The Biophysical Modeling of the Hemodynamic in the Human Organism

The circulatory apparatus has as a main function the constant maintaining of the internal environment in all the regions of the organism. The blood is a liquid tissue, being formed of a fundamental substance – plasma and blood cells. Heart is the central organ of the cardiovascular apparatus. The heart muscles have numerous biophysical properties. The cardiac muscle is never tired unless it suffered a pathological process. During the diastole, blood is aspired in the heart and during the systole it is pushed in the big and small circulation. The blood amount pushed from the heart in the vascular system in a certain time represents the blood flow. The biophysical methods are next: we administer a certain substance amount, then its passing speed will depend on its concentration; to apply the calorimetric principles for the measurement of the gastric blood flow; the diagnostic of a chronic peripheral arteriopathy we use the calorimetric method is based on measuring the heat being introduced in a certain amount of water which has known temperature; one of the most often used methods for the evaluation of the use of radioisotopes in the cardio-vascular system is the compartment method. Any attempt to apply biophysics to the life systems involves three stages. First we observe the phenomena and formulate a biophysical description in the form of equations; after to solve the equations. Finally we return to the real life system and interpret this solution in terms of reality, this interpretation may requiew experimental testing.

Some Biophysical Modeling of the Human Circulation Apparatus

Statistics from Hungary over the last seven years clearly show that diseases of the circulatory device lead the statistics on the causes of death. The Hungarian trend is the same as the global trend, with circulatory system disease being the most common cause of death in every country. The modeling of the blood volume, if we administer a certain substance amount, then its passing speed will depend on its concentration, hence the volume at which it spreads in the deposit. Consider the contraction and relaxation of the atrium/ventricle of the human heart; use the function of the rhythmic change for this. We apply the calorimetric principles for the measurement of the gastric blood flow. In the physio­pathology research of the circulation in arteriopathic people, when there are necessary arguments refering to the efficiency of new medicines or for the purpose of reestablishing the work capacity, the clinic diagnostic must be completed with laboratory samples: regional debt, peripheral arterial resistance, circulation time. Its measuring can be made with a normal double walls calorimeter and we measure the water temperature variations. Knowing the values of the previous formulas and the mass of blood circulated in that segment, we find out the segment’s flow. The human organism is a system because it is made up of a finite number of interacting p1, p2,… pn elements, characterized by the quantitative degree of q1, q2,… qn. The circulatory apparatus is a subsystem of the human body. In our opinion, the circulatory device should have a control associated with its own structure, which is likely to consist of neurons with hyperordonated spatial structure, called the “hypothetical secondary brain”, which performs certain control functions. This “hypothetical secondary brain” of the circulatory apparatus, in humans, functions continuously throughout their life.

Stroke as a an initial presentation of SARS-COV2 infection: a brief report

The novel Coronavirus 19 infection spread rapidly from Wuhan, Hubei Province – China, to the worldwide, becoming a pandemic. The infection does not cause only flu-like syndrome (fever, dry cough and shortness of breath) and respiratory distress of varying severity but also affects the kidneys, the heart, the nervous system and the circulatory apparatus, causing thromboembolic events. Usually these problems occur in patients with severe respiratory failure admitted to Intensive Care Unit and with pre-existing comorbidities.We report the case of a patient without Covid symptoms who had thrombotic stroke as the presenting features of Coronavirus infection.

Circulatory Disturbance of the First Metatarsal Head after Chevron Osteotomy as Shown by Bone Scintigraphy

Distal osteotomies, such as Chevron osteotomies, have a potentially high risk for circulatory disturbance, since they transect part of the circulatory apparatus. An increased risk of up to 40% of avascular necrosis diagnosed radiographically has been reported when the osteotomy is combined with adductor tenotomy. On the other hand, new circulatory studies indicate that the circulation does not go in direct proximity to the adductor tendon. In this prospective study, 38 consecutive patients (41 feet) were randomized to Chevron osteotomy alone or Chevron osteotomy with adductor tenotomy. They were investigated 2 to 9 days postoperatively with 99mTc-methylene diphosphonate scintigraphy as well as x-rays and clinical examination. The average follow up was 19 months (range 12–48 months). Three defects were found in those operated with Chevron osteotomy alone, and one defect was found in a patient operated with Chevron osteotomy and adductor tenotomy. None of the patients had symptoms attributable to reduced circulation of the metatarsal head. Repeat scans showed healing in all four cases. Radiographs failed to show any signs of necrosis. Thus, Chevron osteotomy is a safe method in the treatment of hallux valgus which can be combined with adductor tenotomy without increasing the risk for circulatory disturbance.

THE Hg 6(3P1) PHOTOSENSITIZATION OF CHLORODIFLUOROMETHANE

The reaction was studied in a circulatory apparatus under a variety of conditions. The sole primary process occurring is C—Cl bond scission. The Cl atoms formed in the primary step, through an abstractive attack on the substrate, generate chlorodifluoromethyl radicals (CF2Cl) All principal reaction products, CF2H2, CF2Cl2, CF2ClCF2Cl, CF2HCF2H, and CF2HCF2Cl, can be accounted for by the combination–disproportionation reactions of the CF2H• and CF2Cl• radicals. The observed strong dependence of the primary quantum yields on the incident light intensities has been ascribed to a rapid substrate-reforming step.