Prebiotic Aggregates (Tissues) Emerging from Reaction–Diffusion: Formation Time, Configuration Entropy and Optimal Spatial Dimension

For the formation of a proto-tissue, rather than a protocell, the use of reactant dynamics in a finite spatial region is considered. The framework is established on the basic concepts of replication, diversity, and heredity. Heredity, in the sense of the continuity of information and alike traits, is characterized by the number of equivalent patterns conferring viability against selection processes. In the case of structural parameters and the diffusion coefficient of ribonucleic acid, the formation time ranges between a few years to some decades, depending on the spatial dimension (fractional or not). As long as equivalent patterns exist, the configuration entropy of proto-tissues can be defined and used as a practical tool. Consequently, the maximal diversity and weak fluctuations, for which proto-tissues can develop, occur at the spatial dimension 2.5.

Thermographic Screening of Beef Cattle Metatarsal Growth Plate Lesions

Lameness represents one of the main causes of decreased productive performance and impaired animal welfare in the bovine industry. Young beef bulls are predisposed to develop diseases of the growing skeleton, especially growth plate lesions. Early diagnosis is indispensable for ensuring correct treatment, fast recovery and reduction losses. However, when dealing with beef cattle, this is not always possible. Fast and reliable diagnostic imaging techniques are necessary to improve dealing with lameness in beef animals. The aim of the present study was to examine the potential of thermographic imaging as a non-invasive tool for rapidly screening beef bulls for the presence of growth plate lesions. Here, 20 Charolais and Limousine beef bulls affected by growth plate lesions in one of the rear limbs were selected. IRT was performed on both hind limbs using a digital infrared camera (ThermaCam T420 Model, Flir Systems, Boston, MA, USA), prior to radiographic imaging and clinical examination. The temperature of healthy and affected limbs was measured in two regions: the area correspondent to the growth plate (AR01) and the whole area of the metatarsus (AR02). Growth plate lesions were found to increase the maximum, mean, and minimum temperatures in AR01; and the mean and maximum temperatures in AR02, therefore, indicating the potential of IRT as a reliable, practical tool for screening growth plate lesions in beef bulls.

The dark halo technique in the oeuvre of Michael Sweerts and other Flemish and Dutch baroque painters. A 17th c. empirical solution to mitigate the optical ‘simultaneous contrast’ effect?

Although the topic is rarely addressed in literature, a significant number of baroque paintings exhibit dark, halo-like shapes around the contours of the dramatis personae. Close examination of both finished and unfinished works suggests that this intriguing feature was a practical tool that helped the artist in the early painting stages. When applying the final brushwork, the halo lost its function, with some artists undertaking efforts to hide it. Although their visibility might not have been intended by the artists, today this dark paint beneath the surface is partially visible through the upper paint layers. Moreover, the disclosure of many halos using infrared photography (IRP), infrared reflectography (IRR) and macro X-ray fluorescence imaging (MA-XRF), additional to those that can be observed visually, suggests that this was a common and established element of 17th-century painting practice in Western Europe. Building on an existing hypothesis, we argue that halos can be considered as a solution to an optical problem that arose when baroque painters reversed the traditional, 15th- and 16th-century painting sequence of working from background to foreground. Instead, they started with the dominant parts of a composition, such as the face of a sitter. In that case, a temporary halo can provide the essential tonal reference to anticipate the chromatic impact of the final dark colored background on the adjacent delicate carnations. In particular, we attempt to clarify the prevalence of dark halos as a response to optical effects such as ‘simultaneous contrast’ and ‘the crispening effect’, described in literature only centuries later. As such, the recently termed ‘ring condition’ can be seen as the present-day equivalent of the ‘halo solution’ that was seemingly empirically or intuitively developed by 17th-century artists. Modern studies in visual perception proves that by laying a black ring around a target color, the optical impact of a surrounding color can be efficiently neutralized. Finally, by delving into works by Michael Sweerts, it becomes clear that resourceful artists might have adapted the halo technique and the underlying principles to their individual challenges, such as dealing with differently colored grounds.

Association between a single measurement of progesterone and cortisol blood concentrations at two to one week before parturition, and number of fetuses in the Teramana goat

The Teramana goat is an at-risk breed, needing population protection and programs to increase their numbers. The first step for a population increase is the best management of reproduction, leading to an as high as possible number of healthy and viable kids born. To this purpose, beside the optimization of mating, the best possible management of pregnancy and parturition is mandatory. The goat is a prolific farm animal in which single, double, or triple ovulations can occur, leading to singleton, twin or triple pregnancies, and the birth of multiple kids. Twins and triplets are associated to increased risk for perinatal mortality and need a special surveillance and possible assistance at birth. Knowledge of the number of fetuses that have to be delivered from each goat could be a practical tool for a better management of parturition. Among the methods to define the number of fetuses in the goat, the measurement of blood progesterone (P4) concentrations have provided inconsistent results. Therefore, the present study was aimed to assess the possible association between the maternal concentrations of plasma P4 and cortisol (C), two hormones possibly associated to the number of fetuses, measured only once at about two to one week before parturition in Teramana goats, and the number of fetuses. The results, obtained from 23 does, showed that both plasma P4 and C are higher in does bearing multiple fetuses than does with singleton pregnancies. However, the single measurement of plasma C, but not P4, two to one week before the expected parturition in the Teramana goat is useful to distinguish between does bearing singleton and triplet pregnancies for a better surveillance and assistance at delivery. Therefore, it could represent a tool for the best management of reproduction in a breed population at risk for extinction.

PENGEMBANGAN MEDIA PENGUKUR VOLUME BENDA BERBENTUK TIDAK TERATUR BERBAHAN WADAH MINUMAN BEKAS PADA MASA “PTMT”

This study aims to produce a product in the form of a medium for measuring the volume of irregularly shaped objects, made from used drink containers. The type of media developed is in the form of practical aids. This research includes development research known as Research and Development. During the limited face-to-face learning period (PTMT) the learning process must be designed as effectively as possible, because students study at school for only about 4 hours, without rest. The existence of practical aids is very helpful for students' understanding of the concepts explained by the teacher, but not all schools have laboratory equipment that is proportional to the number of students. To overcome this problem, a solution is given to develop a practical tool made from used drink containers for measuring the volume of irregularly shaped objects. Before the practical aids were tested, they were validated by material experts and material experts. The average results of the two validation experts. obtained a score of 97.05% with a very decent category. The media trial included a limited test consisting of 12 students of class VII/B and a broad test which was carried out on all students of class VII/B of 32 students. The results of the limited test obtained an average of 98.3%, and in the broad test an average of 99% was obtained with a very decent predicate as well. After the trial, the students were given a set of test tools in the form of questions related to the material for measuring the volume of objects with irregular shapes. The results of the tests completed by students after using the developed media, students who scored above the KKM were 96%, this indicates that the developed media is feasible to use and can help students understand the concept of measuring the volume of irregularly shaped objects. ABSTRAKPenelitian ini bertujuan untuk menghasilkan produk berupa media pengukur volume benda yang berbentuk tidak teratur, berbahan wadah minuman bekas. Jenis media yang dikembangkan berupa alat bantu praktik. Penelitian ini termasuk penelitian pengembangan yang dikenal dengan istilah Research and Development. Pada masa pembelajaran dengan tatap muka terbatas (PTMT) proses pembelajaran harus di rancang seefektif mungkin, karena siswa belajar di sekolah hanya sekitar 4 jam, tanpa istirahat. Keberadaan alat bantu praktik sangat membantu pemahaman siswa terhadap konsep yang dijelaskan guru, namun tidak semua sekolah memiliki peralatan laboratorium yang sebanding dengan jumlah siswa. Untuk mengatasi masalah tersebut diberikan solusi mengembangkan alat bantu praktik berbahan wadah minuman bekas pada pengukuran volume benda berbentuk tidak teratur. Sebelum alat bantu praktik diuji cobakan, dilakukan validasi oleh ahli materi dan ahli materi. Hasil rata-rata dari kedua ahli validasi . diperoleh scor 97,05% dengan kategori sangat layak. Uji coba media meliputi uji terbatas yang terdiri dari 12 siswa kelas VII/B dan uji luas yang dilaksanakan pada seluruh siswa kelas VII/B sejumlah 32 siswa. Hasil uji terbatas diperoleh rata-rata 98,3%, dan pada uji luas diperoleh rata-rata 99% dengan predikat sangat layak juga. Setelah dilakukan uji coba siswa diberikan seperangkat alat tes berupa soal yang berkaitan dengan materi pengukuran volume benda yang bentuknya tidak teratur. Hasil test yang diselesaikan oleh siswa setelah menggunakan media yang dikembangkan, siswa yang memperoleh nilai diatas KKM adalah 96%, hal ini menunjukkan bahwa media yang dikembangkan layak digunakan dan dapat membantu pemahaman siswa dalam mempelajari konsep pengukuran volume benda yang berbentuk tidak teratur.

Ubi-SleepNet

Sleep is a fundamental physiological process that is essential for sustaining a healthy body and mind. The gold standard for clinical sleep monitoring is polysomnography(PSG), based on which sleep can be categorized into five stages, including wake/rapid eye movement sleep (REM sleep)/Non-REM sleep 1 (N1)/Non-REM sleep 2 (N2)/Non-REM sleep 3 (N3). However, PSG is expensive, burdensome and not suitable for daily use. For long-term sleep monitoring, ubiquitous sensing may be a solution. Most recently, cardiac and movement sensing has become popular in classifying three-stage sleep, since both modalities can be easily acquired from research-grade or consumer-grade devices (e.g., Apple Watch). However, how best to fuse the data for greatest accuracy remains an open question. In this work, we comprehensively studied deep learning (DL)-based advanced fusion techniques consisting of three fusion strategies alongside three fusion methods for three-stage sleep classification based on two publicly available datasets. Experimental results demonstrate important evidences that three-stage sleep can be reliably classified by fusing cardiac/movement sensing modalities, which may potentially become a practical tool to conduct large-scale sleep stage assessment studies or long-term self-tracking on sleep. To accelerate the progression of sleep research in the ubiquitous/wearable computing community, we made this project open source, and the code can be found at: https://github.com/bzhai/Ubi-SleepNet.

A Conceptual Framework for Heritage Impact Assessment: A Review and Perspective

Heritage Impact Assessment (HIA) has recently emerged as a conflict-solving tool to improve World Heritage (WH) conservation in line with sustainable development policies. The increasing number of requested HIAs for affected WH properties over the last years reveals that more attention is being paid to HIA as a practical tool to adequately support the protection and management of historic monuments and sites against new constructions and development. However, the application of integrated and systematic impact assessment methods within HIA still remains a key challenge in different HIA projects. Therefore, this paper contributes to the further development of a transparent and systematic procedure of HIA in accordance with Environmental Impact Assessment (EIA). It also explores different standard methods of impact assessment in EIA and discusses their applicability to cultural World Heritage properties. Finally, the paper emphasizes a need for developing integrated impact assessment methods to address the multiple impacts of development projects. Such methodological enhancement can further contribute to mitigation strategies and decision-making to protect World Heritage properties within the context of sustainable development.

Cooperative passing network features are associated with successful match outcomes in the Australian Football League

Collective behaviour is an important component of team performance in team sports. This study used a binomial generalised linear mixed effects regression model to investigate the relationship between cooperative passing network characteristics and match outcomes of professional Australian Football League competition games across four seasons between 2016 and 2019. It divided a sample of 1629 observations into a training and testing partition used to develop and assess the validity of the model used in this study, respectively. The results of this study reveal that a team's connectedness is associated with the probability of winning Australian Football League games (Akaike Information Criterion = 1637.3, residual df= 1297, deviance = 1625.3). When most players within a team are involved in the team's passing network bidirectionally (i.e. a well-connected network; odds ratio = 1.053; 95% confidence interval: 4.2–6.5%, p < 0.001), teams have a higher probability of winning. The centralisation of a team's passing network was not significantly related to match outcomes. The classification accuracy for the model associating network characteristics with match outcomes was 69%. Collectively, these findings suggest that Australian Football League-specific network features should be incorporated within existing performance analysis methods and can provide a useful, practical tool for coaches to measure collective performance during team practice.

Active Ageing: The Need to Address Sub-National Diversity. An Evidence-Based Approach for Italy

While active ageing has emerged as a main strategy to address the challenges of population ageing in Europe, recent research has stressed the need to increase knowledge on within-country differences to promote active ageing through appropriate policy responses. This article draws on the Active Ageing Index (AAI) to capture recent trends in active ageing in Italy with a focus on sub-national diversity. To this end, we compute AAI breakdowns by region separately for men and women for four different years: 2007, 2009, 2012 and 2018. Then, we use linear regression to describe the geographical and sex-specific patterns of change in the AAI over the considered period. The results demonstrate the diversity of regional outcomes and trends in the active ageing of Italian men and women, indicating that the widening geographic gap deserves further consideration by national and regional authorities in designing and implementing active ageing policies. By showing the persistence of disparities in the value of the indicator to the disadvantage of women, results also suggest the need to further integrate both the gender dimension and the life-cycle perspective into active ageing strategies. This article provides an example of how the AAI can be used as a practical tool by policy makers to monitor active ageing trends and outcomes at the sub-national level, and to identify target areas that require further action.