Immediate Implants After Enucleation of an Odontogenic Keratocyst: An Early Return to Function

2012 ◽  
Vol 38 (S1) ◽  
pp. 485-488 ◽  
Author(s):  
Sabri C. Isler ◽  
Sabit Demircan ◽  
Taylan Can ◽  
Zerrin Cebi ◽  
Emrah Baca
Keyword(s):  
Aggressive Behavior ◽  
Dental Implants ◽  
Recurrence Rate ◽  
Male Patient ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Histologic Appearance ◽  
Early Return ◽  
Immediate Implants

An odontogenic keratocyst is a unique cyst because of its locally aggressive behavior, high recurrence rate, and characteristic histologic appearance. In this article we present the case of a 22-year-old male patient with a large odontogenic keratocyst and describe his treatment with immediate dental implants.

A Review of the Odontogenic Keratocyst and Report of a Case

2019 ◽  
pp. 1-7
Author(s):  
M. Chandra Sekhar ◽  
D. Ayesha Thabusum ◽  
M. Charitha ◽  
G. Chandrasekhar ◽  
M. Shalini
Keyword(s):  
Recurrence Rate ◽  
Cystic Lesion ◽  
Soft Tissues ◽  
Clinical History ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Clinical Behavior ◽  
Clinical Appearance ◽  
Odontogenic Origin ◽  
Aggressive Clinical Behavior

The Odontogenic keratocyst (OKC) is a developmental, non – inflammatory chronic cystic lesion, on radiograph it may be unilocular or multi locular OKC is a cyst of odontogenic origin, usually asymptomatic with an aggressive clinical behavior including a high recurrence rate and tendency to invade bone and adjacent soft tissues. Diagnosis is based on the clinical history, clinical appearance, and radiographs and histology. A case of odontogenic keratocyst involving the ramus of the mandible is presented in this article emphasizing on the characteristics and various features of OKC.

scholarly journals Immunohistochemical expression of ki-67 in odontogenic keratocyst: Evidence of aggressive behavior.

2020 ◽  
Vol 27 (01) ◽  
pp. 74-79
Author(s):  
Rabiya Saif ◽  
Hafiz Majid Jehangir ◽  
Abdul Hannan Nagi ◽  
Nadia Naseem ◽  
Zainab Rizvi ◽  
...  
Keyword(s):  
Aggressive Behavior ◽  
Descriptive Study ◽  
World Health ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Odontogenic Cysts ◽  
P Value ◽  
Proliferative Potential ◽  
Nuclear Staining ◽  
Ki 67

The odontogenic keratocyst (OKC) well-known for its aggressiveness and high recurrence rate, comprises approximately 11% of all jaw cysts. Due to its aggressive behavior it was placed into category of tumour in 2005 by the World Health Organization (WHO). Objectives: The purpose of this study was to determine the Ki-67 expression in Odontogenic Keratocysts to predict its proliferative potential. Study Design: Descriptive study. Setting: Department of Morbid Anatomy and Histopathology, UHS. Periods: June 2014- June 2018. Material & Methods: This is a descriptive study comprising of 39 cases of odontogenic cysts. These surgically removed samples were processed at University of Health Sciences (UHS) laboratory. Routine staining with Hematoxylin & Eosin stain along with immunohistochemistry (IHC) with Ki-67 antibody was performed. Immunohisto chemical scoring was done on the basis of percentage of the nuclear staining of Ki-67. Data was entered into SPSS 22 and descriptive statistics were measured in the form of percentage and frequency. Quantitative variables such as age of patient, size of the cyst, and Ki-67 score were also measured. P value <0.05 was taken as significant. Results: The mean age of the patients was 25.08 ±14.5 years. Significant association was observed between histological variables with odontogenic keratocyst such as parakeratinized epithelial lining (p = 0.00), epithelial hyperplasia both typical and atypical (p = 0.02) and focal spongiosis (p = 0.04). Foci having epithelial atypia demonstrated stronger staining intensity compared to adjacent normal epithelium. However, no significant association was observed between the histological variables and Ki-67 expression. Conclusion: OKC expressed low Ki-67 expression in most of the cases, however, foci of strong expression were also observed in few cases.

scholarly journals An analysis of the prevalence of peripheral giant cell granuloma and pyogenic granuloma in relation to a dental implant

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nieves Román-Quesada ◽  
Beatriz González-Navarro ◽  
Keila Izquierdo-Gómez ◽  
Enric Jané-Salas ◽  
Antonio Marí-Roig ◽  
...  
Keyword(s):  
Giant Cell ◽  
Dental Implants ◽  
Recurrence Rate ◽  
Pyogenic Granuloma ◽  
High Recurrence Rate ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Oral Implants ◽  
Time Restrictions ◽  
Peripheral Giant Cell Granuloma

Abstract Background The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. It’s important to know the characteristics present in these lesions and possible effects on the prognosis of dental implants. Methods An electronic search without time restrictions was done in the databases: PubMed/Medline. With the keywords "Granuloma" OR "Granuloma, Giant Cell" OR "peripheral giant cell" OR "Granuloma, Pyogenic” AND "Dental implants" OR "Oral implants”. Results After applying the inclusion and exclusion criteria, a total of 20 articles were included, which reported 32 lesions (10 pyogenic granulomas, 21 peripheral giant cell granulomas and one peripheral giant cell granuloma combined with peripheral ossifying fibroma, all associated with implants). According to our review, these lesions are more frequent in males and in the posterior region of the mandible. Both excision and curettage of the lesion, compared to only excision, presented similar recurrences (40%). Explantation of the implant was performed in 41% of cases without additional recurrences. The results are not statistically significant when comparing one lesion to the other in terms of explantation (p = 0.97), recurrence (p = 0.57) or bone loss (p = 0.67). Conclusions The main therapeutic approach is tissue excision. The lesions show a high recurrence rate (34.4%), which often requires explantation of the associated implant. This recurrence rate is not affected by curettage after excision.

scholarly journals Maxillary Odontogenic Keratocyst Masquerading a Periapical Cyst

2018 ◽  
Vol 2 (6) ◽  
pp. 133-137
Author(s):  
Jayaprasad Anekar ◽  
Krishna Santhosh Kumar ◽  
Deepika Nappalli ◽  
Ivin Elsa John
Keyword(s):  
Computed Tomography ◽  
Treatment Planning ◽  
Recurrence Rate ◽  
Aggressive Behaviour ◽  
Odontogenic Cyst ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Keratocystic Odontogenic Tumor ◽  
Advanced Imaging ◽  
Periapical Cyst

Odontogenic keratocysts previously termed, as keratocystic odontogenic tumor is a developmental odontogenic cyst. It is one of the most commonly occurring odontogenic cyst and is characterized by its aggressive behaviour, high recurrence rate and association with syndromes. A case of odontogenic keratocyst occurring in the maxillary anterior region is described here with emphasis on the importance of advanced imaging modalities like computed tomography in the diagnosis and treatment planning.

scholarly journals 14-Year evolution odontogenic keratocyst: Case report

2021 ◽  
Vol 62 (1) ◽  
Author(s):  
Cintia Milani ◽  
◽  
Camyla Mauricio ◽  
Luciano Francio ◽  
Natanael Mattos ◽  
...  
Keyword(s):  
Case Report ◽  
Recurrence Rate ◽  
Bone Destruction ◽  
Good Alternative ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Standard Protocol ◽  
Recurrence Rates ◽  
Panoramic Radiographs ◽  
Carnoy’S Solution

Odontogenic keratocyst is a developmental odontogenic cyst that is usually diagnosed in routine radiographs in the early stages. This fact increases the dentist’s responsibility for its diagnosis, and the professional should pay attention to all maxillomandibular complex and not only to the teeth. There is no standard protocol for the treatment of odontogenic keratocyst. However, surgical resection is recommended because of its high recurrence rate, especially in those cases with extensive bone destruction. The enucleation followed by Carnoy’s solution application has been shown to be a good alternative to resection and pointed out as the conservative method associated with the lowest recurrence rates in the treatment of odontogenic keratocyst. This study aimed to report a case of an extensive odontogenic keratocyst with more than 14 years of evolution that had not been diagnosed in three previous different panoramic radiographs and was treated with enucleation and application of Carnoy’s solution.

scholarly journals Treatment Modalities of Odontogenic Keratocyst of Maxilla and Mandible: Our Experience

2015 ◽  
Vol 6 (4) ◽  
pp. 208-212 ◽  
Author(s):  
Parveen Akhter Lone ◽  
Mohan Singh ◽  
Harpreet Singh Johar
Keyword(s):  
Recurrence Rate ◽  
Maxillofacial Surgery ◽  
Surgical Excision ◽  
Odontogenic Keratocyst ◽  
Treatment Modalities ◽  
High Recurrence Rate ◽  
Oral And Maxillofacial Surgery ◽  
Anterior Maxilla ◽  
Radiographic Appearance ◽  
Maxilla And Mandible

ABSTRACT Background Odontogenic keratocyst (OKC) is known for its most aggressive behavior, high recurrence rate and is most common odontogenic cyst of the jaws. After completion of odontogenesis, some remnants of dental epithelium remain in oral cavity and variety of cysts and tumor can develop from this odontogenic epithelium the most common being odontogenic keratocyst. The most common site of occurrence of OKC reported is mandibular body and ramus region. Objectives The aim of this study is to report the other frequent site of occurrence, different size of OKC in mandible and maxilla and different treatment modalities depending on size, age, and extent of the lesion. Materials and methods Ten patients were selected among the patients referred to the department of oral and maxillofacial surgery with cystic lesions on mandible and maxilla. After making diagnosis treatment planning was done depending upon the age, radiographic appearance and size of the lesion. Results Odontogenic keratocyst was found more in males than females, was found more in mandible than maxilla. Majority of the cases were in mandible angle ramus region followed by anterior maxilla. Seventy-six percent cases were multilocular radiolucencies, whereas 24% unilocular. Multilocular radiolucencies were treated by wide surgical excision, hemimandibulectomy, whereas unilocular radiolucencies were treated by enucleation. Conclusion It is concluded that treatment of OKC depends upon age, radiographic and clinical extent of lesion, unilocular or multilocular appearance, presence of daughter cysts, recurrence rate. How to cite this article Lone PA, Singh M, Johar HS. Treatment Modalities of Odontogenic Keratocyst of Maxilla and Mandible: Our Experience. World J Dent 2015;6(4):208-212.

A complex case of a granulosa cell tumour

2021 ◽  
Vol 14 (12) ◽  
pp. e242224
Author(s):  
Theresa Agius ◽  
Michaela Gatt ◽  
Dylan Falzon ◽  
Darko Babic
Keyword(s):  
Granulosa Cell ◽  
Recurrence Rate ◽  
Cell Tumour ◽  
Complex Case ◽  
High Recurrence Rate ◽  
Not Given ◽  
Granulosa Cell Tumour ◽  
Complete Excision ◽  
Histologic Appearance

This is a case of a 73-year-old woman who first presented in 2020 with a fullness in her abdomen. After several thorough investigations and unforeseen complications, the fullness was diagnosed as a granulosa cell tumour. In 2003, she had been diagnosed with a granulosa cell tumour of the ovary. Complete excision was performed, however she was not given a follow-up appointment after the procedure. This case highlights the importance of frequent follow-up of these tumours, the high recurrence rate, the severe complications which may result and the awareness of possible variations in this tumour’s histologic appearance.

scholarly journals A clinicopathological study and management of odontogenic keratocyst

2019 ◽  
Vol 9 (1) ◽  
pp. 8-15
Author(s):  
Mohammad Asifur Rahman ◽  
Tarin Rahman ◽  
Ismat Ara Haider
Keyword(s):  
Conservative Treatment ◽  
Recurrence Rate ◽  
Surgical Resection ◽  
Treatment Options ◽  
Anatomical Structure ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Odontogenic Cysts ◽  
Odontogenic Keratocysts ◽  
Surgical Methods

Odontogenic Keratocyst is an aggressive odontogenic cyst with a high recurrence rate. After radicular and follicular cysts, odontogenic keratocysts are the third most common cyst of the jaws and approximately 12-14% of all odontogenic cysts. It has been retermed to Keratocystic odontogenic tumour (KCOT) as it better reflects its neoplastic nature but recently it has been re classified and retermed into the cystic category. Various surgical methods have been proposed but comparatively, conservative treatment options such as Dredging methods might be the treatment of choice due to preservation of anatomical structure. Objective: The aim of this study was to analyse the clinical, radiological and histopathological characteristics of Odontogenic Keratocyst and provide a proper management system affected by this type of lesions. Materials and methods: The prospective study was performed in Dhaka Dental College and Hospital from a period of January 2014 to January 2018. A total number of 75 patients were selected for this study based on clinical, radiological and histopathological confirmation of odontogenic keratocysts. The treatment options were enucleation, enucleation with curettage, enucleation with peripheral ostectomy, Dredging method and surgical resection. After treatment patients were followed up 1months, 3 months and 6 months in every year at least for 5 years. Results: Among 75 patient of odontogenic keratocyst; the mean age was 27.69±13.35 and age range was 11 to 66 years. Male were 53(71%) and 22 (29%) were female patients. 53 (70.67%) cases were found in the mandible, 15(20%) cases in the maxilla and in 7(9.33%) cases were involved in both maxilla and mandible; mandibular posterior region was the most specific region involved 37(69.81%).The most common clinical features revealed pain and swelling. Radiologically, 70.66% unilocular, 96% well defined and 94.66% radiolucent area were prominent. Bone expansion 37.38%, root resorption 30.00% and 36% were associated with an impacted tooth. Regarding treatment options enucleation with curatage 12%, enucleation, curettage & peripheral ostectomy 29.33%, Dredging 52% and surgical resection 6.6% was done. Recurrence occurred in 18 patients with recurrence rate of 24%. Conclusion: Odontogenic keratocyst is an aggressive cyst, male predominant, posterior mandible is the commonest site and well defined unilocular radiolucency are commonest radiological feature. Radical treatment options such as resection reduced the recurrences of the tumour but higher morbidity and jaw deformity. Comparatively, conservative treatment options such as Dredging methods might be the treatment of choice due to preservation of anatomical structure. A long term follow up is paramount importance for the research and understanding the clinical pattern, behavior, treatment and recurrence of the lesion. Update Dent. Coll. j: 2019; 9 (1): 8-15

scholarly journals Management of Recurrence of Ameloblastoma and Odontogenic Keratocyst: A Cross-Sectional Study

2020 ◽  
pp. 233-245
Author(s):  
Onur Yilmaz ◽  
Zeynep Sagnak Yilmaz ◽  
Emre Balaban ◽  
Celal Candirli
Keyword(s):  
Recurrence Rate ◽  
Cross Sectional Study ◽  
Segmental Resection ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Significant Relation ◽  
Cross Sectional ◽  
Safety Margins ◽  
The Mean

Objectives: Odontogenic keratocyst (OKC) and ameloblastoma are slowly growing and locally invasive tumors with high recurrence rate. The aim of this study was to investigate the clinicopathologic features of recurrent ameloblastoma and OKC cases, and evaluate outcomes of our treatments in terms of recurrence. Material and Methods: A total of 23 patients with confirmed recurrent ameloblastoma or OKC and treated in our clinic within eleven years period were reviewed retrospectively. Results: Eleven recurrent OKC cases and twelve recurrent ameloblastoma cases were included. Most recurrences occurred within five years after the initial treatment (69.6%). Enucleation had the highest recurrence rate among the first treatments (18/23). All recurrences were located in the mandible, with one exception (22/23). All recurrent OKCs were multilocular. Different histopathologic subtypes of ameloblastoma were seen in our study, follicular ameloblastoma was the most common (8/12). The mean diameter of the lesions was 4.3 cm (ranging from 2 cm to 7 cm). Statically significant relation was found between location and diameter of lesion and year of recurrence onset (p=0.004; p=0.026). We performed radical treatments in these cases (ten patients underwent marginal resections, and thirteen patients underwent segmental resection), and no recurrence was observed during the follow-up period. Conclusion: Previous inadequate surgical procedures were the most important cause of recurrence. Marginal or segmental resection with safety margins is the best method to treat recurrences of OKC or ameloblastoma cases.

14-Year evolution odontogenic keratocyst: Case report

2021 ◽  
Vol 62 (1) ◽  
Author(s):  
Cintia Milani ◽  
◽  
Camyla Mauricio ◽  
Luciano Francio, ◽  
Natanael Mattos ◽  
...  
Keyword(s):  
Case Report ◽  
Recurrence Rate ◽  
Bone Destruction ◽  
Good Alternative ◽  
Odontogenic Keratocyst ◽  
High Recurrence Rate ◽  
Standard Protocol ◽  
Recurrence Rates ◽  
Panoramic Radiographs ◽  
Carnoy’S Solution

Odontogenic keratocyst is a developmental odontogenic cyst that is usually diagnosed in routine radiographs in the early stages. This fact increases the dentist’s responsibility for its diagnosis, and the professional should pay attention to all maxillomandibular complex and not only to the teeth. There is no standard protocol for the treatment of odontogenic keratocyst. However, surgical resection is recommended because of its high recurrence rate, especially in those cases with extensive bone destruction. The enucleation followed by Carnoy’s solution application has been shown to be a good alternative to resection and pointed out as the conservative method associated with the lowest recurrence rates in the treatment of odontogenic keratocyst. This study aimed to report a case of an extensive odontogenic keratocyst with more than 14 years of evolution that had not been diagnosed in three previous different panoramic radiographs and was treated with enucleation and application of Carnoy’s solution.

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