scholarly journals Underlying factors that influence the acceptance of COVID-19 vaccine in a country with a high vaccination rate

Author(s):  
Daniela Toro-Ascuy ◽  
Nicolas Cifuentes-Munoz ◽  
Andrea Avaria ◽  
Camila Pereira-Montecinos ◽  
Gilena Cruzat ◽  
...  

Control of the COVID-19 pandemic largely depends on the effectiveness of the vaccination. Several factors including vaccine hesitancy can affect the vaccination process. Understanding the factors that underlie the willingness to accept vaccination brings pivotal information to control the pandemic. We analyzed the association between the willingness level to accept the COVID-19 vaccine, and vaccine determinants amidst the Chilean vaccination process. Individual-level survey data was collected from nationally representative samples of 744 respondents, and multivariate regression models used to estimate the association between outcome and explanatory variables. Trust in the COVID-19 vaccine, scientists, and medical professionals were found to increase the willingness to: accept the vaccine, a booster dose, annual vaccination, and children vaccination. Our results are critical to understanding the acceptance of COVID-19 vaccines in the context of a country with one of the highest vaccination rates in the world. We provide information for decision-making, policy design and communication of vaccination programs.

2021 ◽  
Author(s):  
Byungkyu Lee ◽  
James Chu

Vaccine hesitancy is a critical barrier to widespread vaccination uptake and containment of the COVID-19 pandemic. In the United States, vaccines have become politically polarized, with high rates of vaccine hesitancy observed among Republicans. In contrast to prior research focusing on partisan gaps, we investigate vaccination attitudes and uptake among a group overlooked in prior research: those who are eligible to vote but did not register in the presidential elections. Drawing on nationally representative and longitudinal survey data from April 2020 to October 2021, we show that this group – whom we call “political outsiders” – represents about 16% of the U.S. population. They had the lowest vaccination rate (47%) by 2021 October, significantly lower than Republican (65%), Independent (76%), and Democratic voters (88%). Further, we find that political outsiders are less likely to trust physicians compared to other partisan groups. Because the sources they trust differ from partisans, existing public health messaging may be less likely to reach them successfully. Finally, we find that political outsiders experience more socio-economic hardships and are less integrated into society. Hence, our results underscore the importance of targeted efforts to reach this highly vulnerable population.


2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
João Gentil

Abstract Background In 2019, WHO classified vaccine hesitancy as one of the top 10 threats to global health. Vaccination is an area of excellence in nursing that has gained a new focus and has become a challenge in the provision of care and in the management field. Vaccine hesitation raises questions about mandatory vaccination, individual versus collective freedom that are highlighted in the current context due to the emergence of new vaccines. In this paper, we want to analyze and update knowledge about vaccines hesitancy from an ethical and bioethical perspective. Methods A combination of literature reviews on vaccine refusal/hesitancy, ethics and COVID-19 vaccine confidence, accessed on SciELO and PubMed databases and analysis of documents from General Directorate of Health and Ordem dos Enfermeiros (National Nurses Association). Results Vaccination programs aim is a collective protection. The desirable effects at individual level do not have the same ethical value at collective level, leading to cost-benefit imbalances. Moral conflicts between the individual and the collective, cost-benefit imbalances and the insufficiency of bioethics principles, lead us to the use of other moral values and principles, such as responsibility, solidarity and social justice, as a tool for ethical reflection problems related to COVID-19 vaccines. Conclusions There are no perfect solutions to ethical dilemmas and some optimal solutions could depend the context. In a pandemic situation, one of the most relevant ethical issues is the herd immunity since it leaves public health at risk. Equity and the principle of justice in vaccination campaign are shown daily in the nursing profession.


Author(s):  
Abolfazl Mollalo ◽  
Moosa Tatar

Vaccine hesitancy refers to delay in acceptance or refusal of vaccines despite the availability of vaccine services. Despite the efforts of United States healthcare providers to vaccinate the bulk of its population, vaccine hesitancy is still a severe challenge that has led to the resurgence of COVID-19 cases to over 100,000 people during early August 2021. To our knowledge, there are limited nationwide studies that examined the spatial distribution of vaccination rates, mainly based on the social vulnerability index (SVI). In this study, we compiled a database of the percentage of fully vaccinated people at the county scale across the continental United States as of 29 July 2021, along with SVI data as potential significant covariates. We further employed multiscale geographically weighted regression to model spatial nonstationarity of vaccination rates. Our findings indicated that the model could explain over 79% of the variance of vaccination rate based on Per capita income and Minority (%) (with positive impacts), and Age 17 and younger (%), Mobile homes (%), and Uninsured people (%) (with negative effects). However, the impact of each covariate varied for different counties due to using separate optimal bandwidths. This timely study can serve as a geospatial reference to support public health decision-makers in forming region-specific policies in monitoring vaccination programs from a geographic perspective.


2021 ◽  
Author(s):  
Fang Fang ◽  
John David Clemens ◽  
Zuo-Feng Zhang ◽  
Timothy F. Brewer

Background: Despite safe and effective vaccines to prevent Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections and disease, a substantial minority of the US remains resistant to getting vaccinated. It is imperative to know if expanding vaccination rates could reduce community-wide Coronavirus 2019 (COVID-19) disease, not just among those vaccinated. Methods: Negative binomial models were used to estimate associations between U.S. county-level vaccination rates and county-wide COVID-19 incidence and mortality between April 23rd and September 30th, 2021. A two-week lag and a four-week lag were introduced to assess vaccination rate impact on incidence and mortality, respectively. Stratified analyses were performed for county vaccination rates >40%, and before and after Delta became the dominant variant. Findings: Among 3,070 counties, each percentage increase in population vaccination rates reduced county-wide COVID-19 incidence by 0.9% (relative risk (RR) 0.9910 (95% CI: 0.9869, 0.9952)) and mortality by 1.9% (RR 0.9807 (95% CI: 0.9745, 0.9823)). Among counties with vaccination coverage >40%, each percentage increase in vaccination rates reduced COVID-19 disease by 1.5%, RR 0.9850 (95% CI: 0.9793, 0.9952) and mortality by 2.7% (RR 0.9727 (95% CI: 0.9632, 0.9823)). These associations were not observed among counties with <40% vaccination rates. Increasing vaccination rates from 40% to 80% would have reduced COVID-19 cases by 45.4% (RR 0.5458 (95% CI: 0.4335, 0.6873)) and deaths by 67.0% (RR 0.3305 (95% CI: 0.2230, 0.4898)). An estimated 5,989,952 COVID-19 cases could have been prevented and 127,596 lives saved had US population vaccination rates increased from 40% to 80%. Interpretations: Increasing U.S. SARS-CoV-2 vaccination rates results in population-wide reductions in COVID-19 incidence and mortality. Furthermore, increasing vaccination rates above 40% has protective effects among non-vaccinated persons. Given ongoing vaccine hesitancy in the U.S., increasing vaccination rates could better protect the entire community and potentially reach herd immunity. Funding: National Cancer Institute


2021 ◽  
Author(s):  
David Lazer ◽  
Katherine Ognyanova ◽  
Matthew Baum ◽  
James Druckman ◽  
Jon Green ◽  
...  

Who has been most likely to be vaccinated? And who is most likely to be vaccine resistant? Among the early, eligible individuals, who has received the vaccine, and who has refused to be vaccinated? In this report we address these questions by examining the relationship between various sociodemographic categories and vaccination rates, vaccination resistance, vaccination hesitancy, vaccine accessibility, and vaccine refusal. We examine both the current state of these relationships, as well as changes in vaccine resistance over time. We find strong relationships between these vaccine outcomes at the individual level and age, education, income, race, partisanship, gender, and urbanicity. All of these relationships are statistically significant in a multivariable analysis; but education stands out as a particularly powerful predictor. The divergent vaccination rate likely partially reflects the complex distribution process for the vaccine that has hurt those with the least resources and knowledge to navigate that complexity. Further, the emphasis in many states on mass vaccination sites reduces the contact of vaccine skeptics with the person best able to discuss the benefits and risks of vaccination: their primary care physicians.


Vaccines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1153
Author(s):  
Marcin Piotr Walkowiak ◽  
Dariusz Walkowiak

The high effectiveness of a vaccination-promotion campaign, which may be measured by the number of those successfully convinced to get vaccinated, is a key factor in combating the COVID-19 pandemic. This, however, appears to be linked to the precise identification of the underlying causes for vaccine hesitancy behaviours. Based on a regression model (adjusted R2 of 0.78) analysing 378 sub-regions of Poland, we showed that such behaviours, even when going against the party agenda, can be indirectly yet precisely gauged predominantly through voting patterns. Additionally, education and population density were found to be positively related to low vaccine hesitancy, while markers of social exclusion, both external (employment rate) and psychological (voter turnout) ones, affected it negatively. In the second, follow-up part of our study, which analyses the changes that took place in two months (adjusted R2 of 0.53), we found a further increase in vaccination rate to be positively related to the number of those already vaccinated and to the political views of the population, and negatively related to its level of education. In both cases, there was a surprisingly weak relationship between the potential markers of accessibility and vaccination rate. In spite of the known overall differences in vaccination rates for different age and sex groups, these variables did not have any additional informative value in explaining the observed regional differences.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Anisah B. Bagasra ◽  
Sara Doan ◽  
Christopher T. Allen

Abstract Background Previous research has indicated that demographic differences affect COVID-19 vaccination rates. Trust, in both the vaccine itself and institutional trust, is one possible factor. The present study examines racial differences in institutional trust and vaccine status among a nationally representative sample of adults in the United States. Methods Data for the current study was collected as part of Wave 8 Omnibus 2000 survey conducted by RAND ALP and consisted of 2080 participants. Responses were collected through the online RAND ALP survey in March 2021. Results Trust in the scientific community was the strongest predictor for already receiving at least one dose of the COVID-19 vaccine at the time of study. Asians had a significantly higher trust in the scientific community compared to all other groups. Results also showed a significant difference in level of trust of the government’s response to the COVID-19 pandemic with Indian/Alaskan Natives reporting lower trust compared to Whites, Blacks and Asians. Asians also had a significantly higher level of trust when compared to those who identified as racial Other. Those who identify as American Indian/Alaskan Natives had the lowest levels of institutional trust. Trust in the government’s response was not indicative of vaccination within the sample. Conclusions Strategies to increase trust of the scientific community can be employed to address vaccine hesitancy through community-based initiatives and building of partnerships between the scientific community and local community stakeholders.


Author(s):  
Mary Fossen ◽  
Margaret Bethany ◽  
Sanjay Modak ◽  
Sally Parris ◽  
Rohit Modak

Abstract Objective: To compare COVID-19 vaccine hesitancy among hospital employees by demographics. Methods: Our institution has offered an mRNA COVID-19 vaccine to all employees since January 2021. We collected data on vaccination rates among hospital employees and looked for differences in demographic groups to determine in which groups vaccine hesitancy is the highest. Those who received at least one dose of vaccine were considered “vaccinated” for this study. Results: There was a 71% vaccination rate among all hospital employees as of March 10, 2021. Age over 50 (odds ratio 1.85, 95% CI 1.53 to 2.24, p<0.01), working in a clinical department (odds ratio 1.19, 95% CI 1.01 to 1.42, p = 0.02), and white race compared to black/African American race (odds ratio 4.55, 95% CI 3.74 to 5.52, p<0.01) were all significant factors for receiving vaccination. Gender (odds ratio 1.12, 95% CI 0.94 to 1.35, p=0.10) was not significant. Conclusions: In a population with equal access to the COVID-19 vaccine, there were significant differences in vaccination rates among different demographic groups. Employees under 50 years of age, non-clinical employees, and black/African American employees were less likely to be vaccinated. This suggests that attitudes towards vaccination, and not simply access to the vaccine, are factors in vaccination rates.


Vaccines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1284
Author(s):  
Pranav Mirpuri ◽  
Richard A. Rovin

The COVID-19 vaccination effort is a monumental global challenge. Recognizing and addressing the causes of vaccine hesitancy will improve vaccine uptake. The primary objective of this study was to compare the COVID-19 vaccination rates in US counties to historical vaccination rates for influenza in persons aged 65 and older. The secondary objective was to identify county-level demographic, socioeconomic, and political factors that influence vaccination rates. County level data were obtained from publicly available databases for comparison and to create predictive models. Overall, in US counties the COVID-19 vaccination rate exceeded influenza vaccination rates amongst those aged 65 or older (69.4.0% vs. 44%, p < 0.0001). 2690 (83.4%) of 3224 counties had vaccinated 50% or more of their 65 and older residents in the first seven months of the COVID-19 vaccination roll out. There were 467 (14.5%) of 3223 counties in which the influenza vaccination rate exceeded the COVID-19 vaccination rate. Most of these counties were in the Southern region, were considered politically “red” and had a significantly higher non-Hispanic Black resident population (14.4% vs. 8.2%, p < 0.0001). Interventions intended to improve uptake should account for nuances in vaccine access, confidence, and consider factual social media messaging, especially in vulnerable counties.


Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 650 ◽  
Author(s):  
Ronghui Yang ◽  
Bart Penders ◽  
Klasien Horstman

A series of vaccine incidents have stimulated vaccine hesitance in China over the last decade. Many scholars have studied the institutional management of these incidents, but a qualitative study of stakeholders’ perspectives on vaccine hesitancy in China is missing. To address this lacuna, we conducted in-depth interviews and collected online data to explore diverse stakeholders’ narratives on vaccine hesitance. Our analysis shows the different perspectives of medical experts, journalists, parents, and self-defined vaccination victims on vaccination and vaccination hesitance. Medical experts generally consider vaccines, despite some flaws, as safe, and they consider most vaccine safety incidents to be related to coupling symptoms, not to vaccinations. Some parents agree with medical experts, but most do not trust vaccine safety and do not want to put their children at risk. Media professionals, online medical experts, and doctors who do not need to align with the political goal of maintaining a high vaccination rate are less positive about vaccination and consider vaccine hesitance a failure of expert–lay communication in China. Our analysis exhibits the tensions of medical expert and lay perspectives on vaccine hesitance, and suggests that vaccination experts ‘see like a state’, which is a finding consistent with other studies that have identified the over-politicization of expert–lay communication in Chinese public discourse. Chinese parents need space to express their concerns so that vaccination programs can attune to them.


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