Antibacterial and anti-Trichomonas Vaginalis effects of Rosa Damascena mill petal oil (a persian medicine product), aqueous and hydroalcoholic extracts

Background Oils in traditional medicine are important products and used routinely for therapeutic purposes. Rose oil (Rosa damascene Mill), a product of Persian medicine, is advised for the treatment of Infectious diseases related to the female genitourinary tract. In the present study, R. damascena petal oil, aqueous, and hydroalcoholic extracts were evaluated for their in vitro antibacterial and anti-Trichomonas vaginalis effects. Methods Anti-trichomonas activity evaluation of extracts and oil were assayed by the Homocytometery method. Their antibacterial effects against Escherichia coli, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa, and clinically isolated Group B Streptococcus were assayed by broth microdilution in 96-well plates. Results The MIC of hydroalcoholic and aqueous extracts ranged from 25-50 and 25-100 mg/ml, respectively. Rose oil at all administered doses failed to show any antibacterial activity. Conclusion All extracts and oil concentrations showed some degree of growth inhibition activity on T. vaginalis; however, hydroalcoholic extract was more efficient.

Pharmacognostic, phytochemical and pharmacological aspects of Rosa x damascena Herrm. Georgian cultivar

Rosa x damascena Herrm. represents one of the most popular and important plants of the Rosaceae family. For ages, rose oil, rose water and extracts from its flowers were used in perfumery, cosmetics, aromatherapy, and medicine due to diverse pharmacological efficacy. Nowadays, special attention is paid to the valorization of wastes from the rose oil industry in order to fully recover potent biologically active compounds. The present study describes in detail the microstructural features of the flower petals and provides data on chemical composition and biological potency of the aqueous extract of rose oil waste from the R. damascena Georgian cultivar. Up to 25 constituents were detected by HPLC-MS in the extract, and the content of total flavonoids in the extract reaches 2.29%. Amongst them hyperoside is dominating, which content is not less than 1%. Pharmacological evaluation of the extract on "Hot plate" and carrageenan-induced oedema models in mice revealed analgesic (42%) and anti-inflammatory (67%) effects of the extract. As well, the extract revealed antiplasmodial activity against Plasmodium falciparum (3D7) strain (IC50 =20.31 µg/mL)

Pharmacological assessment of the aqueous extract of rose oil waste from Rosa x damascena Herrm cultivated in Georgia

Among Rosaceae family's most popular and important plants Rosa x damascena Herrm. holds one of the top places due to its centuries-long application in perfumery, cosmetics, aromatherapy and medicine. Despite this, the chemical and pharmacological study of different products obtained from R. damascena still does not lose its relevance. Currently, considerable attention is paid to the valorization of the waste from rose oil production in order to fully utilize valuable physiologically active constituents. The present study provides data on some pharmacological properties of the aqueous extract of rose oil waste from the R. damascena cultivated in Georgia. In particular, evaluation of gastro- and hepatoprotective activity of the aforesaid extract has been carried out in animal models and revealed its efficacy. The extract appeared to dose dependently stimulate leucopoiesis (up to 75%) and prevent ethanol-induced gastric injury (20-80%). As well, the extract ameliorated hepatoxic effects of carbon tetrachloride by 63%.

FORMULATION AND EVALUATION OF POLY HERBAL ANTI AGING FACE CREAMS

Herbal cosmetics are defined as beauty products which possess desirable physiological movement like recuperating, smoothing appearance, improving and molding properties due to the natural fixing.. Herbal Cream is a polyherbal plan that comprises of the concentrates of Aloe barbadensis, Ocimum sanctum, Azadirachta indica and Curcuma longa, Cedro oil, Myristica fragrans, Olium rosae (Rose Oil), Orange Oil, Daucus carota, Prunus dulcis and Ocimum sanctum.. Herbs such as aloe vera leaf, turmeric, banana, neem, papaya, cucumber and other plants are used as herbs in cosmetics. In the current exploration article, the polyherbal face cream is ready by utilizing following fixing that is concentrate of Curcuma longa, Solanum lycoperisum, Carica papaya, Daucus carota, rose oil, olive oil, almond oil, refined water. Solanum lycoperisum is utilized as an enemy of oxidant and forestalls the skin maturing.Olive oil moistures the skin, papaya nourishes the skin and curcumin acts as an antimicrobial agent. The skin maturing is essentially brought about by annihilation of collagen layer in skin which can be forestalled by utilizing almond oil. The pre-arranged polyherbal cream was assessed for the pH, spreadability, homogeneity, thickness, extrudability, invitro dissemination examines, color test, expulsion test, skin bothering and antimicrobial investigations. Among every one of the pre-arranged creams F2 and F3 is discovered to be best details as contrast with another. The total percent drug discharge from the pre-arranged polyherbal cream is discovered to be the 93%.