Elucidating interactions of the epoxide ring on Pt(111) by comparing reaction pathways of propylene oxide and 1-epoxy-3-butene

2021 ◽  
Vol 39 (6) ◽  
pp. 063214
Author(s):  
William N. Porter ◽  
Zhexi Lin ◽  
Jingguang G. Chen
2013 ◽  
Vol 781-784 ◽  
pp. 169-173 ◽  
Author(s):  
Wen Yu Zhang ◽  
Jing Guo Li ◽  
Feng Ma ◽  
Xiao Yong Yang

The adsorption of propylene oxide (PO) onto MgO, ZnO and Al2O3was investigated by usingin situ-IR measurements. Detailed mechanisms for PO adsorption onto these metal oxides are proposed. It was found that the PO epoxide ring exhibits two opening tendencies, depending on the acid-base properties of the metal oxide. PO adsorbed onto MgO is preferentially opened at the O-C (1) bond. The epoxide ring provides two ways to open, at the O-C (1) or the O-C(2) bond on Al2O3. PO adsorbed onto ZnO showed no chemical adsorption on its surface.


2019 ◽  
Vol 9 (20) ◽  
pp. 5567-5571 ◽  
Author(s):  
Shengxin Chen ◽  
Guixiang Zeng ◽  
Yingwei Li ◽  
Bin He ◽  
Ruixia Liu ◽  
...  

Ionic liquids (ILs) have been widely introduced recently into the epoxide ring-opening reaction as catalysts or solvent without considering the chemical stability of ILs in propylene oxide (PO).


1968 ◽  
Vol 20 (03/04) ◽  
pp. 588-595 ◽  
Author(s):  
E. B Goodsell ◽  
R. A Krause ◽  
E. T Kimura

SummaryUbiquin (oligo-3-(N-methylmorpholinium)-l,2-propylene oxide chloride) is a stable, water soluble, active heparin antagonist producing prompt neutralization when administered in a 1:1 ratio to rats and dogs. Initial studies indicate that it is devoid of any effect on coagulation per se; nor are there any obvious side effects manifested during the process of neutralization. The acute toxicity is less than that of other compounds in use: toluidine blue, protamine and hexadimethrine.


2019 ◽  
Author(s):  
Clare Bakewell ◽  
Martí Garçon ◽  
Richard Y Kong ◽  
Louisa O'Hare ◽  
Andrew J. P. White ◽  
...  

The reactions of an aluminium(I) reagent with a series of 1,2-, 1,3- and 1,5-dienes are reported. In the case of 1,3-dienes the reaction occurs by a pericyclic reaction mechanism, specifically a cheletropic cycloaddition, to form aluminocyclopentene containing products. This mechanism has been interrogated by stereochemical experiments and DFT calculations. The stereochemical experiments show that the (4+1) cycloaddition follows a suprafacial topology, while calculations support a concerted albeit asynchronous pathway in which the transition state demonstrates aromatic character. Remarkably, the substrate scope of the (4+1) cycloaddition includes dienes that are either in part, or entirely, contained within aromatic rings. In these cases, reactions occur with dearomatisation of the substrate and can be reversible. In the case of 1,2- or 1,5-dienes complementary reactivity is observed; the orthogonal nature of the C=C π-bonds (1,2-diene) and the homoconjugated system (1,5-diene) both disfavour a (4+1) cycloaddition. Rather, reaction pathways are determined by an initial (2+1) cycloaddition to form an aluminocyclopropane intermediate which can in turn undergo insertion of a further C=C π-bond leading to complex organometallic products that incorporate fused hydrocarbon rings.


2018 ◽  
Author(s):  
Victor Laserna ◽  
Tom Sheppard

A versatile approach to the valorization of propargylic alcohols is reported, enabling controlled access to three different products from the same starting materials. Firstly, a general method for the hydroamination of propargylic alcohols with anilines is described using gold catalysis to give 3-hydroxy imines with complete regioselectivity. These 3-hydroxyimines can be reduced to give 1,3-aminoalcohols with high syn seletivity. Alternatively, by using a catalytic quantity of aniline, 3-hydroxyketones can be obtained in high yield directly from propargylic alcohols. Further manipulation of the reaction conditions enables the selective formation of 3-aminoketones via a rearrangement/hydroamination pathway.<br>


2019 ◽  
Author(s):  
Ke-Yin Ye ◽  
Terry McCallum ◽  
Song Lin

Organic radicals are generally short-lived intermediates with exceptionally high reactivity. Strategically, achieving synthetically useful transformations mediated by organic radicals requires both efficient initiation and selective termination events. Here, we report a new catalytic strategy, namely bimetallic radical redox-relay, in the regio- and stereoselective rearrangement of epoxides to allylic alcohols. This approach exploits the rich redox chemistry of Ti and Co complexes and merges reductive epoxide ring opening (initiation) with hydrogen atom transfer (termination). Critically, upon effecting key bond-forming and -breaking events, Ti and Co catalysts undergo proton-transfer/electron-transfer with one another to achieve turnover, thus constituting a truly synergistic dual catalytic system.<br>


1988 ◽  
Author(s):  
L. M. Stock ◽  
J. G. Gatsis ◽  
Kadim Ceylan ◽  
Kofi Ofosu-Asante
Keyword(s):  

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