coupled spin systems
Recently Published Documents


TOTAL DOCUMENTS

104
(FIVE YEARS 6)

H-INDEX

22
(FIVE YEARS 1)

2021 ◽  
Author(s):  
Johanna Dorst ◽  
Tamas Borbath ◽  
Loreen Ruhm ◽  
Anke Henning

A method to estimate phosphorus (31P) transversal relaxation times (T2) of coupled spin systems is demonstrated. Additionally, intracellular and extracellular pH (pHext, pHint) and relaxation corrected metabolite concentrations are reported. Echo time (TE) series of 31P metabolite spectra were acquired using STEAM localization. Spectra were fitted using LCModel with accurately modeled Vespa basis sets accounting for J−evolution of the coupled spin systems. T2s were estimated by fitting a single exponential two−parameter model across the TE series. Fitted inorganic phosphate frequencies were used to calculate pH, and relaxation times were used to determine the brain metabolite concentrations. The method was demonstrated in the healthy human brain at a field strength of 9.4T. T2 relaxation times of ATP and NAD are the shortest between 8 ms and 20 ms, followed by T2s of inorganic phosphate between 25 ms and 50 ms, and PCr with a T2 of 100 ms. Phosphomonoesters and −diesters have the longest T2s of about 130 ms. Measured T2s are comparable to literature values and fit in a decreasing trend with increasing field strengths. Calculated pHs and metabolite concentrations are also comparable to literature values


2021 ◽  
Author(s):  
Peter Kiraly ◽  
Guilherme Dal Poggetto ◽  
Laura Castañar ◽  
Mathias Nilsson ◽  
Andrea Deák ◽  
...  

Existing methods for measuring transverse relaxation give incorrect results in coupled spin systems. Measuring true relaxation rates extends their utility.


2019 ◽  
Vol 408 ◽  
pp. 1-50 ◽  
Author(s):  
Bálint Koczor ◽  
Robert Zeier ◽  
Steffen J. Glaser

2018 ◽  
Vol 289 ◽  
pp. 55-62 ◽  
Author(s):  
S. Bussandri ◽  
I. Prina ◽  
R.H. Acosta ◽  
L. Buljubasich

2015 ◽  
Vol 91 (4) ◽  
Author(s):  
Ariane Garon ◽  
Robert Zeier ◽  
Steffen J. Glaser

Sign in / Sign up

Export Citation Format

Share Document