scholarly journals Obtaining Deep Learning Models for Automatic Classification of Leukocytes

Author(s):  
Pedro João Rodrigues ◽  
Getúlio Peixoto Igrejas ◽  
Romeu Ferreira Beato

In this work, the authors classify leukocyte images using the neural network architectures that won the annual ILSVRC competition. The classification of leukocytes is made using pretrained networks and the same networks trained from scratch in order to select the ones that achieve the best performance for the intended task. The categories used are eosinophils, lymphocytes, monocytes, and neutrophils. The analysis of the results takes into account the amount of training required, the regularization techniques used, the training time, and the accuracy in image classification. The best classification results, on the order of 98%, suggest that it is possible, considering a competent preprocessing, to train a network like the DenseNet with 169 or 201 layers, in about 100 epochs, to classify leukocytes in microscopy images.

Proceedings ◽  
2020 ◽  
Vol 47 (1) ◽  
pp. 9 ◽  
Author(s):  
Stefan Leijnen ◽  
Fjodor van Veen

An overview of neural network architectures is presented. Some of these architectures have been created in recent years, whereas others originate from many decades ago. Apart from providing a practical tool for comparing deep learning models, the Neural Network Zoo also uncovers a taxonomy of network architectures, their chronology, and traces back lineages and inspirations for these neural information processing systems.


Proceedings ◽  
2020 ◽  
Vol 47 (1) ◽  
pp. 9
Author(s):  
Stefan Leijnen ◽  
Fjodor van Veen

An overview of neural network architectures is presented. Some of these architectures have been created in recent years, whereas others originate from many decades ago. Apart from providing a practical tool for comparing deep learning models, the Neural Network Zoo also uncovers a taxonomy of network architectures, their chronology, and traces back lineages and inspirations for these neural information processing systems.


Author(s):  
T.K. Biryukova

Classic neural networks suppose trainable parameters to include just weights of neurons. This paper proposes parabolic integrodifferential splines (ID-splines), developed by author, as a new kind of activation function (AF) for neural networks, where ID-splines coefficients are also trainable parameters. Parameters of ID-spline AF together with weights of neurons are vary during the training in order to minimize the loss function thus reducing the training time and increasing the operation speed of the neural network. The newly developed algorithm enables software implementation of the ID-spline AF as a tool for neural networks construction, training and operation. It is proposed to use the same ID-spline AF for neurons in the same layer, but different for different layers. In this case, the parameters of the ID-spline AF for a particular layer change during the training process independently of the activation functions (AFs) of other network layers. In order to comply with the continuity condition for the derivative of the parabolic ID-spline on the interval (x x0, n) , its parameters fi (i= 0,...,n) should be calculated using the tridiagonal system of linear algebraic equations: To solve the system it is necessary to use two more equations arising from the boundary conditions for specific problems. For exam- ple the values of the grid function (if they are known) in the points (x x0, n) may be used for solving the system above: f f x0 = ( 0) , f f xn = ( n) . The parameters Iii+1 (i= 0,...,n−1 ) are used as trainable parameters of neural networks. The grid boundaries and spacing of the nodes of ID-spline AF are best chosen experimentally. The optimal selection of grid nodes allows improving the quality of results produced by the neural network. The formula for a parabolic ID-spline is such that the complexity of the calculations does not depend on whether the grid of nodes is uniform or non-uniform. An experimental comparison of the results of image classification from the popular FashionMNIST dataset by convolutional neural 0, x< 0 networks with the ID-spline AFs and the well-known ReLUx( ) =AF was carried out. The results reveal that the usage x x, ≥ 0 of the ID-spline AFs provides better accuracy of neural network operation than the ReLU AF. The training time for two convolutional layers network with two ID-spline AFs is just about 2 times longer than with two instances of ReLU AF. Doubling of the training time due to complexity of the ID-spline formula is the acceptable price for significantly better accuracy of the network. Wherein the difference of an operation speed of the networks with ID-spline and ReLU AFs will be negligible. The use of trainable ID-spline AFs makes it possible to simplify the architecture of neural networks without losing their efficiency. The modification of the well-known neural networks (ResNet etc.) by replacing traditional AFs with ID-spline AFs is a promising approach to increase the neural network operation accuracy. In a majority of cases, such a substitution does not require to train the network from scratch because it allows to use pre-trained on large datasets neuron weights supplied by standard software libraries for neural network construction thus substantially shortening training time.


Author(s):  
Parvathi R. ◽  
Pattabiraman V.

This chapter proposes a hybrid method for classification of the objects based on deep neural network and a similarity-based search algorithm. The objects are pre-processed with external conditions. After pre-processing and training different deep learning networks with the object dataset, the authors compare the results to find the best model to improve the accuracy of the results based on the features of object images extracted from the feature vector layer of a neural network. RPFOREST (random projection forest) model is used to predict the approximate nearest images. ResNet50, InceptionV3, InceptionV4, and DenseNet169 models are trained with this dataset. A proposal for adaptive finetuning of the deep learning models by determining the number of layers required for finetuning with the help of the RPForest model is given, and this experiment is conducted using the Xception model.


Electronics ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 427 ◽  
Author(s):  
Laith Alzubaidi ◽  
Mohammed A. Fadhel ◽  
Omran Al-Shamma ◽  
Jinglan Zhang ◽  
Ye Duan

Sickle cell anemia, which is also called sickle cell disease (SCD), is a hematological disorder that causes occlusion in blood vessels, leading to hurtful episodes and even death. The key function of red blood cells (erythrocytes) is to supply all the parts of the human body with oxygen. Red blood cells (RBCs) form a crescent or sickle shape when sickle cell anemia affects them. This abnormal shape makes it difficult for sickle cells to move through the bloodstream, hence decreasing the oxygen flow. The precise classification of RBCs is the first step toward accurate diagnosis, which aids in evaluating the danger level of sickle cell anemia. The manual classification methods of erythrocytes require immense time, and it is possible that errors may be made throughout the classification stage. Traditional computer-aided techniques, which have been employed for erythrocyte classification, are based on handcrafted features techniques, and their performance relies on the selected features. They also are very sensitive to different sizes, colors, and complex shapes. However, microscopy images of erythrocytes are very complex in shape with different sizes. To this end, this research proposes lightweight deep learning models that classify the erythrocytes into three classes: circular (normal), elongated (sickle cells), and other blood content. These models are different in the number of layers and learnable filters. The available datasets of red blood cells with sickle cell disease are very small for training deep learning models. Therefore, addressing the lack of training data is the main aim of this paper. To tackle this issue and optimize the performance, the transfer learning technique is utilized. Transfer learning does not significantly affect performance on medical image tasks when the source domain is completely different from the target domain. In some cases, it can degrade the performance. Hence, we have applied the same domain transfer learning, unlike other methods that used the ImageNet dataset for transfer learning. To minimize the overfitting effect, we have utilized several data augmentation techniques. Our model obtained state-of-the-art performance and outperformed the latest methods by achieving an accuracy of 99.54% with our model and 99.98% with our model plus a multiclass SVM classifier on the erythrocytesIDB dataset and 98.87% on the collected dataset.


2020 ◽  
Vol 17 (8) ◽  
pp. 3478-3483
Author(s):  
V. Sravan Chowdary ◽  
G. Penchala Sai Teja ◽  
D. Mounesh ◽  
G. Manideep ◽  
C. T. Manimegalai

Road injuries are a big drawback in society for a few time currently. Ignoring sign boards while moving on roads has significantly become a major cause for road accidents. Thus we came up with an approach to face this issue by detecting the sign board and recognition of sign board. At this moment there are several deep learning models for object detection using totally different algorithms like RCNN, faster RCNN, SPP-net, etc. We prefer to use Yolo-3, which improves the speed and precision of object detection. This algorithm will increase the accuracy by utilizing residual units, skip connections and up-sampling. This algorithm uses a framework named Dark-net. This framework is intended specifically to create the neural network for training the Yolo algorithm. To thoroughly detect the sign board, we used this algorithm.


2021 ◽  
Author(s):  
Ghassan Mohammed Halawani

The main purpose of this project is to modify a convolutional neural network for image classification, based on a deep-learning framework. A transfer learning technique is used by the MATLAB interface to Alex-Net to train and modify the parameters in the last two fully connected layers of Alex-Net with a new dataset to perform classifications of thousands of images. First, the general common architecture of most neural networks and their benefits are presented. The mathematical models and the role of each part in the neural network are explained in detail. Second, different neural networks are studied in terms of architecture, application, and the working method to highlight the strengths and weaknesses of each of neural network. The final part conducts a detailed study on one of the most powerful deep-learning networks in image classification – i.e. the convolutional neural network – and how it can be modified to suit different classification tasks by using transfer learning technique in MATLAB.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e16097-e16097
Author(s):  
Andrew J. Kruger ◽  
Lingdao Sha ◽  
Madhavi Kannan ◽  
Rohan P. Joshi ◽  
Benjamin D. Leibowitz ◽  
...  

e16097 Background: Using gene-expression, consensus molecular subtypes (CMS) divide colorectal cancers (CRC) into four categories with prognostic and therapy-predictive clinical utilities. These subtypes also manifest as different morphological phenotypes in whole-slide images (WSIs). Here, we implemented and trained a novel deep multiple instance learning (MIL) framework that requires only a single label per WSI to identify morphological biomarkers and accelerate CMS classification. Methods: Deep learning models can be trained by MIL frameworks to classify tissue in localized tiles from large ( > 1 Gb) WSIs using only weakly supervised, slide-level classification labels. Here we demonstrate a novel framework that advances on instance-based MIL by using a multi-phase approach to training deep learning models. The framework allows us to train on WSIs that contain multiple CMS classes while further identifying previously undiscovered tissue features that have low or no correlation with any subtype. Identification of these uncorrelated features results in improved insights into the specific tissue features that are most associated with the four CMS classes and a more accurate classification of CMS status. Results: We trained and validated (n = 735 WSIs and 184 withheld WSIs, respectively) a ResNet34 convolutional neural network to classify 224x224 pixel tiles distributed across tumor, lymphocyte, and stroma tissue regions. The slide-level CMS classification probability was calculated by an aggregation of the tiles correlated with each one of the four subtypes. The receiver operating characteristic curves had the following one-vs-all AUCs: CMS1 = 0.854, CMS2 = 0.921, CMS3 = 0.850, and CMS4 = 0.866, resulting in an average AUC of 0.873. Initial tests to generalize to other data sets, such as TCGA, are promising and constitute one of the future directions of this work. Conclusions: The MIL framework robustly identified tissue features correlated with CMS groups, allowing for a more efficient classification of CRC samples. We also demonstrated that the morphological features indicative of different molecular subtypes can be identified from the deep neural network.


Author(s):  
Ahlam Wahdan ◽  
Sendeyah AL Hantoobi ◽  
Said A. Salloum ◽  
Khaled Shaalan

Classifying or categorizing texts is the process by which documents are classified into groups by subject, title, author, etc. This paper undertakes a systematic review of the latest research in the field of the classification of Arabic texts. Several machine learning techniques can be used for text classification, but we have focused only on the recent trend of neural network algorithms. In this paper, the concept of classifying texts and classification processes are reviewed. Deep learning techniques in classification and its type are discussed in this paper as well. Neural networks of various types, namely, RNN, CNN, FFNN, and LSTM, are identified as the subject of study. Through systematic study, 12 research papers related to the field of the classification of Arabic texts using neural networks are obtained: for each paper the methodology for each type of neural network and the accuracy ration for each type is determined. The evaluation criteria used in the algorithms of different neural network types and how they play a large role in the highly accurate classification of Arabic texts are discussed. Our results provide some findings regarding how deep learning models can be used to improve text classification research in Arabic language.


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