Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals: a community-based study

Abstract Background The mid-upper arm circumference (MUAC) is a proxy for subcutaneous fat in the upper body and is a reliable screening measure for identifying individuals with abnormal local fat distribution. The purpose of this study was to evaluate the association between MUAC and metabolic syndrome (MetS) in middle-aged and elderly individuals. Methods We measured the MUAC in a cross-sectional sample with a total of 9787 subjects aged 40 years and older. The measurement of MUAC is performed on the right arm using a non‐elastic tape held midway between the acromion and the olecranon processes in duplicate, with the arm hanging loosely at the side of the body. The MetS was defined according to the Joint Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention. Results MUAC was positively correlated with waist circumference (r=0.437, P<0.001), BMI (r=0.334, P<0.001), fasting insulin(r=0.348, P<0.001), HOMA-IR (r=0.134, P< 0.001), triglycerides (r=0.138, P<0.001), SBP (r=0.124, P< 0.001), and DBP(r= 0.123, P<0.001), and inversely correlated with adiponectin (r=-0.147, P < 0.001) and HDL-cholesterol (r=-0.176, P<0.001) after adjusting for age and gender. Compared with the lowest quartile group, the odds ratios were substantially higher for MetS (OR 1.77; 95% CI 1.51-2.09, P for trend<0.001) in the highest MUAC quartile group after adjustment for potential cofounder. Conclusion Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals .

Download Full-text

Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals: a community-based study

10.21203/rs.2.16072/v5 ◽

2020 ◽

Author(s):

Jie Shi ◽

Zhen Yang ◽

Yixin Niu ◽

Weiwei Zhang ◽

Xiaoyong Li ◽

...

Keyword(s):

Metabolic Syndrome ◽

Subcutaneous Fat ◽

International Diabetes Federation ◽

The Body ◽

Middle Aged ◽

Upper Arm ◽

Elderly Individuals ◽

Arm Circumference ◽

Quartile Group ◽

Mid Upper Arm Circumference

Abstract Background The mid-upper arm circumference (MUAC) is a proxy for subcutaneous fat in the upper body and is a reliable screening measure for identifying individuals with abnormal regional fat distribution. The purpose of this study was to evaluate the association between MUAC and metabolic syndrome (MetS) in middle-aged and elderly individuals. Methods We measured the MUAC in a cross-sectional sample with a total of 9787 subjects aged 40 years and older. The measurement of MUAC is performed on the right arm using a non‐elastic tape held midway between the acromion and the olecranon processes in duplicate, with the arm hanging loosely at the side of the body. The MetS was defined according to the Joint Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention. Results MUAC was positively correlated with waist circumference (r=0.437, P<0.001), BMI (r=0.334, P<0.001), fasting insulin (r=0.348, P<0.001), HOMA-IR (r=0.134, P< 0.001), triglycerides (r=0.138, P<0.001), SBP (r=0.124, P< 0.001), and DBP (r= 0.123, P<0.001), and inversely correlated with adiponectin (r=-0.147, P < 0.001) and HDL-cholesterol (r=-0.176, P<0.001) after adjusting for age and gender. Compared with the lowest quartile group, the odds ratios were substantially higher for MetS (OR 1.77; 95% CI 1.51-2.09, P for trend<0.001) in the highest MUAC quartile group after adjustment for potential cofounder. Conclusion Large mid-upper arm circumference is significantly associated with metabolic syndrome in middle-aged and elderly individuals .

Download Full-text

Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals: a community-based study

10.21203/rs.2.16072/v3 ◽

2020 ◽

Author(s):

Jie Shi ◽

Zhen Yang ◽

Yixin Niu ◽

Weiwei Zhang ◽

Xiaoyong Li ◽

...

Keyword(s):

Metabolic Syndrome ◽

Subcutaneous Fat ◽

International Diabetes Federation ◽

The Body ◽

Middle Aged ◽

Upper Arm ◽

Elderly Individuals ◽

Arm Circumference ◽

Quartile Group ◽

Mid Upper Arm Circumference

Abstract Background: The mid-upper arm circumference (MUAC) is a proxy for subcutaneous fat in the upper body and is a reliable screening measure for identifying individuals with abnormal local fat distribution. The purpose of this study was to evaluate the association between MUAC and metabolic syndrome (MetS) in middle-aged and elderly individuals.Methods: We measured the MUAC in a cross-sectional sample with a total of 9787 subjects aged 40 years and older. The measurement of MUAC is performed on the right arm using a non‐elastic tape held midway between the acromion and the olecranon processes in duplicate, with the arm hanging loosely at the side of the body. The MetS was defined according to the Joint Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention.Results: MUAC was positively correlated with waist circumference (r=0.437, P<0.001), BMI (r=0.334, P<0.001), fasting insulin (r=0.348, P<0.001), HOMA-IR (r=0.134, P< 0.001), triglycerides (r=0.138, P<0.001), SBP (r=0.124, P< 0.001), and DBP (r= 0.123, P<0.001), and inversely correlated with adiponectin (r=-0.147, P < 0.001) and HDL-cholesterol (r=-0.176, P<0.001) after adjusting for age and gender. Compared with the lowest quartile group, the odds ratios were substantially higher for MetS (OR 1.77; 95% CI 1.51-2.09, P for trend<0.001) in the highest MUAC quartile group after adjustment for potential cofounder.Conclusion: Large mid-upper arm circumference is significantly associated with metabolic syndrome in middle-aged and elderly individuals.

Download Full-text

Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals: a community-based study

10.21203/rs.2.16072/v4 ◽

2020 ◽

Author(s):

Jie Shi ◽

Zhen Yang ◽

Yixin Niu ◽

Weiwei Zhang ◽

Xiaoyong Li ◽

...

Keyword(s):

Metabolic Syndrome ◽

Subcutaneous Fat ◽

International Diabetes Federation ◽

The Body ◽

Middle Aged ◽

Upper Arm ◽

Elderly Individuals ◽

Arm Circumference ◽

Quartile Group ◽

Mid Upper Arm Circumference

Abstract Background The mid-upper arm circumference (MUAC) is a proxy for subcutaneous fat in the upper body and is a reliable screening measure for identifying individuals with abnormal regional fat distribution. The purpose of this study was to evaluate the association between MUAC and metabolic syndrome (MetS) in middle-aged and elderly individuals.Methods We measured the MUAC in a cross-sectional sample with a total of 9787 subjects aged 40 years and older. The measurement of MUAC is performed on the right arm using a non‐elastic tape held midway between the acromion and the olecranon processes in duplicate, with the arm hanging loosely at the side of the body. The MetS was defined according to the Joint Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention.Results MUAC was positively correlated with waist circumference (r=0.437, P<0.001), BMI (r=0.334, P<0.001), fasting insulin (r=0.348, P<0.001), HOMA-IR (r=0.134, P< 0.001), triglycerides (r=0.138, P<0.001), SBP (r=0.124, P< 0.001), and DBP (r= 0.123, P<0.001), and inversely correlated with adiponectin (r=-0.147, P < 0.001) and HDL-cholesterol (r=-0.176, P<0.001) after adjusting for age and gender. Compared with the lowest quartile group, the odds ratios were substantially higher for MetS (OR 1.77; 95% CI 1.51-2.09, P for trend<0.001) in the highest MUAC quartile group after adjustment for potential cofounder.Conclusion Large mid-upper arm circumference is significantly associated with metabolic syndrome in middle-aged and elderly individuals.

Download Full-text

Mid-upper arm circumference, central obesity and metabolic syndrome in middle-aged and elderly Chinese: the REACTION study

10.21203/rs.2.16072/v1 ◽

2019 ◽

Author(s):

Jie Shi ◽

Zhen Yang ◽

Yixin Niu ◽

Weiwei Zhang ◽

Xiaoyong Li ◽

...

Keyword(s):

Metabolic Syndrome ◽

Confidence Interval ◽

Odds Ratio ◽

Central Obesity ◽

The Body ◽

Metabolic Phenotype ◽

Middle Aged ◽

Upper Arm ◽

Arm Circumference ◽

Mid Upper Arm Circumference

Abstract Background The mid-upper arm circumference (MUAC) is a proxy for upper body subcutaneous fat and a reliable screening measure for identification of individuals with abnormal local fat distribution. The purpose of present study was to evaluate the association between MUAC and metabolic syndrome (MetS) as well as other metabolic phenotype in the middle-aged and elderly population. Methods We measured the MUAC in a cross-sectional sample with a total of 9787 subjects aged 40 years and older in Shanghai, China. The measurement of MUAC is performed on the right arm using a non‐elastic tape held midway between the acromion and the olecranon processes in duplicate, with arm hanging loosely at the side of the body. The MetS was defined according to the Joint Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention. The association of MUAC with MetS was tested in logistic regression analyses and reported as odds ratio (OR) with 95% confidence interval (CI). Results T he prevalence of MetS, overweight, and central obesity raised sharply from the smaller MUAC groups to the larger MUAC groups both in men and women. MUAC was positively correlated with waist circumference, BMI, fasting insulin, HOMA-IR, triglycerides, systolic and diastolic blood pressure, and inversely correlated with adiponectin and HDL-cholesterol after adjusting for age and gender. As the MetS components accumulated, the MUAC increased concomitantly. The risk of MetS in the highest MUAC quartile was significant higher (odds ratio 1.77; 95% confidence interval 1.51-2.09) than the lowest quartile after adjustment of potential confounders. Conclusion Our results indicated that large MUAC is an independent risk factor of MetS in Chinese individuals.

Download Full-text

Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals: a community-based study

BMC Endocrine Disorders ◽

10.1186/s12902-020-00559-8 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Jie Shi ◽

Zhen Yang ◽

Yixin Niu ◽

Weiwei Zhang ◽

Xiaoyong Li ◽

...

Keyword(s):

Metabolic Syndrome ◽

Middle Aged ◽

Community Based ◽

Upper Arm ◽

Elderly Individuals ◽

Arm Circumference ◽

Mid Upper Arm Circumference

Download Full-text

Effect of Supportive Intravenous Hyperalimentation on the Nutritional Status of Cancer Patients

Tumori Journal ◽

10.1177/030089168006600213 ◽

1980 ◽

Vol 66 (2) ◽

pp. 241-254 ◽

Cited By ~ 2

Author(s):

Federico Bozzetti ◽

Giovanni Terno ◽

Fabio Baticci ◽

Maria Grazia Bonalumi ◽

Adriana Scotti ◽

...

Keyword(s):

Clinical Trials ◽

Nutritional Status ◽

Cancer Patients ◽

The Body ◽

Skin Tests ◽

Upper Arm ◽

Intravenous Hyperalimentation ◽

Lymphocyte Blastogenesis ◽

Arm Circumference ◽

Mid Upper Arm Circumference

The effect of intravenous hyperalimentation on the nutritional status of 84 cancer patients treated at the Istituto Nazionale Tumori, Milan, has been evaluated. The body weight increased in 78 % of patients, mid upper arm circumference in 93 %, triceps skinfold in 73 %, mid upper arm-muscle circumference in 73 %, creatinine/height index in 30 %, serum albumin in 32 %, transferrin in 35 %, total peripheral lymphocytes in 38 %. Lymphocyte blastogenesis increased in 74 % of the patients examined and skin tests were converted from negative to positive in about 20 % of patients. In addition 8 out of 18 patients responsive to IVH benefited from chemotherapy and/or radiotherapy indicating that the nutritional repletion of the host did not significantly affect the growth of the tumor. These findings support the opinion that neoplastic cachexia may depend partially on malnutrition and can be often reversed by IVH. Moreover, IVH might have an adjunctive role as potentiator of chemotherapy which however must be confirmed by clinical trials.

Download Full-text

Mid-upper arm circumference as a substitute of the body mass index for assessment of nutritional status among adult and adolescent females: learning from an impoverished Indian state

Public Health ◽

10.1016/j.puhe.2019.09.010 ◽

2020 ◽

Vol 179 ◽

pp. 68-75 ◽

Cited By ~ 1

Author(s):

A. Das ◽

G. Saimala ◽

N. Reddy ◽

P. Mishra ◽

R. Giri ◽

...

Keyword(s):

Body Mass Index ◽

Nutritional Status ◽

Body Mass ◽

Adolescent Females ◽

The Body ◽

Upper Arm ◽

Arm Circumference ◽

Indian State ◽

Mid Upper Arm Circumference

Download Full-text

Effects of a Combined Exercise Program on the Body Composition, Health-related Physical Fitness, and Metabolic Syndrome Risk Factor in Middle-aged Women

The Official Journal of the Korean Academy of Kinesiology ◽

10.15758/jkak.2013.15.3.91 ◽

2013 ◽

Vol 15 (3) ◽

pp. 91-100

Author(s):

SuIll Oh ◽

유민주 ◽

황예선

Keyword(s):

Metabolic Syndrome ◽

Body Composition ◽

Risk Factor ◽

Physical Fitness ◽

Exercise Program ◽

The Body ◽

Middle Aged ◽

Combined Exercise ◽

Health Related ◽

Metabolic Syndrome Risk Factor

Download Full-text

Mid upper arm circumference as an alternative measure to assess the nutritional status of adolescents: a study in India based on NFHS-4 data

Journal of Biosocial Science ◽

10.1017/s0021932021000298 ◽

2021 ◽

pp. 1-12

Author(s):

Aparna Roy ◽

T. V. Sekher

Keyword(s):

Nutritional Status ◽

Sensitivity And Specificity ◽

Measurement Data ◽

Anthropometric Measurement ◽

Alternative Measure ◽

Upper Arm ◽

Male Adolescents ◽

Arm Circumference ◽

Mid Upper Arm Circumference ◽

The Relationship

Abstract Use of body mass index (BMI) to assess the nutritional status of adolescents requires many resources, especially for country-level assessment. This study aimed to determine the relationship between BMI and mid upper arm circumference (MUAC) among adolescent males and females in India and to examine whether MUAC effectively represents the nutritional status of adolescents. The study utilized anthropometric measurement data collected by India’s National Family Health Survey-4 (2015–16). The weighted sample for analysis included 91,315 female and 14,893 male adolescents. The BMI and MUAC measurements showed a positive correlation in both female and male adolescents. Using BMI-for-age Z-score classifications, 12.7% of the adolescents were undernourished. Using MUAC (in cm) as per NACS (Nutrition Assessment, Counselling, and Support) guidelines and Mramba et al. (2017) classified 22.9% and 3.7% of the adolescents as undernourished respectively. Finally, using the MUAC-for-age Z-score classification, 98.4% of adolescents were determined to be normal and 1.7% undernourished. Sensitivity and specificity tests of the MUAC cut-offs, in comparison with BMI cut-offs, showed that all three MUAC cut-off classifications had high specificity (NACS cut-off: 81.3%; Mramba et al. cut-off (cm): 97.7%; Mramba et al. cut-off (Z-score): 99.1%). The NACS cut-off had moderately high sensitivity (52.2%) but the Mramba et al. cut-offs had low sensitivity (13.3% for the centimetre cut-off and 6.6% for the Z-score cut-off). Sensitivity and specificity tests proved the relationship between BMI and MUAC, and that MUAC represents adolescent nutritional status with considerable efficiency. With further research, it may be established that MUAC is a better and promising measure of adolescent nutrition, having the advantage of needing fewer resources for data collection. The MUAC has the potential to offer a simple and low-resource alternative to BMI to assess nutritional status among adolescents in poor countries.

Download Full-text