IBRDM: An Intelligent Framework for Brain Tumor Classification Using Radiomics- and DWT-based Fusion of MRI Sequences

2022 ◽  
Vol 22 (1) ◽  
pp. 1-30
Author(s):  
Rahul Kumar ◽  
Ankur Gupta ◽  
Harkirat Singh Arora ◽  
Balasubramanian Raman

Brain tumors are one of the critical malignant neurological cancers with the highest number of deaths and injuries worldwide. They are categorized into two major classes, high-grade glioma (HGG) and low-grade glioma (LGG), with HGG being more aggressive and malignant, whereas LGG tumors are less aggressive, but if left untreated, they get converted to HGG. Thus, the classification of brain tumors into the corresponding grade is a crucial task, especially for making decisions related to treatment. Motivated by the importance of such critical threats to humans, we propose a novel framework for brain tumor classification using discrete wavelet transform-based fusion of MRI sequences and Radiomics feature extraction. We utilized the Brain Tumor Segmentation 2018 challenge training dataset for the performance evaluation of our approach, and we extract features from three regions of interest derived using a combination of several tumor regions. We used wrapper method-based feature selection techniques for selecting a significant set of features and utilize various machine learning classifiers, Random Forest, Decision Tree, and Extra Randomized Tree for training the model. For proper validation of our approach, we adopt the five-fold cross-validation technique. We achieved state-of-the-art performance considering several performance metrics, 〈 Acc , Sens , Spec , F1-score , MCC , AUC 〉 ≡ 〈 98.60%, 99.05%, 97.33%, 99.05%, 96.42%, 98.19% 〉, where Acc , Sens , Spec , F1-score , MCC , and AUC represents the accuracy, sensitivity, specificity, F1-score, Matthews correlation coefficient, and area-under-the-curve, respectively. We believe our proposed approach will play a crucial role in the planning of clinical treatment and guidelines before surgery.

2021 ◽  
Vol 18 (1) ◽  
pp. 21-27
Author(s):  
Assalah Atiyah ◽  
Khawla Ali

Brain tumors are collections of abnormal tissues within the brain. The regular function of the brain may be affected as it grows within the region of the skull. Brain tumors are critical for improving treatment options and patient survival rates to prevent and treat them. The diagnosis of cancer utilizing manual approaches for numerous magnetic resonance imaging (MRI) images is the most complex and time-consuming task. Brain tumor segmentation must be carried out automatically. A proposed strategy for brain tumor segmentation is developed in this paper. For this purpose, images are segmented based on region-based and edge-based. Brain tumor segmentation 2020 (BraTS2020) dataset is utilized in this study. A comparative analysis of the segmentation of images using the edge-based and region-based approach with U-Net with ResNet50 encoder, architecture is performed. The edge-based segmentation model performed better in all performance metrics compared to the region-based segmentation model and the edge-based model achieved the dice loss score of 0. 008768, IoU score of 0. 7542, f1 score of 0. 9870, the accuracy of 0. 9935, the precision of 0. 9852, recall of 0. 9888, and specificity of 0. 9951.


Author(s):  
Ghazanfar Latif ◽  
Jaafar Alghazo ◽  
Fadi N. Sibai ◽  
D.N.F. Awang Iskandar ◽  
Adil H. Khan

Background: Variations of image segmentation techniques, particularly those used for Brain MRI segmentation, vary in complexity from basic standard Fuzzy C-means (FCM) to more complex and enhanced FCM techniques. Objective: In this paper, a comprehensive review is presented on all thirteen variations of FCM segmentation techniques. In the review process, the concentration is on the use of FCM segmentation techniques for brain tumors. Brain tumor segmentation is a vital step in the process of automatically diagnosing brain tumors. Unlike segmentation of other types of images, brain tumor segmentation is a very challenging task due to the variations in brain anatomy. The low contrast of brain images further complicates this process. Early diagnosis of brain tumors is indeed beneficial to patients, doctors, and medical providers. Results: FCM segmentation works on images obtained from magnetic resonance imaging (MRI) scanners, requiring minor modifications to hospital operations to early diagnose tumors as most, if not all, hospitals rely on MRI machines for brain imaging. In this paper, we critically review and summarize FCM based techniques for brain MRI segmentation.


Author(s):  
V. K. Deepak ◽  
R. Sarath

In the medical image-processing field brain tumor segmentation is aquintessential task. Thereby early diagnosis gives us a chance of increasing survival rate. It will be way much complex and time consuming when comes to processing large amount of MRI images manually, so for that we need an automatic way of brain tumor image segmentation process. This paper aims to gives a comparative study of brain tumor segmentation, which are MRI-based. So recent methods of automatic segmentation along with advanced techniques gives us an improved result and can solve issue better than any other methods. Therefore, this paper brings comparative analysis of three models such as Deformable model of Fuzzy C-Mean clustering (DMFCM), Adaptive Cluster with Super Pixel Segmentation (ACSP) and Grey Wolf Optimization based ACSP (GWO_ACSP) and these are tested on CANCER IMAGE ACHRCHIEVE which is a preparation information base containing High Grade and Low-Grade astrocytoma tumors. Here boundaries including Accuracy, Dice coefficient, Jaccard score and MCC are assessed and along these lines produce the outcomes. From this examination the test consequences of Grey Wolf Optimization based ACSP (GWO_ACSP) gives better answer for mind tumor division issue.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Siyu Xiong ◽  
Guoqing Wu ◽  
Xitian Fan ◽  
Xuan Feng ◽  
Zhongcheng Huang ◽  
...  

Abstract Background Brain tumor segmentation is a challenging problem in medical image processing and analysis. It is a very time-consuming and error-prone task. In order to reduce the burden on physicians and improve the segmentation accuracy, the computer-aided detection (CAD) systems need to be developed. Due to the powerful feature learning ability of the deep learning technology, many deep learning-based methods have been applied to the brain tumor segmentation CAD systems and achieved satisfactory accuracy. However, deep learning neural networks have high computational complexity, and the brain tumor segmentation process consumes significant time. Therefore, in order to achieve the high segmentation accuracy of brain tumors and obtain the segmentation results efficiently, it is very demanding to speed up the segmentation process of brain tumors. Results Compared with traditional computing platforms, the proposed FPGA accelerator has greatly improved the speed and the power consumption. Based on the BraTS19 and BraTS20 dataset, our FPGA-based brain tumor segmentation accelerator is 5.21 and 44.47 times faster than the TITAN V GPU and the Xeon CPU. In addition, by comparing energy efficiency, our design can achieve 11.22 and 82.33 times energy efficiency than GPU and CPU, respectively. Conclusion We quantize and retrain the neural network for brain tumor segmentation and merge batch normalization layers to reduce the parameter size and computational complexity. The FPGA-based brain tumor segmentation accelerator is designed to map the quantized neural network model. The accelerator can increase the segmentation speed and reduce the power consumption on the basis of ensuring high accuracy which provides a new direction for the automatic segmentation and remote diagnosis of brain tumors.


2021 ◽  
Vol 8 ◽  
Author(s):  
Bo Wang ◽  
Jingyi Yang ◽  
Hong Peng ◽  
Jingyang Ai ◽  
Lihua An ◽  
...  

Automatic segmentation of brain tumors from multi-modalities magnetic resonance image data has the potential to enable preoperative planning and intraoperative volume measurement. Recent advances in deep convolutional neural network technology have opened up an opportunity to achieve end-to-end segmenting the brain tumor areas. However, the medical image data used in brain tumor segmentation are relatively scarce and the appearance of brain tumors is varied, so that it is difficult to find a learnable pattern to directly describe tumor regions. In this paper, we propose a novel cross-modalities interactive feature learning framework to segment brain tumors from the multi-modalities data. The core idea is that the multi-modality MR data contain rich patterns of the normal brain regions, which can be easily captured and can be potentially used to detect the non-normal brain regions, i.e., brain tumor regions. The proposed multi-modalities interactive feature learning framework consists of two modules: cross-modality feature extracting module and attention guided feature fusing module, which aim at exploring the rich patterns cross multi-modalities and guiding the interacting and the fusing process for the rich features from different modalities. Comprehensive experiments are conducted on the BraTS 2018 benchmark, which show that the proposed cross-modality feature learning framework can effectively improve the brain tumor segmentation performance when compared with the baseline methods and state-of-the-art methods.


Medical imaging is an emerging field in engineering. As traditional way of brain tumor analysis, MRI scanning is the way to identify brain tumor. The core drawback of manual MRI studies conducted by surgeons is getting manual visual errorswhich can lead toofa false identification of tumor boundaries. To avoid such human errors, ultra age engineering adopted deep learning as a new technique for brain tumor segmentation. Deep learning convolution network can be further developed by means of various deep learning models for better performance. Hence, we proposed a new deep learning algorithm development which can more efficiently identifies the types of brain tumors in terms of level of tumor like T1, T2, and T1ce etc. The proposed system can identify tumors using convolution neural network(CNN) which works with the proposed algorithm “Sculptor DeepCNet”. The proposed model can be used by surgeons to identify post-surgical remains (if any) of brain tumors and thus proposed research can be useful for ultra-age neural surgical image assessments. This paper discusses newly developed algorithm and its testing results.


Brain tumors are the result of unusual growth and unrestrained cell disunity in the brain. Most of the medical image application lack in segmentation and labeling. Brain tumors can lead to loss of lives if they are not detected early and correctly. Recently, deep learning has been an important role in the field of digital health. One of its action is the reduction of manual decision in the diagnosis of diseases specifically brain tumor diagnosis needs high accuracy, where minute errors in judgment may lead to loss therefore, brain tumor segmentation is an necessary challenge in medical side. In recent time numerous ,methods exist for tumor segmentation with lack of accuracy. Deep learning is used to achieve the goal of brain tumor segmentation. In this work, three network of brain MR images segmentation is employed .A single network is compared to achieve segmentation of MR images using separate network .In this paper segmentation has improved and result is obtained with high accuracy and efficiency.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Linmin Pei ◽  
Lasitha Vidyaratne ◽  
Md Monibor Rahman ◽  
Khan M. Iftekharuddin

AbstractA brain tumor is an uncontrolled growth of cancerous cells in the brain. Accurate segmentation and classification of tumors are critical for subsequent prognosis and treatment planning. This work proposes context aware deep learning for brain tumor segmentation, subtype classification, and overall survival prediction using structural multimodal magnetic resonance images (mMRI). We first propose a 3D context aware deep learning, that considers uncertainty of tumor location in the radiology mMRI image sub-regions, to obtain tumor segmentation. We then apply a regular 3D convolutional neural network (CNN) on the tumor segments to achieve tumor subtype classification. Finally, we perform survival prediction using a hybrid method of deep learning and machine learning. To evaluate the performance, we apply the proposed methods to the Multimodal Brain Tumor Segmentation Challenge 2019 (BraTS 2019) dataset for tumor segmentation and overall survival prediction, and to the dataset of the Computational Precision Medicine Radiology-Pathology (CPM-RadPath) Challenge on Brain Tumor Classification 2019 for tumor classification. We also perform an extensive performance evaluation based on popular evaluation metrics, such as Dice score coefficient, Hausdorff distance at percentile 95 (HD95), classification accuracy, and mean square error. The results suggest that the proposed method offers robust tumor segmentation and survival prediction, respectively. Furthermore, the tumor classification results in this work is ranked at second place in the testing phase of the 2019 CPM-RadPath global challenge.


SIMULATION ◽  
2020 ◽  
Vol 96 (11) ◽  
pp. 867-879
Author(s):  
Li Xu ◽  
Qi Gao ◽  
Nasser Yousefi

Brain tumors are a group of cancers that originate from different cells of the central nervous system or cancers of other tissues in the brain. Excessive cell growth in the brain is called a tumor. Tumor cells need food and blood to survive. Growth and proliferation of tumor cells in the cranial space, cause strain inside the brain and thus disrupt vital human structures. Therefore, diagnosis in the early stages of brain tumors is crucial. This study introduces a new optimized method for early diagnosis of the brain tumor. The method has five main parts of noise reduction, tumor segmentation, morphology, feature extraction based on wavelet and gray-level co-occurrence matrix, and classification based on an optimized deep belief network. For optimizing the classifier network, an enhanced version of the moth search algorithm is utilized. Simulation results are applied to three different datasets, FLAIR, T1, and T2, and the accuracy results of the presented method are compared with two other metaheuristics, particle swarm optimization and Bat algorithms. The final results showed that the presented technique has good achievements toward the compared methods.


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