biological application
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Author(s):  
Kellen Cruvinel Rodrigues Andrade ◽  
◽  
Diegue Henrique Nascimiento Martins ◽  
Diogo de Amorim Barros ◽  
Paula Monteiro de Souza ◽  
...  

The purpose of this systematic review was to identify the available literature on the essential oil from species of genus Cordia. This study followed the Preferred Reporting Items for Systematic Reviews. The search was conducted on four databases: LILACS, PubMed, Science Direct, and Scopus until June 5th, 2020, with no time or language restrictions. Sixty out of the 1,333 initially gathered studies fit the inclusion criteria after the selection process. Nine species of Cordiawere reported in the selected studies, out of which 79% of the evaluated studies reported essential oil from Cordia curassavica. The essential oil extraction methods identified were hydrodistillation and steam distillation. As for biological application, antimicrobial, anti-inflammatory, larvicidal and antioxidant activities were the most reported. The main compounds reported for essential oil were β-caryophyllene, α-humulene, α-pinene, bicyclogermacrene, and sabinene. The information reported in this systematic review can contribute scientifically to the recognition of the importance of the genus Cordia.


Author(s):  
Benzhao He ◽  
Jiachang Huang ◽  
Jianyu Zhang ◽  
Herman H. Y. Sung ◽  
Jacky W. Y. Lam ◽  
...  

2022 ◽  
Author(s):  
Benzhao He ◽  
Jiachang Huang ◽  
Jianyu Zhang ◽  
Herman H. Y. Sung ◽  
Jacky W. Y. Lam ◽  
...  

Pharmaceutics ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 141
Author(s):  
Bruna Carvalho ◽  
Bruno Ceccato ◽  
Mariano Michelon ◽  
Sang Han ◽  
Lucimara de la Torre

Microfluidics is an emerging technology that can be employed as a powerful tool for designing lipid nano-microsized structures for biological applications. Those lipid structures can be used as carrying vehicles for a wide range of drugs and genetic materials. Microfluidic technology also allows the design of sustainable processes with less financial demand, while it can be scaled up using parallelization to increase production. From this perspective, this article reviews the recent advances in the synthesis of lipid-based nanostructures through microfluidics (liposomes, lipoplexes, lipid nanoparticles, core-shell nanoparticles, and biomimetic nanovesicles). Besides that, this review describes the recent microfluidic approaches to produce lipid micro-sized structures as giant unilamellar vesicles. New strategies are also described for the controlled release of the lipid payloads using microgels and droplet-based microfluidics. To address the importance of microfluidics for lipid-nanoparticle screening, an overview of how microfluidic systems can be used to mimic the cellular environment is also presented. Future trends and perspectives in designing novel nano and micro scales are also discussed herein.


2022 ◽  
Vol 24 (1) ◽  
pp. 34-47
Author(s):  
Pankaj S. Kore ◽  
◽  
Santosh K. Singh ◽  
Shrinivas K. Mohite ◽  
◽  
...  

The most of drugs containing Benzimidazole ring is a prominent structural motif found in numerous therapeutically active compounds. Benzimidazole and its synthetic analogues have been found to exhibit industrial, agricultural and biological application such as antitubercular, anti-inflammatory, analgesic, anticancer, anticoagulant, as well as good antifungal and anti microbial activity. Recent advances in technology considers microwave irradiation energy as the most efficient means of heating reactions for chemical transformations that can be accomplished in a minutes. Microwave irradiation assists organic synthesis (MAOS) not only helps in implementing green chemistry but also led to progress in organic synthesis. We report pharmacological screening of some novel 2 substituted and 1(h)-substituted Benzimidazole derivatives.


Author(s):  
Sajjad Husain Mir ◽  
M. K. Mohammad Ziaul Hyder ◽  
A. M. Masudul Azad Chowdhury

2021 ◽  
Vol 6 (4) ◽  
pp. 315-321
Author(s):  
Ashokbhai R. Rathod ◽  
Kapil Kumar Galachar ◽  
Chandan Kumar Pashavan ◽  
Sushil S. Korgaokar ◽  
Yogesh T. Naliapara

In current times, researchers adopted the click chemistry approach for the synthesis of various druglike molecules by using a few reliable, feasible, practical and selective chemical transformations via click formation. In present work, we focussed on the most triazole clubbed thiazolidine-2,4-dione derivatives as the most promising motifs for broad biological application. A total of fifteen (CF-4a-o) derivatives were synthesized and well characterized with various analytical techniques.


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