<p style="text-align: justify;">Student dropout, defined as the temporary or definitive suspension of the exercise of the right to education, is attributable to multiple variables classified into individual, academic, institutional, and socioeconomic determinants which may be exacerbated in the context of the Coronavirus disease (COVID-19) pandemic. Consequently, this work aims to synthesize, from the available evidence, the behaviour and influence of the explanatory variables of school dropout in infant school, primary school and, high school in Colombia for the period 2014-2019 compared to the period 2020-2021 under the COVID-19 pandemic conditions. The research methodology consisted of a systematic review of 125 indexed articles for 2014-2019 and 32 reports related to dropout in Colombian Basic education for the 2020-2021 period. The systematic review of the 157 articles revealed that dropout was studied and explained in both time periods, mainly from the academic determinant whose most cited explanatory variables were: ‘teachers’, ‘curriculum’ and ‘methodologies used’. Moreover, it could be perceived that in the period 2014-2019, the socioeconomic variable was the second dropout determinant, considering ‘family income” as the most important indicator, while in 2020-2021 the “infrastructure” and the ‘political environment’ remained as the most dominant. Lastly, in 2020-2021, the variable ‘teachers’ was highly cited showing that their practice made students maintain their interest despite the physical distance.</p>