scholarly journals Manfaat aloe vera sebagai terapi topikal luka bakar

2020 ◽  
Vol 2 (1) ◽  
pp. 141-146
Author(s):  
Helen Kusuma Wardani

Aloe vera is an herbal plant that has been used extensively for centuries as a natural medicine. Aloe vera therapy activities can be used to treat skin lesions, such as burns. The gel has healing, analgesic, and anti-inflammatory activity, besides being a powerful moisturizing and protective skin agent. The speed of healing in the aloe vera group is better than the conventional group. Effects produced by aloe vera gel with reference to wound contraction, wound closure, decrease in wound surface area, tissue regeneration at the wound site. Aloe vera contains important nutrients such as vitamins A, C and E, which act as antioxidants, minerals (calcium, copper, magnesium, potassium, and zinc), enzymes, glycoproteins, amino acids, carbohydrate constituents, such as polysaccharides and salicylic acids

2013 ◽  
Vol 683 ◽  
pp. 141-144 ◽  
Author(s):  
Rúben Pereira ◽  
Ausenda Mendes ◽  
Paulo J. Bártolo

The treatment of skin lesions is a costly and complex process, for which different strategies are currently available. In this study, we investigated the properties of novel films composed of alginate and aloe vera gel for application as wound dressing material. The films combine the occlusive and haemostatic properties of calcium alginate gels with the therapeutic properties of aloe vera. We expect that these films may improve the healing process through the release of aloe vera compounds directly into the wound bed and could be an alternative to the administration of synthetic drugs to infected wounds. The films exhibited high transparency in both dry and wet state, as well as adequate mechanical properties for skin use. The results indicated that the films present great potential to be explored as wound dressing material.


2020 ◽  
Vol 4 (2) ◽  
pp. 132
Author(s):  
Nur Hasanah ◽  
Fenita Purnama Sari Indah ◽  
Dede Anggraeni ◽  
Nurwulan Adi Ismaya ◽  
Lela Kania Rahsa Puji

Aloe vera plant has considerable potential as a raw material for natural medicine. In this aloe vera contains various active substances that can cure various diseases. Aloe vera gel is formulated by mixing the results of aloe vera extract with a suiTabel base. A good gel preparation can be obtained by formulating several types of gelling agents, but the most important thing to note is the selection of Gelling agents. Physical stability tests need to be carried out to ensure the quality, safety and benefits of the gel meet the expected specifications and are sTabel during storage. The purpose of this study is to describe and compare the formulations and physical satellites of aloe vera extract gel preparations with different concentrations of bases on each formulation from various literature. This research uses the literature study research method by collecting various sources of literature from 10 research journals. The results of this review explain that all bases used in each formulation with a predetermined concentration value and with a mixture of other ingredients that have been determined produce good physical stability of each formulation.Keywords:Aloe vera formulation Physical stability tests  ABSTRAKTanaman lidah buaya mempunyai potensi yang cukup besar sebagai bahan baku obat alami. Dalam lidah buaya ini mengandung berbagai zat aktif yang dapat menyembuhkan berbagai penyakit. Gel lidah buaya diformulasikan dengan mencampur hasil ekstrak lidah buaya dengan basis yang sesuai. Sediaan gel yang baik dapat diperoleh dengan cara memformulasikan beberapa jenis bahan pembentuk gel, namun yang paling penting untuk diperhatikan adalah pemilihan gelling agent. Uji stabilitas fisik perlu dilakukan untuk memastikan kualitas,keamanan dan manfaat gel memenuhi spesifikasi yang diharapkan serta stabil selama penyimpanan. Tujuan penelitian ini memaparkan dan membandingkan formulasi dan uji satbilitas fisik sediaan gel ekstrak lidah buaya dengan perbedaan konsentrasi basis pada setiap formulasi dari berbagai literatur. Penelitian ini menggunakan metode penelitian studi literatur dengan mengumpulkan berbagi sumber pustaka dari 10 jurnal penelitian. Hasil review ini menjelaskan bahwa semua basis yang digunakan pada setiap formulasi dengan nilai konsentrasi yang sudah ditetapkan dan dengan campuran bahan lainnya yang sudah ditentukan menghasilkan stabilitas fisik masing-masing formulasi dengan baik.Kata Kunci: Lidah buayaFormulasiUji stabilitas fisik


2021 ◽  
Vol 4 (1) ◽  
pp. 46-49
Author(s):  
Bagus Uda Palgunadi ◽  
Asih Rahayu ◽  
Yos Adi Prakoso

Wound is a pathological processes in all living things. Wound includes the overlapping mechanisms. The failure in wound healing causes infection. This study aimed to analyze the efficacy of Aloe vera gel in excisionwound on the rat’s back. This study used 18 male, Sprague Dawley rats, and they were induced excision wound on the back. The rats were separated into 3 groups, K1 = control, K2 = treated with betadin gel, K3 = treated with Aloe vera gel. The therapy was given twice a day for 7 days. The wound measurement was observed in day 3 and 7. The data were analyzed using SPSS. The result showed that Aloe vera gel potentially promote wound healing through the decrease microscopical condition of wound, re-epithelialization, and deposition of collagen better than in group K1 and K2 (p≤0.05). In conclusion, Aloe vera gel promote excision wound healing in Sprague Dawley rats.


Author(s):  
Eman Tharwat Mohamed ◽  
Nawal Ebeid Hanna ◽  
Dalia Salah El-Deen ◽  
Soad Hanna Tadros ◽  
Noha Yehia Ibrahim

2016 ◽  
Vol 13 (3) ◽  
pp. 471-480 ◽  
Author(s):  
Lonette Wallis ◽  
Maides Malan ◽  
Chrisna Gouws ◽  
Dewald Steyn ◽  
Suria Ellis ◽  
...  

2020 ◽  
Vol 10 (2) ◽  
pp. 117-122
Author(s):  
Elizca Pretorius ◽  
Clarissa Willers ◽  
Josias H. Hamman ◽  
Johan D. Steyn

Background: The oral administration route is still the most preferred by patients for drug treatment, but is unfortunately not suitable for all drug compounds. For example, protein and peptide drugs (e.g. insulin) are typically administered via injection seeing as they are unstable in the gastrointestinal luminal environment and have poor membrane permeation properties. To overcome this problem, functional excipients such as drug absorption enhancers can be co-administered. Although Aloe vera gel has the ability to improve the permeation of drugs across the intestinal epithelium, its drug permeation enhancing effect has not been investigated in the different regions of the gastrointestinal tract yet. Objective: The aim of this study was to investigate the insulin permeation enhancing effects of A. vera gel material across excised pig intestinal tissues from different regions of the gastrointestinal tract and to identify the gastrointestinal region where the highest insulin permeation enhancement was achieved. : Insulin transport across excised pig intestinal tissues from the duodenum, proximal jejunum, medial jejunum, distal jejunum, ileum and colon was measured in the absence and presence of A. vera gel (0.5% w/v) using both the Sweetana-Grass diffusion chamber and everted sac techniques. Results: The insulin permeation results obtained from both ex vivo techniques showed varied permeation enhancing effects of A. vera gel as a function of the different regions of the gastrointestinal tract. The colon was identified as the gastrointestinal region where A. vera gel was the most effective in terms of insulin permeation enhancement in the Sweetana-Grass diffusion chamber technique with a Papp value of 5.50 x 10-7 cm.s-1, whereas the ileum was the region where the highest permeation enhancement occurred in the everted sac technique with a Papp value of 5.45 x 10-7 cm.s-1. Conclusion: The gastrointestinal permeation enhancing effects of A. vera gel on insulin is region specific with the highest effect observed in the ileum and colon.


2021 ◽  
Vol 6 ◽  
pp. 100017
Author(s):  
M. Vasudha ◽  
Devaraja Gayathri ◽  
Soundarya S Gurum ◽  
MR Kavya ◽  
HP Nagaswarupa ◽  
...  
Keyword(s):  

Author(s):  
Praveen Kumar Arumugam ◽  
Vamseedharan Muthukumar ◽  
Rahul Bamal

Abstract Fasciotomy is indicated to relieve compartment syndrome caused by electric burns. Many techniques are available to close the fasciotomy wounds including vacuum-assisted closure, skin grafting, and healing by secondary intention. This study assessed the shoelace technique in fasciotomy wound closure in patients with electric burns. The study included 19 fasciotomy wounds that were treated by shoelace technique (Group ST, n = 10 fasciotomy wounds) or by skin grafting/healing by secondary intention (Group C, n = 9 fasciotomy wounds). Data were collected for wound surface area, time to intervention, time to wound closure, rate of decrease in wound surface area after application of shoelace technique and associated complications. The mean time to intervention after fasciotomy was significantly lower in Group ST—7.6 ± 3.8 days as compared to 15.8 ± 5.3 days in Group C (P = .004). The median time to closure was also significantly lower in Group ST—7 days (range 6–10) as compared to Group C—20 days (range 12–48) (P < .001). Primary closure was achieved in 80% cases in the group ST and no complications were recorded. The shoelace technique is an economical, fast, and effective method of fasciotomy wound closure in electric burns, especially in high volume centers and resource-limited areas.


2021 ◽  
Vol 125 ◽  
pp. 108459
Author(s):  
S. Pavithra ◽  
A. Priya ◽  
M. Jayachandran ◽  
T. Vijayakumar ◽  
T. Maiyalagan ◽  
...  

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