Investigating cell culture dynamics combining high density recordings with dimensional reduction techniques

Author(s):  
Thierry Nieus ◽  
Stefano Di Marco ◽  
Alessandro Maccione ◽  
Hayder Amin ◽  
Luca Berdondini
Author(s):  
Nesrin Sarigul-Klijn ◽  
Israel Lopez ◽  
Seung-Il Baek

Vibration and acoustic-based health monitoring techniques are presented to monitor structural health under dynamic environment. In order to extract damage sensitive features, linear and nonlinear dimensional reduction techniques are applied and compared. First, a vibration numerical study based on the damage index method is used to provide both location and severity of impact damage. Next, controlled scaled experimental measurements are taken to investigate the aeroacoustic properties of sub-scale wings under known damage conditions. The aeroacoustic nature of the flow field in and around generic aircraft wing damage is determined to characterize the physical mechanism of noise generated by the damage and its applicability to battle damage detection. Simulated battle damage is investigated using a baseline, and two damage models introduced; namely, (1) an undamaged wing as baseline, (2) chordwise-spanwise-partial-penetration (SCPP), and (3) spanwise-chordwise-full-penetration (SCFP). Dimensional reduction techniques are employed to extract time-frequency domain features, which can be used to detect the presence of structural damage. Results are given to illustrate effectiveness of this approach.


2011 ◽  
Vol 133 (6) ◽  
Author(s):  
Israel Lopez ◽  
Nesrin Sarigul-Klijn

In this paper, we present a study of dimensional reduction techniques for structural damage assessment of time-varying structures under uncertainty. Discrete tracking of the frequency response and the mode shape curvature index method is employed to perform damage assessment. Assessment of spontaneous damage in deteriorating structures is important as it can have potential benefits in improving their safety and performance. Most of the available damage assessment techniques incorporate the usage of system identification and classification techniques for detecting damage, location, and/or severity; however, much work is needed in the area of dimensional reduction in order to compress the ever-increasing data and facilitate decision-making in damage assessment classification. A comparison of dimensional reduction techniques is presented and evaluated in terms of separating damaged from undamaged data sets under two types of uncertainty, structural deterioration and environmental uncertainties. The use of a recursive principal component analysis for detecting and tracking structural deterioration and spontaneous damage is evaluated via computational simulations. The results of this study reveal that dimensional reduction techniques can greatly enhance structural damage assessment under uncertainties. This paper compares multiple dimensional reduction techniques by identifying their weaknesses and strengths.


2011 ◽  
Vol 88 (8) ◽  
pp. 1702-1706 ◽  
Author(s):  
J.H. Tian ◽  
J. Hu ◽  
F. Zhang ◽  
X. Li ◽  
J. Shi ◽  
...  

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