  
Bruce B. Boecker ◽  
Roger O. McClellan ◽  
George M. Kanapilly
Keyword(s):  
Reproductive Organs ◽  
Endocrine Glands ◽  
Beagle Dogs

scholarly journals Clinical and structural changes in reproductive organs and endocrine glands of sterile cows

2020 ◽  
Vol 13 (4) ◽  
pp. 774-781
Author(s):  
Evgeny Skovorodin ◽  
Ravil Mustafin ◽  
Svetlana Bogoliuk ◽  
George Bazekin ◽  
Valian Gimranov
Keyword(s):  
Structural Changes ◽  
Functional System ◽  
Reproductive Organs ◽  
Essential Elements ◽  
Corpora Lutea ◽  
Endocrine Glands ◽  
Ovarian Dysfunction ◽  
Republic Of Bashkortostan ◽  
The Republic ◽  
Pars Anterior

Aim: The study aimed to determine both macroscopic and microscopic changes in the reproductive organs of sterile cows. Materials and Methods: Careful clinical and gynecological examinations (using histological and histochemical methods) of organs of culled sterile cows, such as ovaries, oviducts, the uterus, pars anterior adenohypophysis, thyroid body, and adrenals, were performed. Results: It was found that 20% of the examined cows in the farms of the Republic of Bashkortostan had pathology of reproductive organs. Ovarian dysfunction was diagnosed in 31% of sterile cows. Histological and histochemical studies revealed that high atresia of all types of ovarian follicles is associated with hypofunction of the ovaries. This was related to stromal vascular dystrophy and was accompanied by atrophy of thecal endocrine elements, resulting in decrease of endocrine and generative function of ovaries. Conclusion: Essential elements of the ovarian dysfunction pathogenesis are disorders of the functional system "ovary-pituitary-adrenal-thyroid gland" and the abnormality of utero-ovarian relationships, which differ significantly during hypofunction, in case of follicular cysts, and in case of persistent corpora lutea. This difference in abnormalities of utero-ovarian relationships should be considered when developing diagnostic and treatment methods and determining preventive measures.

Spontaneous lesions in endocrine glands of experimental Wistar rats and beagle dogs

2016 ◽  
Vol 68 (1) ◽  
pp. 1-13 ◽  
Author(s):  
G.J. Nataraju ◽  
Ramchandra K. Ranvir ◽  
Viren R. Kothule ◽  
Shekhar B. Kadam ◽  
B.V. Ravichandra ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Endocrine Glands ◽  
Beagle Dogs

A Study of the Relation between the Reproductive Organs and Dementia Præcox

1920 ◽  
Vol 66 (275) ◽  
pp. 414-422 ◽  
Author(s):  
T. Matsumoto ◽  
Frederick W. Mott
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Medical Journal ◽  
British Medical Journal ◽  
Reproductive Organs ◽  
Dementia Praecox ◽  
Endocrine Glands ◽  
Full Report ◽  
The Central Nervous System

Dr. Matsumoto, who came to study neuro-pathology under my direction, having acquired a thorough knowledge of the methods employed in investigating the histology of the central nervous system and the endocrine glands, expressed a desire to study the microscopic specimens which I had prepared during the last six years of the testes and resicula: seminales in one hundred cases of all ages dying in hospitals and asylums from injury or disease. A full report of this work was published in theBritish Medical Journalof November 22nd, 29th, and December 6th, 1919.

scholarly journals EFFECT OF FEEDING THE PINEAL BODY UPON THE DEVELOPMENT OF THE ALBINO RAT

1920 ◽  
Vol 31 (3) ◽  
pp. 335-344 ◽  
Author(s):  
Warren R. Sisson ◽  
John M. T. Finney
Keyword(s):  
Microscopic Examination ◽  
Reproductive Organs ◽  
Developmental Changes ◽  
Pineal Body ◽  
Albino Rats ◽  
Endocrine Glands ◽  
Albino Rat ◽  
Microscopic Studies ◽  
And Control ◽  
Effect Of Feeding

The pineal body of young calves was fed to albino rats beginning at the age of 3 weeks and extending over periods of from 3 to 6 weeks. Four litters of rats were used. Of these, fourteen rats were fed the pineal powder and ten were used as control subjects. Observations in regard to developmental changes and microscopic examination of the endocrine glands and reproductive organs were made. The pineal-fed rats of the first two litters remained somewhat smaller than their controls. The pineal-fed and control animals of Litters 3 and 4 showed no differences in development. Microscopic studies showed no differences between pineal-fed and control rats. We may therefore conclude that feeding the desiccated pineal body of young calves to young albino rats fails to produce any effect upon the early development of these animals.

scholarly journals The ED/TEG Indicator for the Identification of Endocrine Disrupting or Toxic Effects on Endocrine Glands of Crop Protection Products Used in Organic and Conventional Agriculture in France

2021 ◽  
Vol 18 (7) ◽  
pp. 3477
Author(s):  
Adèle Paul ◽  
Johan Spinosi ◽  
Mounia El Yamani ◽  
Anne Maitre ◽  
Barbara Charbotel
Keyword(s):  
Health Outcomes ◽  
Crop Protection ◽  
Reproductive Organs ◽  
Health Concern ◽  
Endocrine Glands ◽  
Level Of Evidence ◽  
Conventional Agriculture ◽  
Endocrine Disrupting ◽  
Epidemiological Tool ◽  
High Concern

Studying the human health impacts of pesticides and their endocrine disruptor (ED) effects is a public health concern. The aim of this study is to identify phytopharmaceutical active substances (PAS) that are an ED or are toxic on endocrine glands (TEG), and to propose an ED/TEG effect indicator. Five international official databases were analyzed to identify the occurrence of health outcomes for 458 PAS. Health outcomes targeting seven endocrine systems were selected. For each substance, the level of evidence of the collected information and the number of outcomes were used to affect a level of concern about ED/TEG effects. Among the substances studied, 10% had a global ED/TEG effect classified as ‘high concern’, 55% as ‘medium concern’, 9% as ‘low concern’, and 26% as ‘unknown’. Ten of the high ED/TEG concern substances and 170 medium or low concern substances were licensed in 2018 in France. The outcomes were mainly on the reproductive organs, thyroid, and adrenal glands. Eight of the 41 biocontrol products studied were classified: 5 were ‘high’ or ‘medium concern’ and 3 had ‘unknown effect’. Although the proposed ED/TEG indicator is not an official classification, it can be used as an epidemiological tool for classifying the occupational and environmental risks of substances in retrospective population studies and be useful for occupational health physicians.

The Clinical, Roentgenological and Morphological Effects of an Acute Exposure of Phosgene on the Lungs of Dogs

1971 ◽  
Vol 29 ◽  
pp. 236-237
Author(s):  
R. F. Bils ◽  
W. F. Diller ◽  
F. Huth
Keyword(s):  
Latent Period ◽  
Chemical Industry ◽  
Toxic Substance ◽  
Lung Edema ◽  
X Rays ◽  
Beagle Dogs ◽  
Male And Female ◽  
Morphological Alterations ◽  
Before And After ◽  
Electron Microscopes

Phosgene still plays an important role as a toxic substance in the chemical industry. Thiess (1968) recently reported observations on numerous cases of phosgene poisoning. A serious difficulty in the clinical handling of phosgene poisoning cases is a relatively long latent period, up to 12 hours, with no obvious signs of severity. At about 12 hours heavy lung edema appears suddenly, however changes can be seen in routine X-rays taken after only a few hours' exposure (Diller et al., 1969). This study was undertaken to correlate these early changes seen by the roengenologist with morphological alterations in the lungs seen in the'light and electron microscopes.Forty-two adult male and female Beagle dogs were selected for these exposure experiments. Treated animals were exposed to 94.5-107-5 ppm phosgene for 10 min. in a 15 m3 chamber. Roentgenograms were made of the thorax of each animal before and after exposure, up to 24 hrs.

Ultrastructural aspects of gymnosperms reproductive organs tissues due to their functional condition

1978 ◽  
Vol 36 (2) ◽  
pp. 440-441
Author(s):  
G. M. Kozubov
Keyword(s):  
Metabolic Activity ◽  
Functional Condition ◽  
Reproductive Organs ◽  
Considerable Change ◽  
Complicated Structure ◽  
Tetrad Stage ◽  
Ubisch Bodies ◽  
Similar Organization ◽  
Female Reproductive Organs ◽  
High Metabolic Activity

The ultrastructure of reproductive organs of pine, spruce, larch and ginkgo was investigated. It was found that the male reproductive organs possess similar organization. The most considerable change in the ultrastructure of the microsporocytes occur in meiosis. Sporoderm is being laid at the late tetrad stage. The cells of the male gameto-phyte are distinguished according to the metabolic activity of the or- ganells. They are most weakly developed in the spermiogenic cell. Ta-petum of the gymnosperms is of the periplasmodic - secretorial type. The Ubisch bodies which possess similar structure in the types investigated but are specific in details in different species are produced in tapetum.Parietal and subepidermal layers are distinguished for their high metabolic activity and are capable of the autonomous photosynthesis. Female reproductive organs differ more greatly in their struture and have the most complicated structure in primitive groups. On the first stages of their formation the inner cells of nucellus are transformed into the nucellar tapetum in which the structures similar to the Ubisch bodies taking part in the formation of the sporoderm of female gametophyte have been found.

Intraneuronal accumulations of lysosomes in the cerebellum of rats and dogs after dosing with MDL-832

1990 ◽  
Vol 48 (3) ◽  
pp. 830-831
Author(s):  
S.D. Barnard ◽  
S.D. Warner
Keyword(s):  
Brown Pigment ◽  
Beagle Dogs ◽  
Sprague Dawley ◽  
Gelatin Capsules ◽  
Pigment Granules ◽  
Sprague Dawley Rats ◽  
Hematoxylin And Eosin ◽  
Dose Levels

1, 2, 9, 10-tetramethoxyaporphine phosphate (MDL-832) was once considered a potential human antitussive. MDL-832 was administered orally in the diets of Sprague-Dawley rats at dose levels of 0, 5, 10, 20, 40, 80 and 160 mg/kg/day for 3 and 6 months and in gelatin capsules to Beagle dogs at 0, 5, 10, 15, 30 and 60 mg/kg/day for 3, 6 and 12 months. Histopathologic examinations of hematoxylin and eosin-stained cerebellar sections revealed intracytoplasmic brown pigment accumulations in large fusiform neurons (presumably the motor type) of the pons. The pigment granules were found to be PAS-positive, non-acid fast, iron-free, Sudan B-positive and fuchsinophilic. Intraneuronal pigment accumulations were seen in rats after 3 months of treatment at 80 mg but not at 40 mg and after 6 months at 20 mg but not at 10 mg. For dogs the effect was observed after 3 months at 60 mg but not at 30 mg and after 12 months at 10 mg but not at 5 mg.

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