Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions

Background: The reproducibility of mitral regurgitation (MR) quantification by cardiovascular magnetic resonance (CMR) imaging using different software solutions remains unclear. This research aimed to investigate the reproducibility of MR quantification between two software solutions: MASS (version 2019 EXP, LUMC, Netherlands) and CAAS (version 5.2, Pie Medical Imaging). Methods: CMR data of 35 patients with MR (12 primary MR, 13 mitral valve repair/replacement, and ten secondary MR) was used. Four methods of MR volume quantification were studied, including two 4D-flow CMR methods (MRMVAV and MRJet) and two non-4D-flow techniques (MRStandard and MRLVRV). We conducted within-software and inter-software correlation and agreement analyses. Results: All methods demonstrated significant correlation between the two software solutions: MRStandard (r=0.92, p<0.001), MRLVRV (r=0.95, p<0.001), MRJet (r=0.86, p<0.001), and MRMVAV (r=0.91, p<0.001). Between CAAS and MASS, MRJet and MRMVAV, compared to each of the four methods, were the only methods not to be associated with significant bias. Conclusions: We conclude that 4D-flow CMR methods demonstrate equivalent reproducibility to non-4D-flow methods but greater levels of agreement between software solutions.

The COVID-19 Inflation Weighting in Israel

Significant shifts in the composition of consumer spending as a result of the COVID-19 crisis can complicate the interpretation of official inflation data, which are calculated by the Central Bureau of Statistics (CBS) based on a fixed basket of goods. We focus on Israel as a country that experienced three lockdowns, additional restrictions that significantly changed consumer behavior, and a successful vaccination campaign that has led to the lifting of most of these restrictions. We use credit card spending data to construct a consumption basket of goods representing the composition of household consumption during the COVID-19 period. We use this synthetic COVID-19 basket to calculate the adjusted inflation rate that should prevail during the pandemic period. We find that the differences between COVID-19-adjusted and CBS (unadjusted) inflation measures are transitory. Only the contribution of certain goods and services, particularly housing and transportation, to inflation changed significantly, especially during the first and second lockdowns. Although lockdowns and restrictions in developed countries created a significant bias in inflation weighting, the inflation bias remained unexpectedly small and transitory during the COVID-19 period in Israel.

Impact of 3D Cloud Structures on the Atmospheric Trace Gas Products from UV-VIS Sounders – Part II: impact on NO₂ retrieval and mitigation strategies

Operational retrievals of tropospheric trace gases from space-borne spectrometers are based on one-dimensional radiative transfer models. To minimize cloud effects, trace gas retrievals generally implement Lambertian cloud models based on radiometric cloud fraction estimates and photon path length corrections. The latter relies on measurements of the oxygen collision pair (O2-O2) absorption at 477 nm or on the oxygen A-band around 760 nm. In reality however, the impact of clouds is much more complex, involving unresolved sub-pixel clouds, scattering of clouds in neighboring pixels and cloud shadow effects, such that unresolved three-dimensional effects due to clouds may introduce significant biases in trace gas retrievals. In order to quantify this impact, we study NO2 as a trace gas example, and apply standard retrieval methods including approximate cloud corrections to synthetic data generated by the state-of-the-art three-dimensional Monte Carlo radiative transfer model MYSTIC. A sensitivity study is performed for simulations including a box-cloud, and the dependency on various parameters is investigated. The most significant bias is found for cloud shadow effects under polluted conditions. Biases depend strongly on cloud shadow fraction, NO2 profile, cloud optical thickness, solar zenith angle, and surface albedo. Several approaches to correct NO2 retrievals under cloud shadow conditions are explored. We find that air mass factors calculated using fitted surface albedo or corrected using the O2-O2 slant column density can partly mitigate cloud shadow effects. However, these approaches are limited to cloud-free pixels affected by surrounding clouds. A parameterization approach is presented based on relationships derived from the sensitivity study. This allows identifying measurements for which the standard NO2 retrieval produces a significant bias, and therefore provides a way to improve the current data flagging approach.

When Linda meets Preeti: The Validation of Behavioral Biases in India

This paper presents results from an experiment testing 10 of the core biases from the behavioral economics literature amongst two distinct ‘non-WEIRD’ (Western Educated Industrialized Rich and Democratic) population groups: low-income Indians, and university students from an elite Indian university. The study tests for both the existence of the ‘behavioral bias’ for each measure with our ‘non-WEIRD’ sample and tests for heterogeneity across the socioeconomically distinct sub-samples. We find that both sub-samples display significant 'bias' in the majority of tests and across different categories of bias, suggesting that behavioral biases are not peculiar to Western samples. We further find that the patterns of bias are the same for each sub-sample for most measures, but that there are notable exceptions for a small subset of measures. In most of these cases, the student sample, closer to typical samples for this type of research, shows stronger bias than the low-income sample.

Statistical Evaluation of RCM’s Performances in simulation of Climate variables at Upper Awash Basin, Case study of Akaki Catchment

The main focus of this study was to investigate and evaluate the Performance of Four Regional Climate Models irrespective of their capability in simulating mean precipitation and Temperature. In this fact and concern, the evaluation of those climate models was basically on how they simulate mean annual climatology, annual cycle and interannual variability of precipitation, maximum and minimum temperature over the entire catchment. All observed data used for the baseline period of 1980-2006 was obtained from Ethiopian National Meteorological Agency and RCM data was extracted from CORDEX-Africa-44 using grid points. RCM shows significant bias and almost all of them simulate those climate variables' at different levels. In the analysis of the annual cycle of precipitation during the summer season, all RCM was underestimated. However, RACMO22T and RCA4 show better adjustment at the simulation of both precipitation and Temperatures despite their significant bias. The bias was deliberately associated with the higher error in simulating maximum and minimum temperature at the highest topography found at sebeta and Addis Ababa catchments. The inter-annual variability of precipitations and temperature was shown as great evidence where the region is under the impact of climate change specifically when the trend of annual projected temperature shown incremental modality. As far as concern the mean climatology analysis by statistical parameters, almost all models perform nearly equal excluding the seasonal point of view in which RCMs performed quite differently during season analysis. In all aspects and evidence by statistically evaluated output realize that RACMO22T and RCA4 were better performed at upper awash catchments although some of their bias and uncertainty were available. Generally, the performance of Regional climate models was different at different catchments along with the specified locations and topographies. Furthermore, the seasonal analysis over Akaki catchment indicates that climate models were more capable of simulating wet season than dry.

Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions

Background: The reproducibility of mitral regurgitation (MR) quantification by cardiovascular magnetic resonance (CMR) imaging using different software solutions remains unclear. This research aimed to investigate the reproducibility of MR quantification between two software solutions: MASS (version 2019 EXP, LUMC, Netherlands) and CAAS (version 5.2, Pie Medical Imaging). Methods: CMR data of 35 patients with MR (12 primary MR, 13 mitral valve repair/replacement, and ten secondary MR) was used. Four methods of MR volume quantification were studied, including two 4D-flow CMR methods (MRMVAV and MRJet) and two non-4D-flow techniques (MRStandard and MRLVRV). We conducted within-software and inter-software correlation and agreement analyses. Results: All methods demonstrated significant correlation between the two software solutions: MRStandard (r=0.92, p<0.001), MRLVRV (r=0.95, p<0.001), MRJet (r=0.86, p<0.001), and MRMVAV (r=0.91, p<0.001). Between CAAS and MASS, MRJet and MRMVAV, compared to each of the four methods, were the only methods not to be associated with significant bias. Conclusions: We conclude that 4D-flow CMR methods demonstrate equivalent reproducibility to non-4D-flow methods but greater levels of agreement between software solutions.

Bayesian Inference of Dwellings Energy Signature at National Scale: Case of the French Residential Stock

Cities take a central place in today’s energy landscape. Urban Buildings Energy Modeling (UBEM) is identified as a promising approach for energy planning and optimization in cities and districts. It generally relies on the use of Building Archetypes, i.e., simplified deterministic models for categorized building typologies. However, this implies large assumptions which may accumulate and induce significant bias on energy consumption estimates. In this work, we address this issue with static stochastic models whose parameters are inferred over national thermo-energy data using Bayesian Inference. We analyze inference results and validate them with a panel of standard indicators. Then, we provide comparative results with deterministic building archetypes and stock data from the TABULA European project. Comparisons between heat loss coefficients show relative coherence between building categories, but highlight some significant bias between both approaches. This bias is also shown in the comparative result of a Monte Carlo simulation using inferred stochastic models for a 10331 dwellings stock. In conclusion, inferred stochastic models show interesting insights over the French dwellings stock and potential for district energy simulation. All code and data involved in this study are released in an open repository.

Non-Contact Video-Based Assessment of the Respiratory Function Using a RGB-D Camera

A fully automatic, non-contact method for the assessment of the respiratory function is proposed using an RGB-D camera-based technology. The proposed algorithm relies on the depth channel of the camera to estimate the movements of the body’s trunk during breathing. It solves in fixed-time complexity, O(1), as the acquisition relies on the mean depth value of the target regions only using the color channels to automatically locate them. This simplicity allows the extraction of real-time values of the respiration, as well as the synchronous assessment on multiple body parts. Two different experiments have been performed: a first one conducted on 10 users in a single region and with a fixed breathing frequency, and a second one conducted on 20 users considering a simultaneous acquisition in two regions. The breath rate has then been computed and compared with a reference measurement. The results show a non-statistically significant bias of 0.11 breaths/min and 96% limits of agreement of −2.21/2.34 breaths/min regarding the breath-by-breath assessment. The overall real-time assessment shows a RMSE of 0.21 breaths/min. We have shown that this method is suitable for applications where respiration needs to be monitored in non-ambulatory and static environments.

Bridge Category Models: Development of Bayesian Modelling Procedures to Account for Bridge Ordinal Ratings for Disease Staging

Disease grading and staging is accomplished through the assignment of an ordinal rating. Bridge ratings occur when a rater assigns two adjacent categories. Most statistical methodology necessitates the use of a single ordinal category. Consequently, bridge ratings often go unreported in clinical research studies. We propose three methodologies (Expanded, Mixture, and Collapsed) Bridge Category Models, to account for bridge ratings. We perform simulations to examine the impact of our approaches on detecting treatment effects, and comment on a real-world scenario of staging liver biopsies. Results indicate that if bridge ratings are not accounted for, disease staging models may exhibit significant bias and precision loss. All models worked well when they corresponded to the data generating mechanism.

New Characteristics and Hedonic Price Index Numbers

Changes in product characteristics on the extensive margin (the addition of new features and the removal of old ones) are an important and hitherto neglected dimension of quality change. Standard techniques for adjusting price indices for new goods cannot handle such changes satisfactorily, and this leads to an economically and statistically significant bias in the measurement of prices and real output. We combine insights from the theories of exact index numbers and demand for characteristics to develop a new method for incorporating changes on the extensive characteristic margin. Applied to U.K. data on new car sales, our method leads to revisions in estimated inflation rates for this commodity group that are both plausible and quantitatively important.