scholarly journals Case Report and Highlight Clues on the Diagnosis of Pilomatrical Carcinoma

2021 ◽  
Vol 4 (3) ◽  
pp. 179-183
Author(s):  
Lewkowicz Milagros ◽  
Greco Alejandro ◽  
Lezcano Gabriel ◽  
Cachau Victoria ◽  
Díaz Florencia
Keyword(s):  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Genetic Alterations ◽  
Auricular Cartilage ◽  
Squamous Cells ◽  
Basaloid Cell ◽  
Safety Margins ◽  
Adnexal Tumor ◽  
Accelerated Growth ◽  
Trichilemmal Keratinization

Pilomatrical Carcinoma (PC) is a rare malignant adnexal tumor with matrical differentiation. Its benign counterpart (Pilomatrixoma) is diagnosed much more frequently in daily pathological practice. Both entities share genetic alterations but the malignant counterpart acquires mutations that make it develop an aggressive behavior [1]. We describe a 33-year-old man who presented with a 7 x 6 cm nodular ulcerated lesion in the left ear with markedly accelerated growth in the last month. Incisional biopsy was referred to us with suspicion of squamous cell carcinoma versus pyogenic granuloma. Histologic sections showed ulcerated fragments infiltrated by a basaloid cell proliferation interspersed with groups of “ghost cells”. The neoplastic cells were arranged in irregular sheets with infiltrative borders. Groups of Squamous cells with trichilemmal keratinization and foci of necrosis were also identified. The biopsy was diagnosed as an adnexal neoplasm with pilomatrical differentiation, suggesting its complete resection with safety margins due to the presence of aggressive characteristics. The subsequent study of the excisional biopsy showed similar characteristics to those previously described. Notoriously, focal infiltration of the auricular cartilage was identified, leading us to the undoubted diagnosis of pilomatrical carcinoma.

scholarly journals diode laser for excisional biopsy of pyogenic granuloma: a case series

2017 ◽  
Vol 5 (2) ◽  
pp. 112
Author(s):  
Gaurav Mahajan ◽  
Aditi Gautam
Keyword(s):  
Diode Laser ◽  
Traumatic Injury ◽  
Case Series ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Low Grade ◽  
Giant Cell Granuloma ◽  
Hormonal Factors ◽  
Peripheral Giant Cell Granuloma

Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low- grade local irritation, traumatic injury or hormonal factors. The clinical diagnosis of such lesion can be quite challenging because of its close resemblance to certain malignancies like peripheral giant cell granuloma, kaposi’s sarcoma, non hodgkin’s lymphoma etc. for excisional biopsy, options available are conventional surgical excision, electrocautery or lasers. In this report, we seek to highlight the therapeutic advantages achieved with a soft tissue diode laser in the treatment of pyogenic granuloma.

scholarly journals 128 Rapidly Proliferative Pilomatrixoma On the Eyebrow of A 7-Year-Old Boy – A Case Report

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
M Patel ◽  
M Sinha
Keyword(s):  
Secondary Care ◽  
Age Distribution ◽  
Young Patients ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Sebaceous Cyst ◽  
Careful Clinical Examination ◽  
Hair Matrix ◽  
Previous Trauma ◽  
History Of

Abstract Pilomatrixoma or calcifying epithelioma of Malherbe is a benign tumour originating from pluripotent precursors of hair matrix cells. We present a paediatric patient with a rapidly enlarging eyebrow mass with a differential diagnosis of sebaceous cyst, pyogenic granuloma, or malignancy. A 7-year-old boy presented in primary care with a 0.5cm non-inflammatory nodule on his medial brow present for 2-3 months. History of previous trauma was not elicited and there were no features of bleeding or ulceration. It was then lanced, following diagnosis of an infected sebaceous cyst. Within weeks, the nodule underwent rapid proliferation, enlarging to 2cm in diameter. He was urgently referred to secondary care pending further investigation for possible trauma-induced pyogenic granuloma or malignancy. Upon presentation in secondary care, we observed a protruding erythematous and ulcerated mass, indurated in texture and adherent to overlying skin. The patient was submitted to excisional biopsy with a vertical elliptical approach to minimise distortion of the brow. Small, calcified deposits were observed in the tumour substance. Histologically, basaloid basophilic cells were predominant and mixed with ghost cells and foci of giant multinucleate cells, verifying diagnosis of a pilomatrixoma. Pilomatrixoma exhibits tendency towards mimicry of lesions such as epidermoid, sebaceous, dermoid cyst, pyogenic granuloma or even keratoacanthoma with a pre-operative detection rate as low as 11%. With a bimodal age distribution, arising in the first and sixth decades of life, this case highlights a need for a high degree of suspicion in young patients with careful clinical examination in order to aid diagnosis and prompt appropriate treatment.

scholarly journals A Case of Odontogenic Fistula Misdiagnosed as Cutaneous Ulcer on the Alar-Facial Angle

2020 ◽  
Vol 16 (3) ◽  
pp. 177-181
Author(s):  
Yoon Soo Kim ◽  
Byeong Seok Kim ◽  
Ho Sung Kim ◽  
Seok Kyung In ◽  
Hyung Suk Yi ◽  
...  
Keyword(s):  
Wound Dehiscence ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Skin Lesions ◽  
Sinus Tract ◽  
Epidermal Cyst ◽  
Cutaneous Fistula ◽  
Dental Origin ◽  
Cutaneous Ulcer ◽  
Disease Free

Odontogenic cutaneous fistula of dental origin at the alar-facial groove is rarely reported. As many patients present with only skin lesions without dental problems, it is often confused with a cyst, abscess or pyogenic granuloma. We report the case of a 52-year-old man who presented with a relapsing cutaneous ulcer in the left alar-facial groove area. Ultrasonography findings suggested a ruptured epidermal cyst, and an excisional biopsy was performed. At 10 days after the surgery, wound dehiscence and pus discharge were observed. Computed tomography revealed a sinus tract, and a diagnosis of odontogenic cutaneous fistula was made. After consultation with the dental department, endodontic treatment was performed. During reoperation, a remnant fistula from the left alar-facial groove area to the left upper central incisor was observed, for which fistulectomy was performed. The patient remained disease-free postoperatively. With early accurate diagnosis, patients with odontogenic cutaneous fistula can be protected from unnecessary surgical intervention and ineffective antibiotic therapy.

scholarly journals A Rare Case of Pyogenic Granuloma in the Tooth Extraction Socket

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Yosuke Iijima ◽  
Nami Nakayama ◽  
Leona Kashimata ◽  
Miki Yamada ◽  
Ryutaro Kawano ◽  
...  
Keyword(s):  
Rare Case ◽  
Tooth Extraction ◽  
Dentigerous Cyst ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Histopathological Diagnosis ◽  
Wisdom Tooth ◽  
Complete Excision ◽  
Extraction Socket ◽  
Second Molar

Pyogenic granuloma (PG) refers to a common, acquired, benign, and vascular tumor that arises in tissues such as the skin and mucous membranes. However, it is extremely rare for PG to arise from an empty socket after tooth extraction. Herein, we describe a rare case of PG that arose from the empty extraction socket of the second molar adjacent to a dentigerous cyst of the left mandibular wisdom tooth in a 57-year-old man. The patient’s second molar was extracted during the same procedure in which the wisdom tooth and cyst were removed. Subsequently, at 42 days after surgery, an exophytic mass was found in the socket of the second molar. An excisional biopsy was performed, and the histopathological diagnosis was PG. Since the PG recurred 90 days after the surgery, a complete excision with bone curettage was performed. During the 12 months of follow-up, there has been no recurrence observed. In conclusion, as tooth extraction is a routine dental practice, clinicians should be aware that PGs can also develop from an extraction socket.

scholarly journals Pyogenic granuloma in pregnancy: A study at Liaquat University Hospital.

2020 ◽  
Vol 27 (03) ◽  
pp. 673-676
Author(s):  
Bushra Arain ◽  
Agha Taj Mohammed ◽  
Batool Bibi ◽  
Salman Shams
Keyword(s):  
Dental Plaque ◽  
Histopathological Examination ◽  
Maxillofacial Surgery ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Care Physician ◽  
University Hospital ◽  
Anterior Region ◽  
Hormonal Imbalance ◽  
In Pregnancy

Objectives: To evaluate pattern and presentation of pyogenic granuloma in pregnant patients. Study Design: Descriptive study with non-probability purposive technique. Setting: Department of Oral & Maxillofacial Surgery Liaquat University hospital Hyderabad. Period: From February 2013 to January 2017. Material & Methods: A total number of fifty pregnant patients were included in the study and preliminary diagnosis of gingival pyogenic granuloma was made clinically. The clinical diagnosis was confirmed by excisional biopsy under local anesthesia (surgical procedure was done following consultation with primary care physician in second trimester or after parturition), and sent for histopathological examination. Removal of dental plaque performed before surgical therapy. Results: Most of the females involve were in age group of 21-30 (68%). Maxillary anterior region was most frequently involved followed by mandibular anterior region. The smallest size of lesion was 1.5mm and largest was 3cm. Conclusion: Pyogenic granuloma in pregnancy occur due to hormonal imbalance, however bacterial dental plaque, calculus and poor oral hygiene are also key factors in development.

scholarly journals Gingival Pyogenic Granuloma -Clinical Case Report

2021 ◽  
Vol 04 (11) ◽  
Author(s):  
Dr. Priyanka Aggarwal ◽  
Keyword(s):  
Case Report ◽  
Clinical Case ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Vascular Tumor ◽  
Giant Cell Granuloma ◽  
Hormonal Factors ◽  
Neoplastic Lesion ◽  
Histopathological Evaluation ◽  
Granuloma Pyogenicum

Pyogenic granuloma is a vascularized non neoplastic lesion, in the oral cavity, caused by trauma, local irritants or hormonal factors, with a higher prevalence in women, present more frequently in the mandible than in the maxilla. It is not associated with pus as its name suggests and histologically it resembles an angiomatous lesion rather than a granulomatous lesion. It is known by a variety of names such as Crocker and Hartzell’s disease, granuloma pyogenicum, granuloma pediculatum benignum, benign vascular tumor and during pregnancy as granuloma gravidarum Treatment consists of removal of local irritant, if any followed by excisional biopsy. This clinical case report presents the clinical and histopathological characteristics of the large pyogenic granuloma in a 36-year-old female, who reported to the Department of Santosh Dental College, Ghaziabad. Intraoral examination revealed a lesion mainly non tender, sessile, soft in consistency and measuring approximately 16by 9 mm in diameter in the posterior side of maxillary first quadrant. Keeping in view the characteristics of the lesion, anamnesis and the literature, the pyogenic granuloma and giant cell granuloma were defined as diagnostic hypotheses. Excisional biopsy was done and specimen was sent for histopathological evaluation.

scholarly journals Preauricular pilomatrixoma in a 3 year-old girl: A case study

2012 ◽  
Vol 18 (1) ◽  
pp. 84-86
Author(s):  
H Hirbod ◽  
F Ameli ◽  
M Swamintanhan ◽  
BS Goh
Keyword(s):  
Foreign Body Reaction ◽  
Histopathological Examination ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Clinical Feature ◽  
Sebaceous Cyst ◽  
Characteristic Clinical Feature ◽  
History Of ◽  
High Index Of Suspicion

Objectives: To report a case of preauricular pilomatrixoma in a 3-year-old girl.Methods: Retrospective review on a case reportResults: A three-year-old girl presented with six month history of painless right pre-auricular swelling that was gradually increasing in size. The mass was small, soft, non tender with normal overlying skin. She underwent excisional biopsy of lesion and histopathological examination showed pilomatrixoma. She was well post operatively and no recurrence after 2 years of follow up.Conclusion: Pilomatrixoma is often misdiagnosed clinically as epidermoid cyst, sebaceous cyst, dermoid cyst, foreign body reaction, calcification in lymph node, fat necrosis, pyogenic granuloma, chalazion and keratoacanthoma, but a high index of suspicion and careful histological examination of its characteristic clinical feature can help clinicians to differentiate it from other tumors.   DOI: http://dx.doi.org/10.3329/bjo.v18i1.10426  Bangladesh J Otorhinolaryngol 2012; 18(1): 84-86

Lobular capillary haemangioma (pyogenic granuloma) of the nose

1997 ◽  
Vol 111 (10) ◽  
pp. 941-945 ◽  
Author(s):  
Yousry El-Sayed ◽  
Awad Al-Serhani
Keyword(s):  
Differential Diagnosis ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
University Hospital ◽  
Clinical Impression ◽  
Histopathological Diagnosis ◽  
Study Group ◽  
Capillary Haemangioma ◽  
Clinicopathological Study ◽  
Diagnostic Pitfalls

AbstractObjectiveTo present a number of cases with lobular capillary haemangioma (pyogenic granuloma) of the nose; and to discuss the clinical and histopathological diagnosis of this disorder.MethodsA clinicopathological study of patients diagnosed with nasal lobular capillary haemangioma who were treated at King Abdel Aziz University Hospital, Riyadh from 1986 to 1995.ResultsThe study group consisted of 12 patients (four males and eight females ranging in age from 17 to 65 years; mean 30.1 years). Clinically, most patients presented with epistaxis and a rapidly growing unilateral haemorrhagic mass. Most lesions were located on the septal mucosa. The clinical impression was misleading in some cases. The histological diagnosis was based on the lobular arrangement of capillaries. One case was initially misdiagnosed as angiofibroma. Excisional biopsy was the mainstay of treatment. One instance of recurrence was recorded.ConclusionThis uncommon lesion should be considered in the differential diagnosis of a rapidly growing haemorrhagic lesion within the nasal fossa. Clinical and histological diagnostic pitfalls occur frequently.

scholarly journals Excisional Biopsy of the Pyogenic Granuloma in Very High-Risk Patient

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Dirceu Tavares Formiga Nery ◽  
José Ranali ◽  
Darceny Zanetta Barbosa ◽  
Helvécio Marangon Júnior ◽  
Rafael Martins Afonso Pereira ◽  
...  
Keyword(s):  
High Risk ◽  
Dental Treatment ◽  
Oral Surgery ◽  
High Risk Patient ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Risk Patient ◽  
Coronary Insufficiency ◽  
Systemic Complications ◽  
Arterial Blood

Oral surgery to remove pyogenic granuloma in a high-risk patient is reported. A 47-year-old man with gastroesophageal reflux disease, diabetes mellitus II, dyslipidemia, and chronic coronary insufficiency (myocardial infarction within 2 years) with episodes of unstable angina was submitted to an excisional biopsy of hemorrhagic lesion in the lingual right mandibular gingiva. During dental treatment, the arterial blood pressure, oxygen saturation, heart rate, and electrocardiogram were monitored. Local anesthesia was performed with 0.45 ml of 3% prilocaine with 0.03 IU/ml felypressin. The anticoagulant therapy was not interrupted. No local or systemic complications were noticed during or after the surgery.

scholarly journals Angiosarcoma of the scalp

2009 ◽  
Vol 42 (01) ◽  
pp. 118-121
Author(s):  
Manjiri DasGupta ◽  
Nilay Chakrabarti ◽  
Pravin Agrawal ◽  
Swati Narurkar
Keyword(s):  
Postoperative Radiotherapy ◽  
Excisional Biopsy ◽  
Pyogenic Granuloma ◽  
Wide Excision ◽  
Soft Tissue Tumour ◽  
Small Plaque ◽  
Second Stage ◽  
Local Rotation ◽  
Tissue Tumour ◽  
Scalp Lesion

ABSTRACTAngiosarcoma is a relatively rare soft tissue tumour. It usually occurs in the head and neck, and especially in the scalp, in elderly people. Its presentation varies from a small plaque to multifocal nodules. The treatment depends on the extent of the disease. Most cases are treated with wide excision with reconstruction. Radiotherapy and chemotherapy are advocated in the recurrent or extensive lesions with regional or distant metastasis. Other modalities such as immunomodulation have been tried. A case of a 55-year-old female patient with a bleeding scalp lesion is presented. Initially thought to be a pyogenic granuloma, on excisional biopsy it was diagnosed as angiosarcoma with microscopic involvement of the margins. Wide excision with reconstruction using a local rotation flap was done at a second stage. The patient was not given postoperative radiotherapy or chemotherapy. There has been no recurrence for two years.

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