Innate Immune Surveillance in the Central Nervous System Following Legionella pneumophila Infection

2018 ◽  
Vol 16 (10) ◽  
pp. 1080-1089 ◽  
Author(s):  
Pasqualina Lagana ◽  
Luca Soraci ◽  
Maria Elsa Gambuzza ◽  
Giuseppe Mancuso ◽  
Santi Antonino Delia
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Legionella Pneumophila ◽  
Immune Surveillance ◽  
Innate Immune ◽  
The Central Nervous System

scholarly journals Immune surveillance in the central nervous system

2012 ◽  
Vol 15 (8) ◽  
pp. 1096-1101 ◽  
Author(s):  
Shalina S Ousman ◽  
Paul Kubes
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Immune Surveillance ◽  
The Central Nervous System

Immunology of Multiple Sclerosis

2016 ◽  
Author(s):  
Laura Piccio ◽  
Anne H. Cross
Keyword(s):  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Monoclonal Antibodies ◽  
B Lymphocytes ◽  
Autoimmune Disorder ◽  
Innate Immune ◽  
Immune Systems ◽  
The Central Nervous System ◽  
Multiple Sclerosis Treatment

Multiple sclerosis (MS) is considered to be an autoimmune disease of the central nervous system that targets myelin but affects both white matter and gray matter. Multiple sclerosis is thought to be mediated by cells of the adaptive and innate immune systems. CD4+ T lymphocytes of the Th1 and Th17 subtypes are believed to be critical for the initiation of multiple sclerosis. Treatment with monoclonal antibodies that deplete B lymphocytes has proven that B cells are critical to relapse development in multiple sclerosis. While immunopathophysiology is clearly important in MS, whether multiple sclerosis is truly an autoimmune disorder and the target or targets of the autoimmunity remain unknown.

scholarly journals Compartmentalization of innate immune responses in the central nervous system during cryptococcal meningitis/HIV coinfection

AIDS ◽  
2014 ◽  
Vol 28 (5) ◽  
pp. 657-666 ◽  
Author(s):  
Vivek Naranbhai ◽  
Christina C. Chang ◽  
Raveshni Durgiah ◽  
Saleha Omarjee ◽  
Andrew Lim ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Immune Responses ◽  
Cryptococcal Meningitis ◽  
Innate Immune ◽  
Innate Immune Responses ◽  
Hiv Coinfection ◽  
The Central Nervous System
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