The article presents the social role of Jesuit pharmacies in the Polish-Lithuanian Commonwealth based on the sources of religious provenance and inventories of Jesuit colleges drawn up as a result of the dissolution of the Society of Jesus in 1773. In the first part, the author analyzes the ecclesiastical and secular legislation and its impact on the activities of Jesuit pharmacies. Canon law did not forbid clergymen to deal with medicine, but only limited the possibility of obtaining academic education in this field and conducting surgical procedures. By adopting these rules, Jesuit legislation placed the main emphasis on superiors’ control over the finances of pharmacies and limited the sale of drugs to protect the order from being accused of unfair competition by the townspeople. In the context of state pharmaceutical law, the privilege of June 30, 1662, which allowed for the liberation of journeymen by Jesuit pharmacists, was of great importance. In this way, a path of professional education in the field of pharmacy under the management of the Society, an alternative to the guild system, was created. The second part of the article discusses the social factors that favoured the establishment of monastic pharmacies. Particularly noteworthy is the uneven distribution of Jesuit pharmacies in the former Polish-Lithuanian Commonwealth. While in Royal Prussia the Jesuits did not run pharmacies to avoid conflicts with the Protestant bourgeoisie, in the eastern borderlands of the Polish-Lithuanian state, Jesuit pharmacies were often the only institutions of this type. The third part of the work presents the financial situation of Jesuit pharmacies. They had significant income, but also required considerable investments related to the purchase of raw materials and equipment in the Baltic ports. The fourth part of the article concerns the social scope of the activity of Jesuit pharmacists, who not only provided medicines to the poor, but also treated nobles, magnates and high church dignitaries. Not being obliged by guild regulations, apart from preparing medicines, they also diagnosed them, performed minor surgical procedures and assisted women during childbirth. The last part of the article discusses drugs and raw materials in terms of their availability to the broadly understood clientele. The offer of Jesuit pharmacies included both cheap products derived from the local flora, intended for the treatment of the poor, and expensive raw materials from abroad. Moreover, among the medical matter there were preparations for women and infants, as well as for people suffering from syphilis. In the end, the author emphasizes the centrality of pharmacies in the Jesuit pastoral strategy. Thanks to their high level, pharmacies not only corresponded to the ideal of mercy, but also contributed to gaining the favour and trust of representatives of social elites. In this context, the dissolution of the Society is an important turning point not only in cultural and religious life, but also in the history of medicine and pharmacy in the former Polish-Lithuanian Commonwealth.