Denture Stomatitis Revisited: A Summary of Systematic Reviews in the Past Decade and Two Case Reports of Papillary Hyperplasia of Unusual Locations

Objectives. Denture stomatitis is a mucosal condition associated with complete and partial removable dentures. This paper presents a short review of the literature on this topic with more emphasis on the treatment protocols of denture stomatitis as studied in recent systematic reviews. Methods. A general review of the literature was carried out in the first part of this paper, and then the most recent systematic reviews on the treatment protocols of denture stomatitis were summarized. Results. Fifteen systematic reviews were collected and classified into six main treatment protocols. Conclusions. Dentist knowledge of up-to-date treatment options of denture stomatitis will assist comprehensive treatment planning. However, the newer methods of denture disinfection need further studies before recommendation.

Partial uterine prolapse and ovarian cysts in two Djungarian hamsters

A 2-year-old multiparous (Case 1) and a 2.5-year-old nulliparous (Case 2) Djungarian hamster each presented with a history of a prolapsed mass from the vulva. A partial uterine prolapse was diagnosed in both cases, according to the clinical and diagnostic examinations. The prolapsed mass was replaced in each hamster, and an ovariohysterectomy was performed. The histopathological examination of the removed tissues revealed a cyst and papillary hyperplasia in the ovary. This first case report, to our knowledge, demonstrates the possibility of a uterine prolapse with a cyst and papillary hyperplasia in the ovary and how to surgically manage this condition. The report could also contribute to having a better understanding of the occurrence of a uterine prolapse without parturition in hamsters.

Etiology and Management of Inflammatory Papillary Hyperplasia in Completely Edentulous Patients - A Review

Oral mucosa of complete denture wearing patients is subjected to varying amount of stresses as compared to patient having natural teeth. This can leads to different type of oral mucosal lesions like denture stomatitis, epulis fissuratum, angular cheilitis, traumatic ulcers, inflammatory papillary hyperplasia (IPH) etc. IPH is a type of chronic inflammatory proliferative lesion characterized by numerous small, wart like edematous red papillary growth most commonly seen in deepest part of the palate. Review of literature suggest denture associated widely distributed etiology for IPH like over accentuation of palatal relief and vacuum chamber in upper denture, old ill fitting dentures, poor denture hygiene, continuous denture wearing habit, faulty occlusion, skidding of instable denture etc. Treatment for IPH varies with the severity of the condition and may range from conservative to surgical depending on clinical presentation. Conservative approach include discontinuing use of ill fitting denture, correction of faulty prostheses, improving the oral and denture hygiene and antifungal drugs. However, the surgical approach is used when the lesion is more aggressive and this include supraperiosteal excision, resesctive surgery, cryotherapy, and electrosurgery, blade-loop surgery, fulguration, and mucoabrasion or laser surgery. As a method of prevention patient should be advised to avoid continuous day and night wearing of denture. Additionally, avoid providing excessive relief in the palatal region, as these areas become site for bacterial and fungal colonization. Patients should be well motivated for proper care and maintenance of denture hygiene and also for the importance of periodic dental visits and follow-ups.

A case of a vaginal Brenner tumor without a gland mimicking a borderline tumor: unusual morphology and diagnostic pitfalls

Brenner tumor is a rare neoplasm of the vagina. This tumor is diagnosed according to the criteria of ovarian tumors. We report here a 64-year-old postmenopausal woman with a 2.0-cm sessile vaginal polyp for 9 years. Microscopic examination showed unusual features of no gland appearing in the tumor, but the other two characteristic components of transitional islands and dense fibrous stroma were observed. The tumor was diagnosed as a vaginal Brenner tumor on the basis of the definition proposed by the World Health Organization classification of female reproductive organ tumors. In our case, part of the epithelial nests of the Brenner tumor showed basaloid cell differentiation with peripheral palisading, and irregular papillary hyperplasia was observed around the epithelial nests similar to a borderline tumor. However, no mitotic activity or nuclear atypia was present in either the epithelial or stromal components. The presence of epithelial nests requires attention in the medical history of the patient. Our patient did not have a history of primary urothelial carcinoma. Our patient’s benign vaginal Brenner tumor with different morphological characteristics supports the current notion that Walthard nests might act as possible precursor lesions.

The Role of Helicobacter Pylori in Development of Lesion in Oral Cavity

SummaryBackground/Aim: to examine the connection of H. Pylori in saliva and biopsy material with oral lesions.Material and Methods: Sixty patients with dyspeptic complaints were followed up at the Clinic for Gastroenterology at University Medical Clinical Centre in Skopje, divided into two groups: first group consisted of 30 patients without presence of H. pylori, and the second group with 30 subjects and presence of H. pylori. The presence or absence of H. pylori has been ascertained after endoscopic examination-gastroscopy, and implemented urease test (CLO-test). All patients were clinically followed in order to determinate mouth burning, recurrent aphthous stomatitis (RAS), acid taste and lingual papillary hyperplasia according to Cohen and Proctor. The presence of H. pylori in saliva has been ascertained before endoscopic examination, after chewing Orbit gum without sugar for 1 min using by Pronto dry test. Determination of H. pylori in biopsy material has been ascertained by rapid urease test (RUT).Results: At 30 patients with dyspeptic complaints and presence of Helicobacter pylori, 16 patients (53,33%) had lingual papillary hyperplasia, acid taste, burning mouth and recurrent aphthous stomatitis (RAS). At 4 patients (13,33%) was confirmed acid taste, and also at 4 patients (13,33%) burning mouth. At 2 patients (6,67%) was confirmed lingual papillary hyperplasia, burning mouth, and recurrent aphthous stomatitis (RAS). At the same time, at 2 patients (6,67%) was confirmed burning mouth, and recurrent aphthous stomatitis (RAS), until at 1 patient (3,33%) lingual papillary hyperplasia, as at 1 patient (3,33%) lingual papillary hyperplasia and acid taste. At patients without presence of Helicobacter pylori but with dyspeptic complaints, was confirmed burning mouth in 14 patients (46,67%), lingual papillary hyperplasia, burning mouth, and acid taste in 7 patients (23,33%); in 3 patients (10,00) lingual papillary hyperplasia, burning mouth, and in 2 patients (6,67%) was confirmed recurrent aphthous stomatitis (RAS). Acid taste was registered in 2 patients (6,67%), and also lingual papillary hyperplasia in 2 patients (6,67%). There was a significant differences in clinical aspect between the patients with and without presence of H. pylori, for p< 0,01(p= 0,002); Pearson Chi-square= 20,10 и and p<0,05(p= 0,01).Conclusions: H. pylori in saliva and biopsy material detected with CLO test are reason for oral lesions at patients with dyspeptic complaints who have the presence of H. pylori.

Surgical and nonsurgical treatment of papillary hyperplasia: A case report

Dentures with dental plaque predispose recurrent hyperplasia on the palatal mucosa. Surgical procedures for the treatment of inflammatory papillary hyperplasia involve postsurgical discomfort and morbidity. This repot describes clinical and histologic aspects of a patient with severe akantolitic inflammatory papillary hyperplasia. The palatal mucosa was treated with a surgical bur with a low-speed handpiece. A new removable denture was performed and adapted. A follow-up of 4 years showed staility of health at palatal mucosa. Patient referred low discomfort and morbidity when using bur technique. Control of removable denture was critical for long-term healing and soft tissue stability.