Disseminated Mycobacterium marinum skin infection due to chronic lymphedema in an immunocompetent patient

2018 ◽  
Vol 16 (5) ◽  
pp. 614-616 ◽  
Author(s):  
Sibylle Schliemann ◽  
Franziska Rässler ◽  
Jörg Tittelbach ◽  
Katharina Kranzer ◽  
Christine Zollmann ◽  
...  
2011 ◽  
Vol 102 (3) ◽  
pp. 236-237
Author(s):  
P. Giráldez ◽  
E. Mayo ◽  
P. Pavón ◽  
A. Losada

2003 ◽  
Vol 185 (5) ◽  
pp. 1745-1748 ◽  
Author(s):  
Jan Rybniker ◽  
Martina Wolke ◽  
Christiane Haefs ◽  
Georg Plum

ABSTRACT Mycobacterium marinum is a close relative of the obligate human pathogen Mycobacterium tuberculosis. As with M. tuberculosis, M. marinum causes intracellular infection of poikilothermic vertebrates and skin infection in humans. It is considered a valid model organism for the study of intracellular pathogenesis of mycobacteria. Low transformation efficiencies for this species have precluded approaches using mutant libraries in pathogenesis studies. We have adapted the conditionally replicating mycobacteriophage phAE94, originally developed as a transposon mutagenesis tool for M. tuberculosis, to meet the specific requirements of M. marinum. Conditions permissive for phage replication in M. tuberculosis facilitated highly efficient transposon delivery in M. marinum. Using this technique we succeeded in generating a representative mutant library of this species, and we conclude that TM4-derived mycobacteriophages are temperature-independent suicide vectors for M. marinum.


2017 ◽  
pp. 325-358
Author(s):  
Domenico Bonamonte ◽  
Angela Filoni ◽  
Michelangelo Vestita ◽  
Gianni Angelini

2015 ◽  
Vol 37 (2) ◽  
pp. 140-143
Author(s):  
Ahmed Anwar Aljowder ◽  
Azad Kareem Kassim ◽  
Mazen Raees

2005 ◽  
Vol 40 (1) ◽  
pp. 206-208 ◽  
Author(s):  
C.-C. Lai ◽  
L.-N. Lee ◽  
Y.-L. Chang ◽  
Y.-C. Lee ◽  
L.-W. Ding ◽  
...  

BMJ ◽  
1971 ◽  
Vol 2 (5760) ◽  
pp. 505-506 ◽  
Author(s):  
G I Barrow ◽  
M Hewitt

Author(s):  
Wendy Uijtendaal ◽  
Rima Yohanna ◽  
Folkert Visser ◽  
Paul Ossenkoppele ◽  
Dorine Hess ◽  
...  

Infection with Mycobacterium marinum is common in fish, and so human infection usually arises from contact with contaminated water or fish. A solitary papulonodular lesion on a finger or hand is the typical presentation. Disseminated infections are rare and mostly seen in immunocompromised patients. We present a rare case of disseminated M. marinum infection presenting with polyarthritis, tenosynovitis, dactylitis, and (sub)cutaneous and intramuscular lesions in an immunocompetent patient. This case was complicated by hypercalcemia, renal failure and eventually death. A contaminated rain barrel was most likely the primary source of the infection.


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